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| Opinion |  Top |
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| Editorials |
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Who pulls the strings in biotechnology? p1
doi:10.1038/71855
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(92K)
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A Y3K bug p1
doi:10.1038/71857
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(92K)
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Some news about research p1
doi:10.1038/71859
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(92K)
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| Commentary |
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The tragedy of the commoners: biotechnology and its publics pp2 - 4
Ambuj Sagar, Arthur Daemmrich
& Mona Ashiya
doi:10.1038/71861
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(199K)
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| Correspondence |
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Science-based policy p5
Henry I. Miller
doi:10.1038/71932
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(101K)
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Cloning nonuniformity p5
R.J. Wilkins
doi:10.1038/71934
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(101K)
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Quantitative RT-PCR p5
Bertrand Lambolez
& Jean Rossier
doi:10.1038/71936
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(101K)
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| In Brief | Top |
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| Business and Regulatory News |
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Roche's Taq patent invalid p7
Eric Niiler
doi:10.1038/71967
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(112K)
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Cartoon p7
doi:10.1038/71969
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(112K)
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Two patent disputes settled p7
Jeff Fox
doi:10.1038/71972
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(112K)
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Megamergers continue p7
Emma Dorey
doi:10.1038/71974
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(112K)
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GMO roundup p7
John Hodgson
doi:10.1038/71976
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(112K)
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Stan Fields wins award p8
Emma Dorey
doi:10.1038/71994
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(93K)
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Activists sue industry p8
Jeff Fox
doi:10.1038/71997
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(93K)
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Gene therapy inquiry p8
Jeff Fox
doi:10.1038/71999
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(93K)
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Blue Gene to study folding p8
Alan Dove
doi:10.1038/72001
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(93K)
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Research collaborations p8
doi:10.1038/72003
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(93K)
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| Research News |
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Artificial corneas p9
Alan Dove
doi:10.1038/72023
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(100K)
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Genome roundup p9
Andrew Marshall
doi:10.1038/72025
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(100K)
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Illuminating applications for transgenic frogs p9
Alan Dove
doi:10.1038/72027
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(100K)
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Bacteria with a silver lining p9
Robert Frederickson
doi:10.1038/72030
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(100K)
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Getting down to life's essentials p9
Alan Dove
doi:10.1038/72032
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(100K)
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| This Month in Biotechnology |
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Mixed waste bioremediation p10
Natalie DeWitt
doi:10.1038/71790
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(135K)
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Screening for site-specific proteases p10
Natalie DeWitt
doi:10.1038/71793
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(135K)
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Glow worm p10
Natalie DeWitt
doi:10.1038/71795
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(135K)
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Gene therapy gets hairy p10
Natalie DeWitt
doi:10.1038/71798
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(135K)
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A new array of possibilities p10
Robert Frederickson
doi:10.1038/71801
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(135K)
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Macrophage therapies become more selective p10
Robert Frederickson
doi:10.1038/71803
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(135K)
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Longer life in vitro with telomerase p10
Robert Frederickson
doi:10.1038/71806
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(135K)
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Recombining larger phage libraries p11
Natalie DeWitt
doi:10.1038/71823
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(120K)
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A fish story p11
Natalie DeWitt
doi:10.1038/71825
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(120K)
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Peptides binding peptides p11
Robert Frederickson
doi:10.1038/71828
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(120K)
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Alternative antisense p11
Robert Frederickson
doi:10.1038/71830
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(120K)
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Buffering proteins against delivery problems p11
Robert Frederickson
doi:10.1038/71833
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(120K)
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Technical Reports p11
Robert Frederickson
doi:10.1038/71836
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(120K)
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| Analysis | Top |
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| Business and Regulatory News |
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Scientists avert new GMO crisis p13
John Hodgson
doi:10.1038/71838
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(110K)
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Demise of the life science company begins p14
Eric Niiler
doi:10.1038/71841
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(133K)
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FDA not yet moved by biotech food critics p15
Jeffrey L. Fox
doi:10.1038/71844
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(99K)
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Four companies announce discovery of  -secretase gene p16
Bette Phimister
doi:10.1038/71846
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(100K)
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Japan creeps toward proteomics pp16 - 17
Asako Saegusa
doi:10.1038/71848
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(107K)
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Traders predict biodiversity turmoil pp17 - 18
John Hodgson
doi:10.1038/71850
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(103K)
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Isis and antisense face crucial test without Novartis p19
Alan Dove
doi:10.1038/71852
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(100K)
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| News and Views |
