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| In This Issue | Top |
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| Editorial | Top |
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Turning back the clock p411 doi:10.1038/nbt0502-411 Full text | PDF
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| Business and Regulatory News | Top |
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| Analysis |
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Investors remain wary after first quarter downturn pp413 - 414 Liz Fletcher doi:10.1038/nbt0502-413 Full text | PDF
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NIH outlines goals to counter bioterror p414 Brian B. Reid doi:10.1038/nbt0502-414 Full text | PDF
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India approves GM cotton p415 K.S. Jayaraman doi:10.1038/nbt0502-415 Full text | PDF
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Mexico to relax rDNA ban? pp416 - 417 John Hodgson doi:10.1038/nbt0502-416 Full text | PDF
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Rice data release signals industry willingness to share data pp417 - 418 Jeffrey L. Fox doi:10.1038/nbt0502-417 Full text | PDF
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Industry opposes genomic legislation p419 Ken Chahine doi:10.1038/nbt0502-419 Full text | PDF
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| In Brief |
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In Brief pp421 - 423 doi:10.1038/nbt0502-421 Full text | PDF
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| Opinion | Top |
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| Commentary |
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Rethinking somatic stem cell plasticity p425 Ihor Lemischka doi:10.1038/nbt0502-425 Full text | PDF
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A more astonishing hypothesis pp426 - 427 Ron McKay doi:10.1038/nbt0502-426 Full text | PDF
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| Fool's Corner |
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Elan's attack of Enronitis p429 Tom Jacobs doi:10.1038/nbt0502-429 Full text | PDF
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| Correspondence |
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Protecting careers, not lives p431 Henry Miller doi:10.1038/nbt0502-431a Full text | PDF
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Searching for alternatives pp431 - 432 Ray Greek
& Jean Greek doi:10.1038/nbt0502-431b Full text | PDF
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Cloning similarities p432 Enrico Baldini doi:10.1038/nbt0502-432 Full text | PDF
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| Features | Top |
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Biotechnology in the Medicon Valley pp433 - 435 Lone Frank doi:10.1038/nbt0502-433 Abstract | Full text | PDF
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Finnish biotechnologybuilt on solid foundations pp437 - 440 Riku Lähteenmäki doi:10.1038/nbt0502-437 Abstract | Full text | PDF
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Time for consolidation in Germany pp441 - 444 Christian Müller
& Armin Rump doi:10.1038/nbt0502-441 Abstract | Full text | PDF
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| Research News | Top |
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| News and Views |
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Nuclear reprogrammingalchemy or analysis? pp445 - 446 Patrick S. Western
& M. Azim Surani doi:10.1038/nbt0502-445 Abstract | Full text | PDF
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See also: Research by Håkelien et al. |
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Expanding small RNA interference pp446 - 448 Thomas Tuschl doi:10.1038/nbt0502-446 Abstract | Full text | PDF
(55K)
See also: Research by Miyagishi & Taira | Research by Lee et al. | Research by Paul et al. |
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Bringing picomolar protein detection into proximity pp448 - 449 Michael Famulok doi:10.1038/nbt0502-448 Abstract | Full text | PDF
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A new blueprint for plant pathogen resistance pp450 - 451 Heribert Hirt doi:10.1038/nbt0502-450 Abstract | Full text | PDF
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| In Brief |
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In Brief p453 doi:10.1038/nbt0502-453 Full text | PDF
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| Research | Top |
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| Articles |
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Male and female mice derived from the same embryonic stem cell clone by tetraploid embryo complementation pp455 - 459 Kevin Eggan, Anja Rode, Isabell Jentsch, Caroline Samuel, Thomas Hennek, Hartmut Tintrup, Branko Zevnik, Jennifer Erwin, Janet Loring, Laurie Jackson-Grusby, Michael R. Speicher, Ralf Kuehn
& Rudolf Jaenisch doi:10.1038/nbt0502-455 Abstract | Full text | PDF
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Reprogramming fibroblasts to express T-cell functions using cell
extracts pp460 - 466 Anne-Mari Håkelien, Helga B. Landsverk, James M. Robl, Bjørn S. Skålhegg
