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Nature Biotechnology
ISSUE
April 1999, Volume 17 No 4
OpinionEditorial | Commentary | Correspondence | Errata
In BriefBusiness and Regulatory News | Research News | This Month in Biotechnology
AnalysisBusiness and Regulatory News | Research News and Views
Feature
Research Articles
ResourcesPatents | In the Laboratory | Book Review | People | New Products | Industry Trends
About the cover
Opinion Top
Editorial
Genetically modified muddle p311
doi:10.1038/7825
Full text | PDF (41K)
Commentary
Funding of human embryo research in the US p312
James Thomson
doi:10.1038/7826
Full text | PDF (33K)
Correspondence
Telomere-dependent senescence p313
David Kipling, David Wynford-Thomas, Chris J. Jones, Arne Akbar, Richard Aspinall, Silvia Bacchetti, Maria A. Blasco, Dominique Broccoli, Ron A. DePinho, Dylan R. Edwards, Rita B. Effros, Calvin B. Harley, Peter M. Lansdorp, Maarten H.K. Linskens, Karen R. Prowse, Robert F. Newbold, Alexey M. Olovnikov, E. Kenneth Parkinson, Graham Pawelec, Jan Pontén, Sydney Shall, Mark Zijlmans & Richard G.A. Faragher
doi:10.1038/7837
Full text | PDF (88K)
Reply to "Telomere-dependent senescence" pp313 - 314
Harry Rubin
doi:10.1038/7829
Full text | PDF (99K)
Food safety regulations p314
Philip S. Angell
doi:10.1038/7830
Full text | PDF (35K)
Errata
Errata p314
doi:10.1038/7831
Full text | PDF (35K)
In Brief Top
Business and Regulatory News
DuPont bolsters life sciences p315
Emma Dorey
doi:10.1038/7832
Full text | PDF (41K)
India faces GM cotton delay p315
KS Jayaraman
doi:10.1038/7833
Full text | PDF (41K)
Stem cell ruling protests p315
Vicki Brower
doi:10.1038/7834
Full text | PDF (41K)
EPA sued over Bt crops p315
Alan Dove
doi:10.1038/7835
Full text | PDF (41K)
Food fight in Colombia p315
Jeffrey Fox
doi:10.1038/7836
Full text | PDF (41K)
New initiative to promote UK technology start-ups p315
Adam Michael
doi:10.1038/7837
Full text | PDF (41K)
Budget boost for UK biotech p316
Adam Michael
doi:10.1038/7839
Full text | PDF (32K)
Pharmanex wins round two p316
Vicki Brower
doi:10.1038/7840
Full text | PDF (32K)
Gilead acquires NeXstar p316
Emma Dorey
doi:10.1038/7841
Full text | PDF (32K)
Swiss ban xenotransplants p316
Ingeborg Fürst
doi:10.1038/7842
Full text | PDF (32K)
Research collaborations p316
Adam Michael
doi:10.1038/7843
Full text | PDF (32K)
Research News
Adenovirus vector gutted p317
Alan Dove
doi:10.1038/7845
Full text | PDF (66K)
IL-2 boosts cancer vaccine p317
Alan Dove
doi:10.1038/7846
Full text | PDF (66K)
Haploinsufficiency drug screen p317
Alan Dove
doi:10.1038/7847
Full text | PDF (66K)
Mix and match Streptomyces p317
Andrew Marshall
doi:10.1038/7849
Full text | PDF (66K)
Drug targeting looks inward p317
Alan Dove
doi:10.1038/7850
Full text | PDF (66K)
This Month in Biotechnology
