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Nature Biotechnology
ISSUE
May 2002, Volume 20 No 5
In This Issue
Editorial
Business and Regulatory NewsAnalysis | In Brief
OpinionCommentary | Fool's Corner | Correspondence
Features
Research NewsNews and Views | In Brief
ResearchArticles | Technical Reports
ResourcesPatents | People | New on the Market
NaturejobsCareers and Recruitment
About the cover
In This Issue Top
PDF
Editorial Top
Turning back the clock p411
doi:10.1038/nbt0502-411
Full text | PDF (34K)
Business and Regulatory News Top
Analysis
Investors remain wary after first quarter downturn pp413 - 414
Liz Fletcher
doi:10.1038/nbt0502-413
Full text | PDF (41K)
NIH outlines goals to counter bioterror p414
Brian B. Reid
doi:10.1038/nbt0502-414
Full text | PDF (29K)
India approves GM cotton p415
K.S. Jayaraman
doi:10.1038/nbt0502-415
Full text | PDF (28K)
Mexico to relax rDNA ban? pp416 - 417
John Hodgson
doi:10.1038/nbt0502-416
Full text | PDF (272K)
Rice data release signals industry willingness to share data pp417 - 418
Jeffrey L. Fox
doi:10.1038/nbt0502-417
Full text | PDF (148K)
Industry opposes genomic legislation p419
Ken Chahine
doi:10.1038/nbt0502-419
Full text | PDF (27K)
In Brief
In Brief pp421 - 423
doi:10.1038/nbt0502-421
Full text | PDF (610K)
Opinion Top
Commentary
Rethinking somatic stem cell plasticity p425
Ihor Lemischka
doi:10.1038/nbt0502-425
Full text | PDF (28K)
A more astonishing hypothesis pp426 - 427
Ron McKay
doi:10.1038/nbt0502-426
Full text | PDF (32K)
Fool's Corner
Elan's attack of Enronitis p429
Tom Jacobs
doi:10.1038/nbt0502-429
Full text | PDF (30K)
Correspondence
Protecting careers, not lives p431
Henry Miller
doi:10.1038/nbt0502-431a
Full text | PDF (275K)
Searching for alternatives pp431 - 432
Ray Greek & Jean Greek
doi:10.1038/nbt0502-431b
Full text | PDF (287K)
Cloning similarities p432
Enrico Baldini
doi:10.1038/nbt0502-432
Full text | PDF (29K)
Features Top
Biotechnology in the Medicon Valley pp433 - 435
Lone Frank
doi:10.1038/nbt0502-433
Abstract | Full text | PDF (536K)
Finnish biotechnology—built on solid foundations pp437 - 440
Riku Lähteenmäki
doi:10.1038/nbt0502-437
Abstract | Full text | PDF (219K)
Time for consolidation in Germany pp441 - 444
Christian Müller & Armin Rump
doi:10.1038/nbt0502-441
Abstract | Full text | PDF (187K)
Research News Top
News and Views
Nuclear reprogramming—alchemy or analysis? pp445 - 446
Patrick S. Western & M. Azim Surani
doi:10.1038/nbt0502-445
Abstract | Full text | PDF (128K)
See also: Research by Håkelien et al.
Expanding small RNA interference pp446 - 448
Thomas Tuschl
doi:10.1038/nbt0502-446
Abstract | Full text | PDF (55K)
See also: Research by Miyagishi & Taira | Research by Lee et al.  | Research by Paul et al.
Bringing picomolar protein detection into proximity pp448 - 449
Michael Famulok
doi:10.1038/nbt0502-448
Abstract | Full text | PDF (44K)
See also: Research by Fredriksson et al.
