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| Opinion |  Top |
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| Editorials |
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Creating and shaping the marketplace? p597
doi:10.1038/nbt0797-597a
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Chickens, cows, bulls, and bears p597
doi:10.1038/nbt0797-597b
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| Commentary |
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Research Funding: Clinical investigators: The driving force behind drug discovery pp598 - 599
Jordan U. Gutterman
doi:10.1038/nbt0797-598
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US Federal Legislation: Clinton's cloning ban may threaten genetic research p600
Russ Hoyle
doi:10.1038/nbt0797-600
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| In Brief | Top |
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| Business and Regulatory News |
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Business & Regulatory News pp601 - 602
doi:10.1038/nbt0797-601
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| Research News |
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Research News p604
doi:10.1038/nbt0797-604
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| This Month in Biotechnology |
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This Month In Nature Biotechnology p605
doi:10.1038/nbt0797-605
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| Analysis | Top |
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| Business and Regulatory News |
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Roche−Mannheim: Cornering the diagnosis-led healthcare market pp607 - 608
Vicki Brower
doi:10.1038/nbt0797-607
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Bavarian concerns about BM takeover p608
Ingeborg Fürst
doi:10.1038/nbt0797-608
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US bioethicists say continue human cloning moratorium p609
Jeffrey L. Fox
doi:10.1038/nbt0797-609a
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Europe/Japan face up to legal hurdles to cloning pp609 - 610
Adam Michael
doi:10.1038/nbt0797-609b
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Biotech unruffled by setbacks pp610 - 611
Vicki Glaser
doi:10.1038/nbt0797-610
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"DARPAesque" risk in biological warfare programs pp611 - 612
Jeffrey L. Fox
doi:10.1038/nbt0797-611
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(331K)
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US military takes up phytoremediation p612
Jeffrey L. Fox
doi:10.1038/nbt0797-612a
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(141K)
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Hemispherx: 300 patents, 20 staff pp612 - 613
Ken Chahine
doi:10.1038/nbt0797-612b
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India fears patent and ethics abuses p613
Udo Schuklenk
doi:10.1038/nbt0797-613
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Millennium exploits retained right with new venture p614
Emma Dorey
doi:10.1038/nbt0797-614
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(193K)
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MRA agreement signals start of global harmonization p615
John Hodgson
doi:10.1038/nbt0797-615
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(186K)
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| Research News |
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Antibodies live long and prosper p617
Lutz Riechmann
& Philipp Holliger
doi:10.1038/nbt0797-617
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(164K)
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Happy coupling: Recruiting both antigen and effector function pp618 - 619
Douglas Fearon
doi:10.1038/nbt0797-618
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(273K)
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Accessories for naked DNA vaccines pp619 - 620
Hyam I. Levitsky
doi:10.1038/nbt0797-619
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Liposomal gene delivery: A complex package pp620 - 621
Leaf Huang
& Song Li
doi:10.1038/nbt0797-620
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Surface warfare against pathogens using mucosal vaccines pp622 - 623
John D. Clements
doi:10.1038/nbt0797-622
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Entering the domain of neurotrophin binding pp623 - 624
Barbara L. Hempstead
& Moses V. Chao
doi:10.1038/nbt0797-623
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(275K)
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Evolution goes for GOLD in silico p624
Clare Sansom
doi:10.1038/nbt0797-624
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| Feature | Top |
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Molecular technologies for biodiversity evaluation: Opportunities and challenges pp625 - 628
Angela Karp, Keith J. Edwards, Mike Bruford, Stephan Funk, Ben Vosman, Michele Morgante, Ole Seberg, Antoine Kremer, Pierre Boursot, Peter Arctander, Diethard Tautz
& Godfrey M. Hewitt
doi:10.1038/nbt0797-625
