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Volume 20 Issue 1, January 2002

The cover shows the airways of the bronchus of a patient suffering from cystic fibrosis. The airways are lined with hair like cilia (dark blue, purple) which normally clear bacteria and mucus (yellow) from the lungs. In cystic fibrosis, mucus accumulates and life-threatening infections develop. On p. 47, Liu and colleagues use RNA trans-splicing to attempt to correct one of the underlying genetic mutations. Scanning electron micrograph by Jergen Burger, Max Planck Institute, Science Photo Library.

Volume 20 Issue 1

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Business and Regulatory News

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Commentary

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Book Review

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Correspondence

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Feature

  • As bioterrorism becomes a reality, US federal agencies are turning to biotechnology for new means of detection and safer therapeutics. But does the industry have all the answers?

    • Eric Niiler
    Feature
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News & Views

  • Random transposon mutagenesis, microarray analysis, and genome-wide homology searches have been used to identify 137 previously non-annotated genes in yeast.

    • Stephen Oliver
    News & Views

  • Self-assembling organic molecules with a mineral coat may enable new approaches to bone tissue engineering.

    • William L. Murphy
    • David J. Mooney
    News & Views

  • Correcting defective genes at the mRNA level shows promise for the treatment of cystic fibrosis.

    • Ronald G. Crystal
    News & Views
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News in Brief

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Technical Report

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People

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Quiz

  • As the only palindromic year this century stands before you, the editors of Nature Biotechnology have attempted to recall something of the preceding 12 months. While the questions below and answers opposite certainly reflect our particular perspective on biotechnology, we hope they retain something of the spirit of 2001.

    • John Hodgson
    • Liz Fletcher
    • Meeghan Sinclair
    Quiz
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