Feature


Nature Biotechnology 15, 525 - 528 (1997)
doi:10.1038/nbt0697-525

Metabolic engineering and human disease

Martin L. Yarmush1 & François Berthiaume1


The study of metabolic networks could provide a new window into organ and tissue function, with great impact on many areas of medicine.

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  1. 1Martin L. Yarmush is the Helen Andrus Benedict Professor of surgery and Bioengineering and François Berthiaume is Instructor in Surgery and Bioengineering at the Centre for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, and the Shriners Burns Institute, 55 Fruit Street, Bigelow 1401, Boston, MA 02114.


Metabolic engineering and human disease - Nature Biotechnology
 
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Feature
Nature Biotechnology  15, 525 - 528 (1997)
doi:10.1038/nbt0697-525

Metabolic engineering and human disease

Martin L. Yarmush1 & François Berthiaume1

1Martin L. Yarmush is the Helen Andrus Benedict Professor of surgery and Bioengineering and François Berthiaume is Instructor in Surgery and Bioengineering at the Centre for Engineering in Medicine, Massachusetts General Hospital, Harvard Medical School, and the Shriners Burns Institute, 55 Fruit Street, Bigelow 1401, Boston, MA 02114.

The study of metabolic networks could provide a new window into organ and tissue function, with great impact on many areas of medicine.

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  1. Cameron, D.C. et al. 1993. Appl. Biochem. Biotechnol. 38: 105−140. | PubMed  | ISI | ChemPort |
  2. Stephanopoulos, G. 1994. Curr. Opin. Biotechnol. 5: 196−200. | PubMed  | ChemPort |
  3. Lapidot, A. et al. 1994. J. Biol. Chem. 269: 27198−27208. | PubMed  | ISI | ChemPort |
  4. Beylot, M. et al. 1996. Reprod. Nutr. Dev. 36: 363−373. | PubMed  | ISI | ChemPort |
  5. Malloy, C.R. et al. 1990. Am. J. Physiol. 259: H987−H995. | PubMed  | ISI | ChemPort |
  6. Varma, A. et al. 1994. Bio/Technology 12: 994−998. | ISI | ChemPort |
  7. Zupke, C. et al. 1995. Appl. Microbiol. Biotechnol. 44: 27−36. | Article | PubMed  | ISI | ChemPort |
  8. Fell, D.A. et al. 1986. Biochem. J. 238: 781−786. | PubMed  | ISI | ChemPort |
  9. Fell, D.A. 1992. Biochem. J. 286: 313−330. | PubMed  | ISI | ChemPort |
  10. Liao, J.C. et al. 1993. Biotechnol. Prog. 9: 221−233. | ISI | ChemPort |
  11. Jessen, M.E. et al. 1993. J. Clin. Invest. 92: 831−839. | PubMed  | ISI | ChemPort |
  12. Yatt, T.M. et al. 1992. pp. 88−91, in A Textbook of Cardioplegia tor Difficult Clinical Problems. Engleman, R.M., Levitsky, S. (eds). Futura Publishing, Mt. Kisco, NY.
  13. Jeffrey, F.M.H. et al. 1996. Am. J. Physiol. 271: E788−E799. | PubMed  | ISI | ChemPort |
  14. Sherry, A.D. et al. 1992. Biochemistry 31: 4833−4837. | PubMed  | ISI | ChemPort |
  15. Sumegi, B. et al. 1994. Biochem. J. 297: 109−113. | PubMed  | ISI | ChemPort |
  16. Jeffrey, F.M. et al. 1995. Basic Res. Cardiol. 90: 388−396. | PubMed  | ISI | ChemPort |
  17. Jeffrey, F.M. et al. 1995. J. Cardiovasc. Pharmacol.25: 469−472. | PubMed  | ISI | ChemPort |
  18. Cole, R.L. et al. 1990. Circulation 81: 1260−1270. | PubMed  | ISI |
  19. Cohen, S.M. 1987. Biochemistry 26: 5637−572. | PubMed  | ISI | ChemPort |
  20. Cohen, S.M.1987. Biochemistry 26: 573−580. | PubMed  | ISI | ChemPort |
  21. Cohen, S.M. 1987. Biochemistry 26: 581−589. | PubMed  | ISI | ChemPort |
  22. Rigoulet, M. et al. 1987. Biochem. J. 245: 661−668. | PubMed  | ISI | ChemPort |
  23. Groen, A.K. et al. 1983. J. Biol. Chem. 258: 14346−14353. | PubMed  | ChemPort |
  24. Groen, A.K. et al. 1986. Biochem. J. 237: 379−389. | PubMed  | ISI | ChemPort |
  25. Tayek, J.A. et al. 1996. Am. J. Physiol. 270: E709−E717. | PubMed  | ISI | ChemPort |
  26. Yang, D. et al. 1996. Am. J. Physiol. 270E882−E889. | PubMed  | ISI | ChemPort |
  27. Mizock, B.A. 1995. Am. J. Med. 98: 75−84. | Article | PubMed  | ISI | ChemPort |
  28. Wolfe, R.R. et al. 1978. J. Trauma 18: 800−805. | PubMed  | ISI | ChemPort |
  29. Yamaguchi, Y. et al. 1997. Surgery 121: 295−303. | PubMed  | ISI | ChemPort |
  30. Dahn, M.S. et al. 1996. Shock 6: 52−56. | PubMed  | ISI | ChemPort |
  31. Zupke, C.A. et al. 1997. Anal. Biochem. In press.
  32. Brown, G.C. 1994. Biochem. J. 297: 115−122. | PubMed  | ISI | ChemPort |
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