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Journal home Advance online publication Current issue Archive Press releases Supplements Focuses Conferences Guide to authors Online submission Permissions For referees Free online issue Contact the journal Subscribe Advertising work@npg naturereprints About this site For librarians   NPG Resources Bioentrepreneur Nature Reviews Drug Discovery Nature Nature Medicine Nature Genetics Nature Reviews Genetics Nature Methods Nature Chemical Biology news@nature.com Clinical Pharmacology & Therapeutics Nature Conferences NPG Subject areas Biotechnology Cancer Chemistry Clinical Medicine Dentistry Development Drug Discovery Earth Sciences Evolution & Ecology Genetics Immunology Materials Science Medical Research Microbiology Molecular Cell Biology Neuroscience Pharmacology Physics Browse all publications News and Views Nature Biotechnology  20, 1210 - 1212 (2002) doi:10.1038/nbt1202-1210 It takes three to tango Olga Lomovskaya1, Helen I. Zgurskaya2 & Hiroshi Nikaido3 1  Olga Lomovskaya is associate director of Efflux Biology at Essential Therapeutics, Inc., Mountain View, CA 94043 2  Helen I. Zgurskaya is assistant professor in the Department of Chemistry & Biochemistry at the University of Oklahoma, Norman, OK 73019-3051 3  Hiroshi Nikaido is professor in the Department of Molecular & Cell Biology at the University of California, Berkeley, Berkeley, CA 94720-3206 olga@etrx.com The recently determined high-resolution crystal structure of the bacterial multidrug resistance transporter AcrB brings us one step closer to the design of more effective therapeutic agents. MORE ARTICLES LIKE THIS These links to content published by NPG are automatically generated REVIEWS Microbial genetics: Exploiting genomics, genetics and chemistry to combat antibiotic resistance Nature Reviews Genetics Review (01 Jun 2003) NEWS AND VIEWS TolC, a macromolecular periplasmic 'chunnel' Nature Structural Biology News and Views (01 Jul 2000) RESEARCH Crystal structure of bacterial multidrug efflux transporter AcrB Nature Article (10 Oct 2002) Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export Nature Article (22 Jun 2000)  Top Abstract Previous | Next Table of contents Full text Download PDF Send to a friend Save this link Open Innovation Challenges Novel Approaches to Protecting Maize from Insect Damage Deadline: Nov 29 2009 Reward: $20,000 USD The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re... Methods to Analyze Consumer Emotions Deadline: Jan 17 2010 Reward: $10,000 USD The Seeker is looking for methods to analyze consumer emotions. This Challenge requires only a writ... More Challenges Powered by: nature jobs Head, Medical Writing Cactus Global Mumbai 400053 India Organic Chemistry Praj Matrix - Praj Industries Ltd Pune, Maharashtra Pune-411021 India More science jobs Post a job for free Figures & Tables Export citation Search buyers guide:   ADVERTISEMENT

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