A new blueprint for plant pathogen resistance pp450 - 451
Heribert Hirt
doi:10.1038/nbt0502-450
Abstract | Full text | PDF (42K)
In Brief
In Brief p453
doi:10.1038/nbt0502-453
Full text | PDF (217K)
Research Top
Articles
Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation pp455 - 459
Kevin Eggan, Anja Rode, Isabell Jentsch, Caroline Samuel, Thomas Hennek, Hartmut Tintrup, Branko Zevnik, Jennifer Erwin, Janet Loring, Laurie Jackson-Grusby, Michael R. Speicher, Ralf Kuehn & Rudolf Jaenisch
doi:10.1038/nbt0502-455
Abstract | Full text | PDF (819K)  | Supplementary Information
Reprogramming fibroblasts to express T-cell functions using cell extracts pp460 - 466
Anne-Mari Håkelien, Helga B. Landsverk, James M. Robl, Bjørn S. Skålhegg & Philippe Collas
doi:10.1038/nbt0502-460
Abstract | Full text | PDF (962K)
See also: Research News by Western & Surani
Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo pp467 - 472
Thi My Anh Neildez-Nguyen, Henri Wajcman, Michael C. Marden, Morad Bensidhoum, Vincent Moncollin, Marie-Catherine Giarratana, Ladan Kobari, Dominique Thierry & Luc Douay
doi:10.1038/nbt0502-467
Abstract | Full text | PDF (1,438K)
Protein detection using proximity-dependent DNA ligation assays pp473 - 477
Simon Fredriksson, Mats Gullberg, Jonas Jarvius, Charlotta Olsson, Kristian Pietras, Sigrún Margrét Gústafsdóttir, Arne Östman & Ulf Landegren
doi:10.1038/nbt0502-473
Abstract | Full text | PDF (1,496K)
See also: Research News by Famulok
An array of target-specific screening strains for antibacterial discovery pp478 - 483
Joseph A. DeVito, Jonathan A. Mills, Veronica G. Liu, Anjana Agarwal, Christine F. Sizemore, Zhongjie Yao, Daniel M. Stoughton, Maria Grazia Cappiello, Maria D.F.S. Barbosa, Lorie A. Foster & David L. Pompliano
doi:10.1038/nbt0502-478
Abstract | Full text | PDF (664K)
Large scale production of recombinant human lactoferrin in the milk of transgenic cows pp484 - 487
Patrick H.C. van Berkel, Mick M. Welling, Marlieke Geerts, Harry A. van Veen, Bep Ravensbergen, Mourad Salaheddine, Ernest K. J. Pauwels, Frank Pieper, Jan H. Nuijens & Peter H. Nibbering
doi:10.1038/nbt0502-484
Abstract | Full text | PDF (310K)
An HGF−MSP chimera disassociates the trophic properties of scatter factors from their pro-invasive activity pp488 - 495
Paolo Michieli, Silvia Cavassa, Cristina Basilico, Annarita De Luca, Massimiliano Mazzone, Cinzia Asti, Riccardo Chiusaroli, Mario Guglielmi, Paola Bossù, Francesco Colotta, Gianfranco Caselli & Paolo M. Comoglio
doi:10.1038/nbt0502-488
Abstract | Full text | PDF (927K)
Technical Reports
U6 promoter−driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells pp497 - 500
Makoto Miyagishi & Kazunari Taira
doi:10.1038/nbt0502-497
Abstract | Full text | PDF (779K)
See also: Research News by Tuschl
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells pp500 - 505
Nan Sook Lee, Taikoh Dohjima, Gerhard Bauer, Haitang Li, Ming-Jie Li, Ali Ehsani, Paul Salvaterra & John Rossi
doi:10.1038/nbt0502-500
Abstract | Full text | PDF (2,587K)
See also: Research News by Tuschl
Effective expression of small interfering RNA in human cells pp505 - 508
Cynthia P. Paul, Paul D. Good, Ira Winer & David R. Engelke
doi:10.1038/nbt0502-505
Abstract | Full text | PDF (1,751K)
See also: Research News by Tuschl
Using the transcriptome to annotate the genome pp508 - 512
Saurabh Saha, Andrew B. Sparks, Carlo Rago, Viatcheslav Akmaev, Clarence J. Wang, Bert Vogelstein, Kenneth W. Kinzler & Victor E. Velculescu
doi:10.1038/nbt0502-508
Abstract | Full text | PDF (793K)  | Supplementary Information
Quantitative proteome analysis by solid-phase isotope tagging and mass spectrometry pp512 - 515
Huilin Zhou, Jeffrey A. Ranish, Julian D. Watts & Ruedi Aebersold
doi:10.1038/nbt0502-512
Abstract | Full text | PDF (64K)  | Supplementary Information
Resources Top
Patents
Patenting bioinformatic inventions: Emerging trends in Europe pp517 - 518
Steven J. Hultquist, Robert Harrison & Yongzhi Yang
doi:10.1038/nbt0502-517
Abstract | Full text | PDF (38K)
Recent patents in tissue engineering p519
doi:10.1038/nbt0502-519
Full text | PDF (22K)
People
People p521
doi:10.1038/nbt0502-521
Full text | PDF (60K)
New on the Market
Mass spectrometry and gene therapy p523
doi:10.1038/nbt0502-523
Full text | PDF (1,165K)
Naturejobs Top
Careers and Recruitment
To recruit the best R&D professionals, understand what drives them pp525 - 526
Charlene Reed
doi:10.1038/nbt0502-525
Abstract | Full text | PDF (31K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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