& Philippe Collas doi:10.1038/nbt0502-460 Abstract | Full text | PDF
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See also: Research News by Western & Surani |
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Human erythroid cells produced ex vivo at large scale
differentiate into red blood cells in vivo pp467 - 472 Thi My Anh Neildez-Nguyen, Henri Wajcman, Michael C. Marden, Morad Bensidhoum, Vincent Moncollin, Marie-Catherine Giarratana, Ladan Kobari, Dominique Thierry
& Luc Douay doi:10.1038/nbt0502-467 Abstract | Full text | PDF
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Protein detection using proximity-dependent DNA ligation assays pp473 - 477 Simon Fredriksson, Mats Gullberg, Jonas Jarvius, Charlotta Olsson, Kristian Pietras, Sigrún
Margrét Gústafsdóttir, Arne Östman
& Ulf Landegren doi:10.1038/nbt0502-473 Abstract | Full text | PDF
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See also: Research News by Famulok |
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An array of target-specific screening strains for antibacterial discovery pp478 - 483 Joseph A. DeVito, Jonathan A. Mills, Veronica G. Liu, Anjana Agarwal, Christine F. Sizemore, Zhongjie Yao, Daniel M. Stoughton, Maria Grazia Cappiello, Maria D.F.S. Barbosa, Lorie A. Foster
& David L. Pompliano doi:10.1038/nbt0502-478 Abstract | Full text | PDF
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Large scale production of recombinant human lactoferrin in the milk of transgenic cows pp484 - 487 Patrick H.C. van Berkel, Mick M. Welling, Marlieke Geerts, Harry A. van Veen, Bep Ravensbergen, Mourad Salaheddine, Ernest K. J. Pauwels, Frank Pieper, Jan H. Nuijens
& Peter H. Nibbering doi:10.1038/nbt0502-484 Abstract | Full text | PDF
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An HGF−MSP chimera disassociates the trophic properties of scatter factors from their pro-invasive activity pp488 - 495 Paolo Michieli, Silvia Cavassa, Cristina Basilico, Annarita De Luca, Massimiliano Mazzone, Cinzia Asti, Riccardo Chiusaroli, Mario Guglielmi, Paola Bossù, Francesco Colotta, Gianfranco Caselli
& Paolo M. Comoglio doi:10.1038/nbt0502-488 Abstract | Full text | PDF
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| Technical Reports |
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U6 promoter−driven siRNAs with four uridine 3' overhangs
efficiently suppress targeted gene expression in mammalian cells pp497 - 500 Makoto Miyagishi
& Kazunari Taira doi:10.1038/nbt0502-497 Abstract | Full text | PDF
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See also: Research News by Tuschl |
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Expression of small interfering RNAs targeted against HIV-1 rev
transcripts in human cells pp500 - 505 Nan Sook Lee, Taikoh Dohjima, Gerhard Bauer, Haitang Li, Ming-Jie Li, Ali Ehsani, Paul Salvaterra
& John Rossi doi:10.1038/nbt0502-500 Abstract | Full text | PDF
(2,587K)
See also: Research News by Tuschl |
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Effective expression of small interfering RNA in human cells pp505 - 508 Cynthia P. Paul, Paul D. Good, Ira Winer
& David R. Engelke doi:10.1038/nbt0502-505 Abstract | Full text | PDF
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See also: Research News by Tuschl |
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Using the transcriptome to annotate the genome pp508 - 512 Saurabh Saha, Andrew B. Sparks, Carlo Rago, Viatcheslav Akmaev, Clarence J. Wang, Bert Vogelstein, Kenneth W. Kinzler
& Victor E. Velculescu doi:10.1038/nbt0502-508 Abstract | Full text | PDF
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| Supplementary Information |
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Quantitative proteome analysis by solid-phase isotope tagging and mass
spectrometry pp512 - 515 Huilin Zhou, Jeffrey A. Ranish, Julian D. Watts
& Ruedi Aebersold doi:10.1038/nbt0502-512 Abstract | Full text | PDF
(64K)
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| Resources | Top |
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| Patents |
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Patenting bioinformatic inventions: Emerging trends in Europe pp517 - 518 Steven J. Hultquist, Robert Harrison
& Yongzhi Yang doi:10.1038/nbt0502-517 Abstract | Full text | PDF
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Recent patents in tissue engineering p519 doi:10.1038/nbt0502-519 Full text | PDF
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| People |
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People p521 doi:10.1038/nbt0502-521 Full text | PDF
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| New on the Market |
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Mass spectrometry and gene therapy p523 doi:10.1038/nbt0502-523 Full text | PDF
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| Naturejobs | Top |
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| Careers and Recruitment |
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To recruit the best R&D professionals, understand what drives them pp525 - 526 Charlene Reed doi:10.1038/nbt0502-525 Abstract | Full text | PDF
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