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| Opinion |  Top |
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| Editorials |
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Killer potatoes: Where's the data? p207
doi:10.1038/6906
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More gods and monsters p207
doi:10.1038/6907
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| Commentary |
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Feeding the world, harmoniously p208
Tom Crompton
doi:10.1038/6908
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(55K)
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Keeping the biotechnology of antisense in context p209
C.A. Stein
doi:10.1038/6909
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(57K)
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| Correspondence |
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Shorter is better p210
M. Raafat El-Gewely
doi:10.1038/6910
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(69K)
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Spin science p210
Ronald W. Eastman
doi:10.1038/6911
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(69K)
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| Errata |
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Erratum p210
doi:10.1038/6912
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| In Brief | Top |
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| Business and Regulatory News |
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Warner-Lambert acquires speculative Agouron pipeline p211
Emma Dorey
doi:10.1038/6913
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IPOs increase in Europe p211
Adam Michael
doi:10.1038/6914
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(115K)
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Cortech relists p211
Vicki Brower
doi:10.1038/6915
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(115K)
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India sequences chickpea p211
KS Jayaraman
doi:10.1038/6917
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(115K)
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Shaman switches gears p211
Vicki Brower
doi:10.1038/6919
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(115K)
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Marimastat fails again p212
Adam Michael
doi:10.1038/6920
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Japan easy on gene therapy p212
Asako Saegusa
doi:10.1038/6921
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First US−German start-up p212
Adam Michael
doi:10.1038/6922
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Entremed's stock seesaws p212
Emma Dorey
doi:10.1038/6923
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New plant to desulfurize oil p212
Stephen Cass
doi:10.1038/6924
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Research collaborations p212
doi:10.1038/6925
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| Research News |
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Controlled-release microchip p213
Margret Einarson
doi:10.1038/6927
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Muscling in on bone formation p213
LeeAnn Leshko
doi:10.1038/6929
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Reprogramming neural stem cells p213
Alex Castellino
doi:10.1038/6930
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(68K)
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Sizing up DNA p213
LeeAnn Leshko
doi:10.1038/6932
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(68K)
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Priming axon regeneration p213
Aseem Ansari
doi:10.1038/6933
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| This Month in Biotechnology |
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Antitumor vaccines with punch p214
Natalie DeWitt
doi:10.1038/6934
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Building better promoters p214
Robert Frederickson
doi:10.1038/6936
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Invading diagnostics p214
Robert Frederickson
doi:10.1038/6937
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Stress relief for plants p214
Robert Frederickson
doi:10.1038/6938
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Iron-fortified rice p214
Natalie DeWitt
doi:10.1038/6940
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A synthetic IL-10 mimic p214
Natalie DeWitt
doi:10.1038/6942
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Evolving thymidine kinase p214
Natalie DeWitt
doi:10.1038/6943
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Stealthy RNases p214
Robert Frederickson
doi:10.1038/6945
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Making antibodies more human p214
Natalie DeWitt
doi:10.1038/6947
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Reprogramming messages p214
Robert Frederickson
doi:10.1038/6948
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(123K)
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| Analysis | Top |
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| Business and Regulatory News |
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Stem cell transformations proliferate p215
Vicki Brower
doi:10.1038/6950
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(68K)
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UK government supports biotech pp215 - 216
Adam Michael
doi:10.1038/6951
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USDA appeases organic lobby p217
Jeffrey L. Fox
doi:10.1038/6953
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Synergen lineage may finally pay off pp217 - 218
Joseph Alper
doi:10.1038/6954
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(71K)
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Overview of FY 2000 US federal budget request p219
Jeffrey L. Fox
doi:10.1038/6955
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Cancer Pathways' target not validated by clinical results p220
Mark Ratner
doi:10.1038/6956
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Pharma strategies extend drug lives pp220 - 221
Debra Robertson
doi:10.1038/6957
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Return of the Neuer Markt p222
Ingeborg Fürst
doi:10.1038/6958
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| Research News and Views |
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A new routine in molecular gymnastics pp223 - 224
Ryszard Kole
doi:10.1038/6960
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(112K)
See also: Research Article by Puttaraju et al. |
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Piecing together more efficient gene expression pp224 - 225
Nikunj V. Somia, Tal Kafri
& Inder M. Verma
doi:10.1038/6962
