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| Opinion | Top |
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| Editorials |
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Does industry participation in research retard progress? p481 doi:10.1038/nbt0697-481a PDF
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Empirical antisense p481 doi:10.1038/nbt0697-481b PDF
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Collective unconsciousness p481 doi:10.1038/nbt0697-481c PDF
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| Commentary |
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Translating genomics information into therapeutics: A key role for oligonucleotides pp483 - 484 Ralph E. Christoffersen doi:10.1038/nbt0697-483 PDF
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Novartis' role in 21st century drug development p485 Daniel Vasella doi:10.1038/nbt0697-485 PDF
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The EPA's war on bioremediation p486 Henry Miller doi:10.1038/nbt0697-486 PDF
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Mycogen's Caulder steps down but not out p487 Russ Hoyle doi:10.1038/nbt0697-487 PDF
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Cloning our way to "the next level" p488 Stuart A. Newman doi:10.1038/nbt0697-488 References | PDF
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| In Brief | Top |
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| Business and Regulatory News |
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Agouron annexes Alanex pp489 - 491 doi:10.1038/nbt0697-489 PDF
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| Research News |
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Research news p492 doi:10.1038/nbt0697-492 PDF
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| This Month in Biotechnology |
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This Month in Nature Biotechnology p493 doi:10.1038/nbt0697-493 PDF
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| Analysis | Top |
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| Business and Regulatory News |
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Cephalon adds to clinical disappointment in 1997 pp495 - 496 Vicki Glaser doi:10.1038/nbt0697-495 PDF
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Amgen protects its billion dollar protein pp496 - 497 Ken Chahine doi:10.1038/nbt0697-496 PDF
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Gene activation and EPO p497 Sylvia Davidson doi:10.1038/nbt0697-497 PDF
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Antibiotech week raises tension over transgenic food pp499 - 500 Barbara Nasto
& Josh Lehrer doi:10.1038/nbt0697-499 PDF
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Whitehead consortium to develop new genome tools pp502 - 503 Vicki Brower doi:10.1038/nbt0697-502 PDF
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EPA issues, USDA amends respective biotech rules p503 Jeffrey L Fox doi:10.1038/nbt0697-503 PDF
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Industry-linked groups, geneticists, hoard data pp504 - 505 doi:10.1038/nbt0697-504 PDF
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Conflicts brewing as phage display gets complex p506 Vicki Glaser doi:10.1038/nbt0697-506 PDF
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Blood products have future despite recent setbacks p507 Vicki Brower doi:10.1038/nbt0697-507 PDF
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| Research News |
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Many are probed, but few are chosen p509 Francis C. Szoka Jr. doi:10.1038/nbt0697-509 References | PDF
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Addressing tumor blood vessels p510 Judah Folkman doi:10.1038/nbt0697-510 References | PDF
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A quick fix using random DNA amplification p511 Robert Haselkorn doi:10.1038/nbt0697-511 References | PDF
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Trick and treat: Toward peptide mimic vaccines pp512 - 513 Alexander R. Shikhman
& Madeleine W. Cunningham doi:10.1038/nbt0697-512 PDF
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Refolding with a piece of the ring pp514 - 515 Jonathan King doi:10.1038/nbt0697-514 References | PDF
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Rethinking the development of breast cancer pp517 - 518 Robert S. Schehr doi:10.1038/nbt0697-517 References | PDF
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Cancer researchers validate and pursue telomerase p518 Debra Robertson doi:10.1038/nbt0697-518 PDF
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| Features | Top |
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Antisense '97: A roundtable on the state of the industry pp519 - 524 doi:10.1038/nbt0697-519 Abstract | PDF
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Metabolic engineering and human disease pp525 - 528 Martin L. Yarmush
& François Berthiaume doi:10.1038/nbt0697-525 Abstract + references | PDF
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| Research Review | Top |
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From housekeeper to microsurgeon:
The diagnostic and therapeutic
potential of ribonucleases
pp529 - 536 Catherine H. Schein doi:10.1038/nbt0697-529 Abstract + references | PDF
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| Research Articles | Top |
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Selecting effective antisense reagents on combinatorial oligonucleotide arrays pp537 - 541 Natalie Milner, Kalim U. Mir
& Edwin M. Southern doi:10.1038/nbt0697-537 Abstract + references | PDF
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v Integrins as receptors for tumor targeting by circulating ligands pp542 - 546 Renata Pasqualini, Erkki Koivunen
& Erkki Ruoslahti doi:10.1038/nbt0697-542 Abstract + references | PDF
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Peptide mimicry of carbohydrate epitopes on human immunodeficiency virus pp547 - 551 Michael Agadjanyan, Ping Luo, M.A. Julie Westerink, Lisa A. Carey, Wendy Hutchins, Zenon Steplewski, David B. Weiner
& Thomas Kieber-Emmons doi:10.1038/nbt0697-547 Abstract + references | PDF
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Yeast surface display for screening combinatorial polypeptide libraries pp553 - 557 Eric T. Boder
& K. Dane Wittrup doi:10.1038/nbt0697-553 Abstract + references | PDF
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Use of a modified bacteriophage to probe the interactions between peptides and ion channel receptors in mammalian cells pp559 - 563 Min Li doi:10.1038/nbt0697-559 Abstract + references | PDF
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Generation of Rhizobium strains with improved symbiotic properties by random DNA amplification (RDA) pp564 - 569 Patrick Mavingui, Margarita Flores, David Romero, Esperanza Martinez-Romero
& Rafael Palacios doi:10.1038/nbt0697-564 Abstract + references | PDF
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Augmentation of blood platelet levels by intratracheal administration of an adenovirus vector encoding human thrombopoietin cDNA pp570 - 573 Salvatore J. Cannizzo, Beat M. Frey, Shahin Raffi, Malcolm A.S. Moore, Dan Eaton, Motoyoshi Suzuki, Ravi Singh, Charles A. Mack
& Ronald G. Crystal doi:10.1038/nbt0697-570 Abstract + references | PDF
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Bipotent progenitor cell lines from the human CNS pp574 - 580 Dinah W.Y. San, Jasodhara Ray
& Fred H. Gage doi:10.1038/nbt0697-574 Abstract + references | PDF
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Manipulating the aggregation and oxidation of human SPARC in the cytoplasm of Escherichia coli pp581 - 585 Eleonor L. Schneider, Jeffrey G. Thomas, James A. Bassuk, E. Hélèns Sage
& François Baneyx doi:10.1038/nbt0697-581 Abstract + references | PDF
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| Resources | Top |
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| Patents |
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Patenting DNA: Just when you thought it was safe pp586 - 587 Kenneth G. Chahine doi:10.1038/nbt0697-586 Abstract + references | PDF
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Patent applications in the area of monoclonal antibodies p588 doi:10.1038/nbt0697-588 PDF
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| WWW Guide |
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Browsing small genomes on the WWW p590 John C. Robbins doi:10.1038/nbt0697-590 PDF
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| People |
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People p591 doi:10.1038/nbt0697-591 PDF
(202K)
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| New Products |
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New Products p592 doi:10.1038/nbt0697-592 PDF
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| Industry Trends |
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Chiral-based therapeutics pp594 - 595 Arts Persidis doi:10.1038/nbt0697-594 Abstract + references | PDF
(346K)
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