Nature Biotechnology
20, 448 - 449 (2002)
doi:10.1038/nbt0502-448
Bringing picomolar protein detection into proximityMichael Famulok
Michael Famulok is a professor at the
Kekulé Institute of Organic Chemistry and Biochemistry,
Universität Bonn, Gerhard-Domagk-Strasse 1,
53121 Bonn, Germany
m.famulok@uni-bonn.de
Combining target recognition by two aptamers, enzymatic ligation,
and PCR, the proximity ligation method enables the detection of minute amounts
of proteins.
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