Dye transfer: all washed up p318
Robert Frederickson
doi:10.1038/7851
Full text | PDF (117K)
Mirror, mirror p318
Robert Frederickson
doi:10.1038/7853
Full text | PDF (117K)
Tumor gene medicine p318
Robert Frederickson
doi:10.1038/7854
Full text | PDF (117K)
Discriminating SNPs p318
Robert Frederickson
doi:10.1038/7856
Full text | PDF (117K)
Knocking out the herpesvirus genome p318
Natalie Dewitt
doi:10.1038/7858
Full text | PDF (117K)
Dosing Gene Therapy for Parkinson's Disease p318
Natalie Dewitt
doi:10.1038/7859
Full text | PDF (117K)
Gene flow from crops to weeds p318
Natalie Dewitt
doi:10.1038/7861
Full text | PDF (117K)
Live Imaging of Tumors p318
Natalie Dewitt
doi:10.1038/7862
Full text | PDF (117K)
Producing collagen in a mammary bioreactor p318
Natalie Dewitt
doi:10.1038/7864
Full text | PDF (117K)
Getting the bugs out p318
Robert Frederickson
doi:10.1038/7865
Full text | PDF (117K)
Analysis Top
Business and Regulatory News
FDA slow to encourage lupus drugs p319
David Webber
doi:10.1038/7866
Full text | PDF (58K)
Japan pushes to capitalize on biotechnology pp320 - 321
Asako Saegusa
doi:10.1038/7868
Full text | PDF (53K)
European Parliament considers release of GMOs p321
Barbara Nasto
doi:10.1038/7870
Full text | PDF (33K)
Glaxo's antiviral ills not deemed contagious pp322 - 323
Alan Dove
doi:10.1038/7871
Full text | PDF (55K)
Adjusting FDA policies to address bioterrorist threat pp323 - 324
Jeffrey L. Fox
doi:10.1038/7873
Full text | PDF (56K)
FDA's interferon-beta decision reignites orphan debate pp324 - 325
Andrew Marshall
doi:10.1038/7875
Full text | PDF (42K)
Complaints raised over restricted microarray access pp325 - 326
Jeffrey L. Fox
doi:10.1038/7876
Full text | PDF (60K)
Genentech enlightens other angiogenesis programs pp326 - 327
Vicki Brower
doi:10.1038/7877
Full text | PDF (57K)
Research News and Views
Debugging expression screening pp329 - 330
Philip L. Felgner & Xiaowu Liang
doi:10.1038/7880
Full text | PDF (325K)
See also: Research Article by Sykes & Johnston
Transgene escape and transplastomics pp330 - 331
Dean Chamberlain & C. Neal Stewart Jr.
doi:10.1038/7882
Full text | PDF (297K)
See also: Research Article by Scott & Wilkinson
Transposing BACs to the future pp332 - 333
Craig A. Strathdee
doi:10.1038/7884
Full text | PDF (358K)
See also: Research Article by Brune et al.
Colorless green ideas. . . pp333 - 334
Matthew Tobin, Joseph A. Affholter, Willem P.C. Stemmer & Jeremy Minshull
doi:10.1038/7886
Full text | PDF (90K)
See also: Research Article by Cherry et al.
Bioartificial organs transplanted from research to reality pp335 - 336
David Hunkeler
doi:10.1038/7888
Full text | PDF (107K)
The body as a manufacturer of endostatin pp336 - 337
Ronald G. Crystal
doi:10.1038/7890
Full text | PDF (53K)
See also: Research Article by Blezinger et al.