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(86K)
See also: Research Article by Li et al. |
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Extending genetic vaccines with chemokines pp226 - 227
Thomas Kipps
& Robert Mendoza
doi:10.1038/6964
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(87K)
See also: Research Article by Biragyn et al. |
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Smartbombs and cloaking devices pp227 - 228
Richard W. Wagner
& Dasa Lipovsek
doi:10.1038/6966
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(202K)
See also: Research Article by Suzuki et al. |
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DREB takes the stress out of growing up pp229 - 230
Nicholas Smirnoff
& John A. Bryant
doi:10.1038/6968
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(88K)
See also: Research Article by Kasuga et al. |
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Pumping iron pp230 - 231
Michael R. Sussman
doi:10.1038/6970
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(82K)
See also: Research Article by Goto et al. |
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| Features | Top |
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Proteomics: translating genomics into products? pp233 - 236
Alan Dove
doi:10.1038/6972
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(256K)
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Drug approval in Europe pp237 - 240
Gary Walsh
doi:10.1038/6977
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(90K)
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| Research Articles | Top |
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Synthetic muscle promoters: activities exceeding naturally occurring
regulatory sequences pp241 - 245
Xuyang Li, Eric M. Eastman, Robert J. Schwartz
& Ruxandra Draghia-Akli
doi:10.1038/6981
Abstract | Full text | PDF
(414K)
See also: Analysis by Somia et al. |
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Spliceosome-mediated RNA trans-splicing as a tool for gene therapy
pp246 - 252
M. Puttaraju, Sharon F. Jamison, S. Gary Mansfield, Mariano A. Garcia-Blanco
& Lloyd G. Mitchell
doi:10.1038/6986
Abstract | Full text | PDF
(227K)
See also: Analysis by Kole |
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Genetic fusion of chemokines to a self tumor antigen induces protective,
T-cell dependent antitumor immunity pp253 - 258
Arya Biragyn, Kenji Tani, Michael C. Grimm, Steven Weeks
& Larry W. Kwak
doi:10.1038/6995
Abstract | Full text | PDF
(284K)
See also: Analysis by Kipps & Mendoza |
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Directed evolution of thymidine kinase for AZT phosphorylation using
DNA family shuffling pp259 - 264
Fred C. Christians, Leonardo Scapozza, Andreas Crameri, Gerd Folkers
& Willem P.C. Stemmer
doi:10.1038/7003
Abstract | Full text | PDF
(712K)
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Engineering receptor-mediated cytotoxicity into human ribonucleases by
steric blockade of inhibitor interaction pp265 - 270
Motoshi Suzuki, Shailendra K. Saxena, Ester Boix, Robert J. Prill, Veena M. Vasandani, Jane E. Ladner, Cynthia Sung
& Richard J. Youle
doi:10.1038/7010
Abstract | Full text | PDF
(242K)
See also: Analysis by Wagner & Lipovsek |
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A synthetic mimic of a discontinuous binding site on interleukin-10 pp271 - 275
Ulrich Reineke, Robert Sabat, Rolf Misselwitz, Heinz Welfle, Hans-Dieter Volk
& Jens Schneider-Mergener
doi:10.1038/7018
Abstract | Full text | PDF
(194K)
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A recombinant, fully human monoclonal antibody with antitumor activity
constructed from phage-displayed antibody fragments pp276 - 281
Gerwin A. Huls, Ingmar A.F.M. Heijnen, Maria E. Cuomo, Jacob C. Koningsberger, Luus Wiegman, Edwin Boel, Anne-Reneé van der Vuurst de Vries, Sabine A.J. Loyson, Wijnand Helfrich, Gerard P. van Berge Henegouwen, Marja van Meijer, John de Kruif
& Ton Logtenberg
doi:10.1038/7023
Abstract | Full text | PDF
(190K)
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Iron fortification of rice seed by the soybean ferritin gene pp282 - 286
Fumiyuki Goto, Toshihiro Yoshihara, Naoki Shigemoto, Seiichi Toki
& Fumio Takaiwa
doi:10.1038/7029
Abstract | Full text | PDF
(174K)
See also: Analysis by Sussman |
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Improving plant drought, salt, and freezing tolerance by gene transfer
of a single stress-inducible transcription factor pp287 - 291
Mie Kasuga, Qiang Liu, Setsuko Miura, Kazuko Yamaguchi-Shinozaki
& Kazuo Shinozaki
doi:10.1038/7036
Abstract | Full text | PDF
(292K)
See also: Analysis by Smirnoff & Bryant |
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Polymorphism identification and quantitative detection of genomic DNA
by invasive cleavage of oligonucleotide probes pp292 - 296
Victor Lyamichev, Andrea L. Mast, Jeff G. Hall, James R. Prudent, Michael W. Kaiser, Tsetska Takova, Robert W. Kwiatkowski, Tamara J. Sander, Monika de Arruda, David A. Arco, Bruce P. Neri
& Mary Ann D. Brow
doi:10.1038/7044
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(158K)
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| Resources | Top |
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| Patents |
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Have you bargained away patent rights? pp297 - 298
Breffni Baggot
doi:10.1038/7050
Abstract | Full text | PDF
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Recent antibody-related patents p299
doi:10.1038/7052
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| In the Laboratory |
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Displacement chromatography for biopolymer separation pp300 - 302
Ruth Freitag
doi:10.1038/7054
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| Book Review |
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Electric genes p303
Reviewed by: Terry Gaasterland
doi:10.1038/7061
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| Internet |
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Web PCR p304
Stacey McCann
doi:10.1038/7063
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(76K)
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| People |
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People p305
doi:10.1038/7065
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(58K)
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| New Products |
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New products p306
doi:10.1038/7067
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(174K)
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| Industry Trends |
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Mental disorder drug discovery pp307 - 309
Aris Persidis
& Rachel M. Copen
doi:10.1038/7073
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