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The hair follicle as a gene therapy target pp20 - 21
Robert M. Hoffman
doi:10.1038/71866
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(129K)
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Fishing for mutations pp21 - 22
James G. Burkhart
doi:10.1038/71869
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(120K)
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The use of telomerized cells for tissue engineering pp22 - 23
Jerry W. Shay
& Woodring E. Wright
doi:10.1038/71872
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(105K)
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Protein stability in controlled-release systems pp24 - 25
K. Fu, A.M. Klibanov
& R. Langer
doi:10.1038/71875
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(113K)
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Macrophages and cutaneous inflammation pp25 - 26
Thomas S. McCormick, Seth R. Stevens
& Kefei Kang
doi:10.1038/71879
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(687K)
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Computing protein function p27
Sarah A. Teichmann
& Graeme Mitchison
doi:10.1038/71882
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(92K)
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| Feature | Top |
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Crystal gazing the new biotechnologies pp29 - 31
John Hodgson
doi:10.1038/71884
Abstract | Full text | PDF
(238K)
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| Research | Top |
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| Review |
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Synthetic DNA delivery systems pp33 - 37
Dan Luo
& W. Mark Saltzman
doi:10.1038/71889
Abstract | Full text | PDF
(211K)
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| Articles |
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Formation of functional tissue from transplanted adrenocortical cells
expressing telomerase reverse transcriptase pp39 - 42
Michael Thomas, Lianqing Yang
& Peter J. Hornsby
doi:10.1038/71894
Abstract | Full text | PDF
(313K)
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Localized in vivo genotypic and phenotypic correction of the albino mutation
in skin by RNA-DNA oligonucleotide pp43 - 47
Vitali Alexeev, Olga Igoucheva, Alla Domashenko, George Cotsarelis
& Kyonggeun Yoon
doi:10.1038/71901
Abstract | Full text | PDF
(544K)
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Resolution of cutaneous inflammation after local elimination of macrophages
pp48 - 51
Theo Thepen, A. J. Hanneke van Vuuren, Rebecca C. M. Kiekens, Cora A. Damen, Wim C. Vooijs
& Jan G. J. van de Winkel
doi:10.1038/71908
Abstract | Full text | PDF
(514K)
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Stabilization of proteins encapsulated in injectable poly (lactide-
co-glycolide) pp52 - 57
Gaozhong Zhu, Susan R. Mallery
& Steven P. Schwendeman
doi:10.1038/71916
Abstract | Full text | PDF
(524K)
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Intracellular mRNA cleavage induced through activation of RNase P by
nuclease-resistant external guide sequences pp58 - 61
Michael Ma, Lyuba Benimetskaya, Irina Lebedeva, Jeanne Dignam, Garry Takle
& C.A. Stein
doi:10.1038/71924
Abstract | Full text | PDF
(362K)
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Transgenic zebrafish for detecting mutations caused by compounds in aquatic
environments pp62 - 65
Kimiko Amanuma, Hiroyuki Takeda, Hiroshi Amanuma
& Yasunobu Aoki
doi:10.1038/71938
Abstract | Full text | PDF
(201K)
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Identification of -secretase-like activity using a mass spectrometry-based
assay system pp66 - 70
Fiona Grüninger-Leitch, Peter Berndt, Hanno Langen, Peter Nelboeck
& Heinz Döbeli
doi:10.1038/71944
Abstract | Full text | PDF
(578K)
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Selection and application of peptide-binding peptides pp71 - 74
Zhiwen Zhang, Weiguang Zhu
& Thomas Kodadek
doi:10.1038/71951
Abstract | Full text | PDF
(317K)
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Exploiting recombination in single bacteria to make large phage antibody
libraries pp75 - 80
Daniele Sblattero
& Andrew Bradbury
doi:10.1038/71958
Abstract | Full text | PDF
(511K)
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Germline transformation of the silkworm Bombyx mori L. using a
piggyBac transposon-derived vector pp81 - 84
Toshiki Tamura, Chantal Thibert, Corinne Royer, Toshio Kanda, Abraham Eappen, Mari Kamba, Natuo Kômoto, Jean-Luc Thomas, Bernard Mauchamp, Gérard Chavancy, Paul Shirk, Malcolm Fraser, Jean-Claude Prudhomme
& Pierre Couble
doi:10.1038/71978
Abstract | Full text | PDF
(483K)
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Engineering Deinococcus radiodurans for metal remediation in radioactive
mixed waste environments pp85 - 90
Hassan Brim, Sara C. McFarlan, James K. Fredrickson, Kenneth W. Minton, Min Zhai, Lawrence P. Wackett
& Michael J. Daly
doi:10.1038/71986
Abstract | Full text | PDF
(720K)
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Screening unlabeled DNA targets with randomly ordered fiber-optic gene
arrays pp91 - 94
Frank J. Steemers, Jane A. Ferguson
& David R. Walt
doi:10.1038/72006
Abstract | Full text | PDF
(286K)
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| Technical Reports |
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MALDI-TOF based mutation detection using tagged in vitro synthesized
peptides pp95 - 97
Alex M. Garvin, Kenneth C. Parker
& Larry Haff
doi:10.1038/72013
Abstract | Full text | PDF
(478K)
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Insertional transposon mutagenesis by electroporation of released Tn5
transposition complexes pp97 - 100
Igor Y. Goryshin, Jerry Jendrisak, Les M. Hoffman, Ronald Meis
& William S. Reznikoff
doi:10.1038/72017
Abstract | Full text | PDF
(163K)
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| Resources | Top |
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| Patents |
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The Supreme Court's war on intellectual property pp101 - 102
James N. Gardner
doi:10.1038/71772
Abstract | Full text | PDF
(124K)
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Recent patents in arthritis research p103
doi:10.1038/71775
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(68K)
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| In the Laboratory |
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Microscale sample preparation pp104 - 105
Malcolm G. Pluskal
doi:10.1038/71778
Abstract | Full text | PDF
(330K)
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| Careers and Recruitment |
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Lemons into lemonade p106
Daniel Coulter
doi:10.1038/71783
Abstract | Full text | PDF
(86K)
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| People |
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People p107
doi:10.1038/71785
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(85K)
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| Quiz |
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The Nature Biotechnology 2000 Millennial quiz pp108 - 109
John Hodgson
&
Andrew Marshall
doi:10.1038/71788
Full text | PDF
(198K)
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| New Products |
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New Products p110
doi:10.1038/71809
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(181K)
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| Industry Trends |
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Malaria pp111 - 112
Aris Persidis
doi:10.1038/71816
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(97K)
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| Index | Top |
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1999 Subject index — Volume 17 pp113 - 118
doi:10.1038/71819
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(128K)
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1999 Author index — Volume 17 pp118 - 121
doi:10.1038/71821
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(103K)
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