Volume 15 Issue 6, June 1997

Empirical antisense

Collective unconsciousness

Translating genomics information into therapeutics: A key role for oligonucleotides

• Ralph E. Christoffersen

Novartis' role in 21st century drug development

• Daniel Vasella

The EPA's war on bioremediation

• Henry Miller

Mycogen's Caulder steps down but not out

• Russ Hoyle

Cloning our way to "the next level"

• Stuart A. Newman

Agouron annexes Alanex

Research news

This Month in Nature Biotechnology

Cephalon adds to clinical disappointment in 1997

• Vicki Glaser

Amgen protects its billion dollar protein

• Ken Chahine

Gene activation and EPO

• Sylvia Davidson

Antibiotech week raises tension over transgenic food

• Barbara Nasto
• Josh Lehrer

Whitehead consortium to develop new genome tools

• Vicki Brower

EPA issues, USDA amends respective biotech rules

• Jeffrey L Fox

Industry-linked groups, geneticists, hoard data

Conflicts brewing as phage display gets complex

• Vicki Glaser

Blood products have future despite recent setbacks

• Vicki Brower

Many are probed, but few are chosen

• Francis C. Szoka Jr.

Addressing tumor blood vessels

• Judah Folkman

A quick fix using random DNA amplification

• Robert Haselkorn

Trick and treat: Toward peptide mimic vaccines

• Alexander R. Shikhman
• Madeleine W. Cunningham

Refolding with a piece of the ring

• Jonathan King

Rethinking the development of breast cancer

• Robert S. Schehr

Cancer researchers validate and pursue telomerase

• Debra Robertson

Antisense '97: A roundtable on the state of the industry

Metabolic engineering and human disease

• Martin L. Yarmush
• François Berthiaume

From housekeeper to microsurgeon: The diagnostic and therapeutic potential of ribonucleases

• Catherine H. Schein

Selecting effective antisense reagents on combinatorial oligonucleotide arrays

• Natalie Milner
• Kalim U. Mir
• Edwin M. Southern

αv Integrins as receptors for tumor targeting by circulating ligands

• Renata Pasqualini
• Erkki Koivunen
• Erkki Ruoslahti

Peptide mimicry of carbohydrate epitopes on human immunodeficiency virus

• Michael Agadjanyan
• Ping Luo
• Thomas Kieber-Emmons

Yeast surface display for screening combinatorial polypeptide libraries

• Eric T. Boder
• K. Dane Wittrup

Use of a modified bacteriophage to probe the interactions between peptides and ion channel receptors in mammalian cells

• Min Li

Generation of Rhizobium strains with improved symbiotic properties by random DNA amplification (RDA)

• Patrick Mavingui
• Margarita Flores
• Rafael Palacios

Augmentation of blood platelet levels by intratracheal administration of an adenovirus vector encoding human thrombopoietin cDNA

• Salvatore J. Cannizzo
• Beat M. Frey
• Ronald G. Crystal

Bipotent progenitor cell lines from the human CNS

• Dinah W.Y. San
• Jasodhara Ray
• Fred H. Gage

Manipulating the aggregation and oxidation of human SPARC in the cytoplasm of Escherichia coli

• Eleonor L. Schneider
• Jeffrey G. Thomas
• François Baneyx

Patenting DNA: Just when you thought it was safe

• Kenneth G. Chahine

Patent applications in the area of monoclonal antibodies

Browsing small genomes on the WWW

• John C. Robbins

People

New Products

Chiral-based therapeutics

• Arts Persidis