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Nature Biotechnology
ISSUE
November 1999, Volume 17 No 11
OpinionEditorials | Commentary | Correspondence
In BriefBusiness and Regulatory News | Research News | This Month in Biotechnology
AnalysisBusiness and Regulatory News | Research News and Views
Feature
Research Review
Research Articles
ResourcesPatents | In the Laboratory | People | New Products | Industry Trends
About the cover
Opinion Top
Editorials
Mixed messages p1041
doi:10.1038/14985
Full text | PDF (65K)
The truth about high-nicotine tobacco p1041
doi:10.1038/14986
Full text | PDF (65K)
Commentary
Substantial equivalence: Its uses and abuses pp1042 - 1043
Henry I. Miller
doi:10.1038/14987
Full text | PDF (83K)
International agbio consortium takes shape in Beijing p1044
Rafael Rangel-Aldao
doi:10.1038/14988
Full text | PDF (75K)
Bioartificial organs and acceptable risk p1045
David Hunkeler, Anthony M. Sun, Gregory S. Korbutt, Ray V. Rajotte, Ronald G. Gill, Riccardo Calafiore & Philippe Morel
doi:10.1038/14989
Full text | PDF (75K)
Correspondence
Protein tags enhance GFP folding in eukaryotic cells p1046
Andrea Sacchetti & Saverio Alberti
doi:10.1038/14990
Full text | PDF (107K)
Facts and hypotheses p1046
Edward Groth III
doi:10.1038/14992
Full text | PDF (107K)
Erratum p1046
doi:10.1038/14993
Full text | PDF (107K)
In Brief Top
Business and Regulatory News
The Lancet in GMO dispute p1047
John Hodgson
doi:10.1038/14994
Full text | PDF (66K)
Biosafety talks stall again p1047
Jeffrey Fox
doi:10.1038/14995
Full text | PDF (97K)
State needs more science p1047
John Hodgson
doi:10.1038/14996
Full text | PDF (97K)
Biotech booster site p1047
Emma Dorey
doi:10.1038/14997
Full text | PDF (97K)
GMO roundup p1047
John Hodgson
doi:10.1038/14998
Full text | PDF (97K)
Ag committee labors over labeling p1048
Jeffrey Fox
doi:10.1038/14999
Full text | PDF (64K)
Pro-GMO ministers sidelined p1048
John Hodgson
doi:10.1038/15000
Full text | PDF (64K)
Anti-GMO protest spreads to cloning p1048
doi:10.1038/15001
Full text | PDF (64K)
Genomics companies strike a deal p1048
doi:10.1038/15002
Full text | PDF (64K)
Biopharmaceutical sector performance, 3rd quarter 1999 p1048
doi:10.1038/15003
Full text | PDF (64K)
Initial public offerings, 3rd quarter 1999 p1048
doi:10.1038/15004
Full text | PDF (64K)
Biotech fundraising p1049
doi:10.1038/15005
Full text | PDF (65K)
India challenges gene piracy p1049
doi:10.1038/15006
Full text | PDF (65K)
Avanir prepares for sale p1049
Eric Niiler
doi:10.1038/15007
Full text | PDF (65K)
Research Collaborations p1049
doi:10.1038/15008
Full text | PDF (65K)
Research News
Stem cell gene delivery p1050
Alan Dove
doi:10.1038/15013
Full text | PDF (67K)
Deep pocket drugs p1050
Alan Dove
doi:10.1038/15014
Full text | PDF (67K)
Potent SOD mimic p1050
Andrew Marshall
doi:10.1038/15015
Full text | PDF (67K)
"Functional" proteomics? p1050
Robert Frederickson
doi:10.1038/15016
Full text | PDF (67K)
Microsequencer put through its paces p1050
Alan Dove
doi:10.1038/15017
Full text | PDF (67K)
This Month in Biotechnology
Just heat and. . .purify p1051
Robert Frederickson
doi:10.1038/15019
Full text | PDF (127K)
Gene knockouts in time and space p1051
Natalie DeWitt
doi:10.1038/15020
Full text | PDF (127K)
Potentiating biocontrol p1051
Natalie DeWitt
doi:10.1038/15021
Full text | PDF (127K)
Targeting tumor specificity p1051
Robert Frederickson
doi:10.1038/15022
Full text | PDF (127K)
A seminal bioreactor p1051
Robert Frederickson
doi:10.1038/15023
Full text | PDF (127K)
Therapeutic proteins get a sugar coating p1051
Natalie DeWitt
doi:10.1038/15024
Full text | PDF (127K)
Rebuilding blood vessels p1051
Robert Frederickson
doi:10.1038/15025
Full text | PDF (127K)
Antisense targets apoptosis p1051
Robert Frederickson
doi:10.1038/15026
Full text | PDF (127K)
GPCR biosensor chip p1051
Robert Frederickson
doi:10.1038/15027
Full text | PDF (127K)
Honey, I shrank the cell sorter p1051
Natalie DeWitt
doi:10.1038/15028
Full text | PDF (127K)
Keeping track of transgenes p1051
Natalie DeWitt
doi:10.1038/15029
Full text | PDF (127K)
Analysis Top
Business and Regulatory News
Anti-GM crop protesters increase activity in the US pp1053 - 1054
Jeffrey L. Fox
doi:10.1038/15032
Full text | PDF (83K)
Terminator technology temporarily terminated p1054
Eric Niiler
doi:10.1038/15034
Full text | PDF (73K)
New law to boost French biotech industry p1055
Sabine Louët
doi:10.1038/15035
Full text | PDF (69K)
EU plant programs wither under Framework V p1056
Marianne Heselmans
doi:10.1038/15036
Full text | PDF (88K)
Japan heats up rice sequencing p1057
Asako Saegusa
doi:10.1038/15038
Full text | PDF (69K)
Winners and losers in merger mania p1058
Eric Niiler
doi:10.1038/15039
Full text | PDF (72K)
Competition between flu drugs feverishly anticipated p1059
Vicki Glaser
doi:10.1038/15041
Full text | PDF (69K)
Research News and Views
Chipping away at GPCR function p1060
Kevin Beaumont & Paul Negulescu
doi:10.1038/15042
Full text | PDF (100K)
See also: Research Article by Bieri et al.
The burgeoning power of the shrinking laboratory pp1061 - 1062
J. Michael Ramsey
doi:10.1038/15044
Full text | PDF (117K)
See also: Research Article by Fu et al.
The right time and place for molecular scissors pp1062 - 1063
Lothar Hennighausen & Priscilla A. Furth
doi:10.1038/15046
Full text | PDF (106K)
See also: Research Article by Utomo et al.
Splicing and dicing apoptosis genes pp1064 - 1065
John C. Reed
doi:10.1038/15048
Full text | PDF (106K)
See also: Research Article by Taylor et al.
Protein therapy—delivery guaranteed pp1066 - 1067
Hagan Bayley
doi:10.1038/15050
Full text | PDF (108K)
Expanding the atomic description of biological systems pp1068 - 1069
Eduardo Horjales
doi:10.1038/15052
Full text | PDF (187K)
Feature Top
Moving agbiotech downstream pp1071 - 1074
David McElroy
doi:10.1038/15054
Abstract | Full text | PDF (316K)
Research Review Top
Advances in vaccine adjuvants pp1075 - 1081
Manmohan Singh & Derek O'Hagan
doi:10.1038/15058
Abstract | Full text | PDF (146K)
Research Articles Top
Remodeling of an acellular collagen graft into a physiologically responsive neovessel pp1083 - 1086
Tam Huynh, Ginger Abraham, James Murray, Kelvin Brockbank, Per-Otto Hagen & Susan Sullivan
doi:10.1038/15062
Abstract | Full text | PDF (267K)
Seminal vesicle production and secretion of growth hormone into seminal fluid pp1087 - 1090
Michael K. Dyck, Dominic Gagné, Mariette Ouellet, Jean-François Sénéchal, Edith Bélanger, Dan Lacroix, Marc-André Sirard & François Pothier
doi:10.1038/15067
Abstract | Full text | PDF (480K)