Feature Top
Encapsulating the right chemistry pp339 - 341
Bijal Trivedi
doi:10.1038/7892
Abstract | Full text | PDF (287K)
Research Articles Top
Systemic inhibition of tumor growth and tumor metastases by intramuscular administration of the endostatin gene pp343 - 348
Paul Blezinger, Jijun Wang, Margaret Gondo, Abraham Quezada, Dorothy Mehrens, Martha French, Arun Singhal, Sean Sullivan, Alain Rolland, Rob Ralston & Wang Min
doi:10.1038/7895
Abstract | Full text | PDF (246K)
See also: Analysis by Crystal
A single adenovirus vector mediates doxycycline-controlled expression of tyrosine hydroxylase in brain grafts of human neural progenitors pp349 - 354
Olga Corti, Olivier Sabaté, Philippe Horellou, Philippe Colin, Sylvie Dumas, Delphine Buchet, Marie-Hélène Buc-Caron & Jacques Mallet
doi:10.1038/7901
Abstract | Full text | PDF (395K)
Linear expression elements: a rapid, in vivo, method to screen for gene functions pp355 - 359
Kathryn F. Sykes & Stephen Albert Johnston
doi:10.1038/7908
Abstract | Full text | PDF (94K)
See also: Analysis by Felgner & Liang
Rapid identification of essential and nonessential herpesvirus genes by direct transposon mutagenesis pp360 - 364
Wolfram Brune, Carine Ménard, Urs Hobom, Stefan Odenbreit, Martin Messerle & Ulrich H. Koszinowski
doi:10.1038/7914
Abstract | Full text | PDF (864K)
See also: Analysis by Strathdee
Single nucleotide polymorphic discrimination by an electronic dot blot assay on semiconductor microchips pp365 - 370
Patrick N. Gilles, David J. Wu, Charles B. Foster, Patrick J. Dillon & Stephen J. Chanock
doi:10.1038/7921
Abstract | Full text | PDF (219K)
Chiral discrimination using an immunosensor pp371 - 374
Oliver Hofstetter, Heike Hofstetter, Meir Wilchek, Volker Schurig & Bernard S. Green
doi:10.1038/7927
Abstract | Full text | PDF (86K)
In vivo imaging of tumors with protease-activated near-infrared fluorescent probes pp375 - 378
Ralph Weissleder, Ching-Hsuan Tung, Umar Mahmood & Alexei Bogdanov Jr.
doi:10.1038/7933
Abstract | Full text | PDF (251K)
Directed evolution of a fungal peroxidase pp379 - 384
Joel R. Cherry, Michael H. Lamsa, Palle Schneider, Jesper Vind, Allan Svendsen, Aubrey Jones & Anders H. Pedersen
doi:10.1038/7939
Abstract | Full text | PDF (402K)
See also: Analysis by Tobin et al.
Expression of an engineered form of recombinant procollagen in mouse milk pp385 - 389
David C.A. John, Rod Watson, Alexander J. Kind, Ann R. Scott, Karl E. Kadler & Neil J. Bulleid
doi:10.1038/7945
Abstract | Full text | PDF (118K)
Low probability of chloroplast movement from oilseed rape (Brassica napus) into wild Brassica rapa pp390 - 392
Susan E. Scott & Mike J. Wilkinson
doi:10.1038/7952
Abstract | Full text | PDF (58K)
See also: Analysis by Chamberlain & Stewart
Errata to "Plants ectopically expressing the iron-binding protein, ferritin, are tolerant to oxidative damage and pathogens" p393
doi:10.1038/7975
Full text | PDF (120K)
Errata to "Targeted adeno-associated virus vector transduction of nonpermissive cells mediated by a bispecific F(ab ´gamma) 2 antibody" p393
doi:10.1038/7976
Full text | PDF (120K)
Resources Top
Patents
The patentability of algorithms p395
Tony D. Alexander
doi:10.1038/7955
Abstract | Full text | PDF (46K)
Recent patents in stem cell research p396
doi:10.1038/7957
Full text | PDF (27K)
In the Laboratory
Selection of high-affinity phage antibodies from phage display libraries pp397 - 399
Robert de Bruin, Kees Spelt, Joseph Mol, Ronald Koes & Francesca Quattrocchio
doi:10.1038/7959
Abstract | Full text | PDF (253K)
Book Review
Conversations in cloning p400
Reviewed by: Harold T. Shapiro
doi:10.1038/7963
Full text | PDF (69K)
People
People p401
doi:10.1038/7965
Full text | PDF (37K)
New Products
New products p402
doi:10.1038/7967
Full text | PDF (104K)
Industry Trends
Antisense therapeutics pp403 - 404
Aris Persidis
doi:10.1038/7973
Full text | PDF (43K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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