Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Spiderless spider webs

A silk protein has now been heterologously expressed, isolated, and spun into fibers in vitro for the first time.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Webs without spiders.

References

  1. Lazaris, A. et al. Science 295, 472–476 (2002).

    Article  CAS  Google Scholar 

  2. Hayashi, C.Y. & Lewis, R.V. Science 287, 1477–1479 (2000).

    Article  CAS  Google Scholar 

  3. Guerette, P.A. et al. Science 272, 112–114 (1996).

    Article  CAS  Google Scholar 

  4. Hinman, M.B., Jones, J.A., & Lewis, R.V. Trends Biotechnol. 18, 374 (2000).

    Article  CAS  Google Scholar 

  5. Prince, J.T. et al. Biochemistry 34, 10879–10884 (1995).

    Article  CAS  Google Scholar 

  6. Winkler S. et al. Biochemistry 39, 12739–12746 (2000).

    Article  CAS  Google Scholar 

  7. Viney, C. et al. in Silk polymers: Materials science and biotechnology, vol. 544. (Eds, Kaplan, D.L., Adams, W., Farmer, B., Viney, C.). (American Chemical Society, Washington, DC, 1994) 120–136.

    Google Scholar 

  8. Vollrath, F. & Knight, D.P. Nature 410, 541 (2001).

    Article  CAS  Google Scholar 

  9. Wilson, D., Valluzzi, R., & Kaplan, D.L. Biophys. J. 78, 2690–2701 (2000).

    Article  CAS  Google Scholar 

  10. Zhou, C.-Z. et al. Nucleic Acids Res. 28, 2413–2419 (2000).

    Article  CAS  Google Scholar 

  11. Sezutsu, H. & Yukuhiro, K. J. Mol. Evol. 51, 329–338 (2000).

    Article  CAS  Google Scholar 

  12. Sofia, S. et al. J. Biomed. Materials Res. 54, 139–148 (2001).

    Article  CAS  Google Scholar 

  13. Minoura, N. et al. Biochem. Biophys. Res. Commun. 208, 511–516 (1995).

    Article  CAS  Google Scholar 

  14. Scheller, J., Guhrs, K.-H., Grosse, F., & Conrad, U. Nat. Biotechnol. 19, 573–577 (2001)

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kaplan, D. Spiderless spider webs. Nat Biotechnol 20, 239–240 (2002). https://doi.org/10.1038/nbt0302-239

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt0302-239

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing