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Nature Biotechnology
ISSUE
October 1999, Volume 17 No 10
OpinionEditorials | Commentary | Correspondence
In BriefBusiness and Regulatory News | Research News | This Month in Biotechnology
AnalysisBusiness and Regulatory News | Research News and Views
Feature
Research Articles
Errata
ResourcesPatents | In the Laboratory | People | New Products | Industry Trends
About the cover
Opinion Top
Editorials
A green light for debate p933
doi:10.1038/13586
Full text | PDF (61K)
A common green ground p933
doi:10.1038/13585
Full text | PDF (61K)
Commentary
Pharmaceutical biotechnology emerges in Mexico p934
Octavio T. Ramirez & Rodolfo Quintero
doi:10.1038/13587
Full text | PDF (67K)
Partnerships between patients, medicine, and the biotechnology industry p935
Alastair Kent & Erik Tambuyzer
doi:10.1038/13588
Full text | PDF (64K)
Defining epitopes: It's not as easy as it seems pp936 - 937
Neil S. Greenspan & Enrico Di Cera
doi:10.1038/13590
Full text | PDF (167K)
Correspondence
Erratum p938
doi:10.1038/13595
Full text | PDF (78K)
Public and private plant breeding p938
Steven C. Price
doi:10.1038/13594
Full text | PDF (78K)
Anti-Gal antibodies—where's the beef? p938
R. P. Junghans
doi:10.1038/13593
Full text | PDF (78K)
In Brief Top
Business and Regulatory News
GM roundup p939
John Hodgson
doi:10.1038/13601
Full text | PDF (75K)
GM-free Japan p939
Asako Saegusa
doi:10.1038/13600
Full text | PDF (75K)
US okays patent reform bill p939
Jeffrey Fox
doi:10.1038/13599
Full text | PDF (75K)
GMO panic affects drugs p939
Emma Dorey
doi:10.1038/13598
Full text | PDF (75K)
BBIOY starts recovery p939
Emma Dorey
doi:10.1038/13597
Full text | PDF (75K)
Cartoon p940
doi:10.1038/13607
Full text | PDF (88K)
Novartis to de-merge ag biz? p940
Ingeborg Spillman-Fuerst
doi:10.1038/13606
Full text | PDF (88K)
GFP: Kacs and dogs p940
John Hodgson
doi:10.1038/13605
Full text | PDF (88K)
Blow for UK biotech p940
Emma Dorey
doi:10.1038/13604
Full text | PDF (88K)
Bexxar rejected for now p940
Emma Dorey
doi:10.1038/13603
Full text | PDF (88K)
Good news for Amylin p940
Emma Dorey
doi:10.1038/13602
Full text | PDF (88K)
Research Collaborations p941
doi:10.1038/13612
Full text | PDF (60K)
Sequenom patent and deal p941
John Hodgson
doi:10.1038/13611
Full text | PDF (60K)
GenCom: a first for Japan p941
Asako Saegusa
doi:10.1038/13610
Full text | PDF (60K)
GMO backlash hits US p941
Emma Dorey
doi:10.1038/13609
Full text | PDF (60K)
Research News
Noisy protein sorting p942
Alan Dove
doi:10.1038/13618
Full text | PDF (73K)
Mustard plant passes the salt p942
Alan Dove
doi:10.1038/13617
Full text | PDF (73K)
Double dose cancer treatment p942
Alan Dove
doi:10.1038/13616
Full text | PDF (73K)
Electric mismatch detection p942
Andrew Marshall
doi:10.1038/13615
Full text | PDF (73K)
Proteins break on through to the other side p942
Andrew Marshall
doi:10.1038/13614
Full text | PDF (73K)
This Month in Biotechnology
Microbial Signaling p943
Robert Frederickson
doi:10.1038/13630
Full text | PDF (81K)
Cheaper chips? p943
Natalie DeWitt
doi:10.1038/13629
Full text | PDF (81K)
GFP puts on the red light p943
Robert Frederickson
doi:10.1038/13628
Full text | PDF (81K)
No pain, no gain p943
Natalie DeWitt
doi:10.1038/13627
Full text | PDF (81K)
Gene repair redoubles its efforts p943
Robert Frederickson
doi:10.1038/13626
Full text | PDF (81K)
SPOTting differences in peptide reactivity p943
Robert Frederickson
doi:10.1038/13625
Full text | PDF (81K)
Just one word—plastics p943
Natalie DeWitt
doi:10.1038/13624
Full text | PDF (81K)
Zapping ocular angiogenesis p943
Natalie DeWitt
doi:10.1038/13623
Full text | PDF (81K)
A neuritogenic synthetic peptide p943
Natalie DeWitt
doi:10.1038/13622
Full text | PDF (81K)
Mass spec sees double p943
Robert Frederickson
doi:10.1038/13621
Full text | PDF (81K)
Detoxifying plant pathogens p943
Robert Frederickson
doi:10.1038/13620
Full text | PDF (81K)
Analysis Top
Business and Regulatory News
EU food agency circles round biotech p945
John Hodgson
doi:10.1038/13634
Full text | PDF (78K)
Asia calls for united approach to commerce pp946 - 947
Asako Saegusa
doi:10.1038/13636
Full text | PDF (133K)
Michigan spends $1 billion on "life sciences corridor" pp947 - 948
Alka Agrawal
doi:10.1038/13638
Full text | PDF (92K)
Clinton and Congress weigh in on biomass p949
Alan Dove
doi:10.1038/13640
Full text | PDF (104K)
Giga-speed bioinformatics to power Genome Canada p950
Brian Hoyle
doi:10.1038/13642
Full text | PDF (65K)
Curagen lays down markers, 120,000 of them p951
John Hodgson
doi:10.1038/13643
Full text | PDF (63K)
Research News and Views
Cheap DNA arrays—it's not all smoke and mirrors p953
Alan P. Blanchard & Stephen H. Friend
doi:10.1038/13644
Full text | PDF (99K)
See also: Research Article by Singh-Gasson et al.
Quantitative proteomics? pp954 - 955
Matthias Mann
doi:10.1038/13646
Full text | PDF (97K)
See also: Research Article by Gygi et al.
Rosy dawn for fluorescent proteins pp956 - 957
Roger Y. Tsien
doi:10.1038/13648
Full text | PDF (135K)
See also: Research Article by Matz et al.
Plants and microorganisms—listening in on the conversation pp958 - 959
Noel T. Keen
doi:10.1038/13650
Full text | PDF (127K)
See also: Research Article by Fray et al.  | Research Article by Zhang et al.
Green chemistry yields a better plastic pp960 - 961
Yves Poirier
doi:10.1038/13652
Full text | PDF (109K)
See also: Research Article by Slater et al.
Feature Top
Tumor angiogenesis—new drugs on the block pp963 - 968
Vicki Brower
doi:10.1038/13654
Abstract | Full text | PDF (131K)
Research Articles Top
Fluorescent proteins from nonbioluminescent Anthozoa species pp969 - 973
Mikhail V. Matz, Arkady F. Fradkov, Yulii A. Labas, Aleksandr P. Savitsky, Andrey G. Zaraisky, Mikhail L. Markelov & Sergey A. Lukyanov
doi:10.1038/13657
Abstract | Full text | PDF (525K)
Maskless fabrication of light-directed oligonucleotide microarrays using a digital micromirror array pp974 - 978
Sangeet Singh-Gasson, Roland D. Green, Yongjian Yue, Clark Nelson, Fred Blattner, Michael R. Sussman & Franco Cerrina
doi:10.1038/13664
Abstract | Full text | PDF (570K)
See also: Analysis by Blanchard & Friend
Cyclic mechanical strain regulates the development of engineered smooth muscle tissue pp979 - 983
Byung-Soo Kim, Janeta Nikolovski, Jeffrey Bonadio & David J. Mooney
doi:10.1038/13671
Abstract | Full text | PDF (829K)
Selective targeting and photocoagulation of ocular angiogenesis mediated by a phage-derived human antibody fragment pp984 - 988
Manfred Birchler, Francesca Viti, Luciano Zardi, Bernhard Spiess & Dario Neri
doi:10.1038/13679
Abstract | Full text | PDF (329K)
Correction of chromosomal point mutations in human cells with bifunctional oligonucleotides pp989 - 993
Kenneth W. Culver, Wang-Ting Hsieh, Yentram Huyen, Vivian Chen, Jilan Liu, Yuri Khripine & Alexander Khorlin
doi:10.1038/13684
Abstract | Full text | PDF (158K)
Quantitative analysis of complex protein mixtures using isotope-coded affinity tags pp994 - 999
Steven P. Gygi, Beate Rist, Scott A. Gerber, Frantisek Turecek, Michael H. Gelb & Ruedi Aebersold
doi:10.1038/13690
Abstract | Full text | PDF (495K)
See also: Analysis by Mann
Identification of a neuritogenic ligand of the neural cell adhesion molecule using a combinatorial library of synthetic peptides pp1000 - 1005
Lars C.B. Rønn, Marianne Olsen, Søren Østergaard, Vladislav Kiselyov, Vladimir Berezin, Marie T. Mortensen, Mathilde H. Lerche, Peter H. Jensen, Vladislav Soroka, Jane L. Saffells, Patrick Doherty, Flemming M. Poulsen, Elisabeth Bock & Arne Holm
doi:10.1038/13697
Abstract | Full text | PDF (715K)
Amino acid specificity of glycation and protein−AGE crosslinking reactivities determined with a dipeptide SPOT library pp1006 - 1010
Gerald Münch, Dorothee Schicktanz, Andrea Behme, Manfred Gerlach, Peter Riederer, Dieter Palm & Reinhard Schinzel
doi:10.1038/13704
Abstract | Full text | PDF (387K)
Metabolic engineering of Arabidopsis and Brassica for poly(3-hydroxybutyrate-
co-3-hydroxyvalerate) copolymer production
 pp1011 - 1016
Steven Slater, Timothy A. Mitsky, Kathryn L. Houmiel, Ming Hao, Steven E. Reiser, Nancy B. Taylor, Minhtien Tran, Henry E. Valentin, Damian J. Rodriguez, Deborah A. Stone, Stephen R. Padgette, Ganesh Kishore & Kenneth J. Gruys
doi:10.1038/13711
Abstract | Full text | PDF (520K)  | Supplementary Information
See also: Analysis by Poirier
Plants genetically modified to produce N-acylhomoserine lactones communicate with bacteria pp1017 - 1020
Rupert G. Fray, John P. Throup, Mavis Daykin, Andrew Wallace, Paul Williams, Gordon S.A.B. Stewart & Donald Grierson
doi:10.1038/13717
Abstract | Full text | PDF (205K)
See also: Analysis by Keen
Engineered detoxification confers resistance against a pathogenic bacterium  pp1021 - 1024
Lianhui Zhang, Jingling Xu & Robert G. Birch
doi:10.1038/13721
Abstract | Full text | PDF (384K)
See also: Analysis by Keen
Errata Top
Erratum: Determining the influence of structure on hybridization using oligonucleotide arrays p1025
doi:10.1038/13726
Full text | PDF (96K)
Erratum: Inducible isopentenyl transferase as a high-efficiency marker for plant transformation p1025
doi:10.1038/13728
Full text | PDF (96K)
Resources Top
Patents
Research tool patents and the experimental use exemption—a no-win situation? pp1027 - 1028
Philippe Ducor
doi:10.1038/13729
Abstract | Full text | PDF (66K)
Recent patents in gene regulation and expression p1029
doi:10.1038/13730
Full text | PDF (40K)
In the Laboratory
A generic protein purification method for protein complex characterization and proteome exploration pp1030 - 1032
Guillaume Rigaut, Anna Shevchenko, Berthold Rutz, Matthias Wilm, Matthias Mann & Bertrand Séraphin
doi:10.1038/13732
Abstract | Full text | PDF (264K)
Noninvasive visualization of tumors in rodent dorsal skin window chambers pp1033 - 1035
Qian Huang, Siqing Shan, Rod D. Braun, Jennifer Lanzen, Gopal Anyrhambatla, Garheng Kong, Michael Borelli, Peter Corry, Mark W. Dewhirst & Chuan-Yuan Li
doi:10.1038/13736
Abstract | Full text | PDF (160K)
People
People p1036
doi:10.1038/13740
Full text | PDF (55K)
New Products
New Products p1037
doi:10.1038/13742
Full text | PDF (125K)
Industry Trends
Autoimmune disease drug discovery p1038
Aris Persidis
doi:10.1038/13748
Full text | PDF (70K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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