Temporal, spatial, and cell type−specific control of Cre-mediated DNA recombination in transgenic mice pp1091 - 1096
Ahmad R.H. Utomo, Alexander Yu. Nikitin & Wen-Hwa Lee
doi:10.1038/15073
Abstract | Full text | PDF (312K)
See also: Analysis by Hennighausen & Furth
Induction of endogenous Bcl-xS through the control of Bcl-x pre-mRNA splicing by antisense oligonucleotides pp1097 - 1100
Jennifer K. Taylor, Qing Qing Zhang, Jacqueline R. Wyatt & Nicholas M. Dean
doi:10.1038/15079
Abstract | Full text | PDF (328K)
See also: Analysis by Reed
Polymerizable Fab' antibody fragments for targeting of anticancer drugs pp1101 - 1104
Zheng-Rong Lu, Pavla Kopec caronková & Jindich Kopec caronek
doi:10.1038/15085
Abstract | Full text | PDF (497K)
Micropatterned immobilization of a G protein−coupled receptor and direct detection of G protein activation pp1105 - 1108
Christoph Bieri, Oliver P. Ernst, Stephan Heyse, Klaus Peter Hofmann & Horst Vogel
doi:10.1038/15090
Abstract | Full text | PDF (312K)
See also: Analysis by Beaumont & Negulescu
A microfabricated fluorescence-activated cell sorter pp1109 - 1111
Anne Y. Fu, Charles Spence, Axel Scherer, Frances H. Arnold & Stephen R. Quake
doi:10.1038/15095
Abstract | Full text | PDF (123K)
See also: Analysis by Ramsey
Purification of recombinant proteins by fusion with thermally-responsive polypeptides pp1112 - 1115
Dan E. Meyer & Ashutosh Chilkoti
doi:10.1038/15100
Abstract | Full text | PDF (298K)
Engineering Chinese hamster ovary cells to maximize sialic acid content of recombinant glycoproteins pp1116 - 1121
S. Weikert, D. Papac, J. Briggs, D. Cowfer, S. Tom, M. Gawlitzek, J. Lofgren, S. Mehta, V. Chisholm, N. Modi, S. Eppler, K. Carroll, S. Chamow, D. Peers, P. Berman & L. Krummen
doi:10.1038/15104
Abstract | Full text | PDF (203K)
Increased baculovirus susceptibility of armyworm larvae feeding on transgenic rice plants expressing an entomopoxvirus gene pp1122 - 1124
Tosihiko Hukuhara, Takahiko Hayakawa & Arman Wijonarko
doi:10.1038/15110
Abstract | Full text | PDF (167K)
Green fluorescent protein as a marker for expression of a second gene in transgenic plants pp1125 - 1129
Brian K. Harper, Stephen A. Mabon, Staci M. Leffel, Matthew D. Halfhill, Harold A. Richards, Kari A. Moyer & C. Neal Stewart Jr.
doi:10.1038/15114
Abstract | Full text | PDF (262K)
Resources Top
Patents
Patent office decisions strengthened by Supreme Court pp1131 - 1132
Breffni X. Baggot
doi:10.1038/15121
Abstract | Full text | PDF (62K)
Recent patents in electrophoresis p1133
doi:10.1038/15122
Full text | PDF (38K)
In the Laboratory
A high-density probe array sample preparation method using 10- to 100-fold fewer cells pp1134 - 1136
Mamatha Mahadevappa & Janet A. Warrington
doi:10.1038/15124
Full text | PDF (198K)
Quantitation of genetically modified organisms in food pp1137 - 1138
Philipp Hübner, Edgar Studer & Jürg Lüthy
doi:10.1038/15129
Full text | PDF (98K)
People
People p1139
doi:10.1038/15133
Full text | PDF (56K)
New Products
New Products p1140
doi:10.1038/15135
Full text | PDF (141K)
Industry Trends
Antibacterial and antifungal drug discovery pp1141 - 1142
Aris Persidis
doi:10.1038/15141
Full text | PDF (67K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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