Abstract + references | PDF
(962K)
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| Research Articles | Top |
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Complement recruitment using bispecific diabodies pp629 - 631
Roland E. Kontermann, Mark G. Wing
& Greg Winter
doi:10.1038/nbt0797-629
Abstract + references | PDF
(471K)
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Retargeting serum immunoglobulin with bispecific diabodies pp632 - 636
Philipp Holliger, Mark Wing, John D. Pound, Heribert Bohlen
& Greg Winter
doi:10.1038/nbt0797-632
Abstract + references | PDF
(735K)
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Increasing the serum persistence of an IgG fragment by random mutagenesis pp637 - 640
Victor Ghetie, Serguei Popov, Jozef Borvak, Caius Radu, Diana Matesoi, Corneliu Medesan, Raimund J. Ober
& E. Sally Ward
doi:10.1038/nbt0797-637
Abstract + references | PDF
(557K)
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Engineering of in vivo immune responses to DNA immunization via codelivery of costimulatory molecule genes pp641 - 646
Jong J. Kirn, Mark L. Bagarazzi, Neil Trivedi, Yin Hu, Ken Kazahaya, Darren M. Wilson, Richard Ciccarelli, Michael A. Chattergoon, Kesan Dang, Sundarasamy Mahalingam, Ara A. Chalian, Michael G. Agadjanyan, Jean D. Boyer, Bin Wang
& David B. Weiner
doi:10.1038/nbt0797-641
Abstract + references | PDF
(820K)
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Improved DNA: liposome complexes for increased systemic delivery and gene expression pp647 - 652
Nancy Smyth Templeton, Danilo D. Lasic, Peter M. Frederik, Helmut H. Strey, David D. Roberts
& George N. Pavlakis
doi:10.1038/nbt0797-647
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(905K)
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Oral vaccination of mice against tetanus with recombinant Lactococcus lactis pp653 - 657
Karen Robinson, Lisa M. Chamberlain, Karin M. Schofield, Jeremy M. Wells
& Richard W.F. Le Page
doi:10.1038/nbt0797-653
Abstract + references | PDF
(939K)
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Structure-based design and protein engineering of intersubunit disulfide bonds in gonadotropins pp658 - 662
Judith C. Heikoop, Paul van den Boogaart, John WM Mulders
& Peter D.J. Grootenhuis
doi:10.1038/nbt0797-658
Abstract + references | PDF
(664K)
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Design of stable biologically active recombinant lutropin analogs pp663 - 667
Vicenta Garcia-Campayo, Asomi Sato, Burkhard Hirsch, Tadashi Sugahara, Mesut Muyan, Aaron J.W. Hsueh
& Irving Boime
doi:10.1038/nbt0797-663
Abstract + references | PDF
(618K)
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Immunoglobulin-like domains define the nerve growth factor binding site of the TrkA receptor pp668 - 672
Paul H. Holden, Vipin Asopa, Alan G.S. Robertson, Anthony R. Clarke, Sue Tyler, Gavin S. Bennett, Susan D. Brain, Gordon K. Wilcock, Shelley J. Allen, Stephanie K.F. Smith
& David Dawbarn
doi:10.1038/nbt0797-668
Abstract + references | PDF
(663K)
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Regulation of the biological activity of glucagon-like peptide 2 in vivo by dipeptidyl peptidase IV pp673 - 677
Daniel J. Drucker, Qing Shi, Anna Crivici, Martin Sumner-Smith, Wendy Tavares, Mary Hill, Lorraine DeForest, Sari Cooper
& Patricia L. Brubaker
doi:10.1038/nbt0797-673
Abstract + references | PDF
(657K)
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| Resources | Top |
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| Patents |
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Combining legal and business strategies to develop combinatorial chemistry businesses pp679 - 681
David Abraham
doi:10.1038/nbt0797-679
Abstract | PDF
(656K)
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Patents applications in the area of combinational chemistry p682
doi:10.1038/nbt0797-682
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(298K)
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| WWW Guide |
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Steps to building the virtual laboratory pp683 - 684
Randy S. Haun
doi:10.1038/nbt0797-683
Abstract + references | PDF
(964K)
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| New Products |
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Looking at thermocyclers pp685 - 687
Riku Lähteenmdki
& John Hodgson
doi:10.1038/nbt0797-685
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(744K)
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New Products p688
doi:10.1038/nbt0797-688
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(172K)
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| Industry Trends |
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Critical issues in gene therapy commercialization pp689 - 690
Aris Persidis
& Michael S. Tomczyk
doi:10.1038/nbt0797-689
Abstract | PDF
(310K)
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| People |
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People p691
doi:10.1038/nbt0797-691
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(133K)
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