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| Opinion | Top |
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| Editorials |
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Postgenomic drug discovery p1219 doi:10.1038/nbt1197-1219a PDF
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Vorsicht emptor! p1219 doi:10.1038/nbt1197-1219b PDF
(139K)
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| Commentary |
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Drug discovery in the postgenomic era pp1220 - 1221 George Scangos doi:10.1038/nbt1197-1220 References | PDF
(272K)
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The challenges of genome sequence annotation or "The devil is in the details" pp1222 - 1223 Temple F. Smith
& Xiaolin Zhang doi:10.1038/nbt1197-1222 References | PDF
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Profit margins and epistemology pp1224 - 1225 Richard C. Strohman doi:10.1038/nbt1197-1224 References | PDF
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General Electric goes to the mat in the PCB wars p1227 Russ Hoyle doi:10.1038/nbt1197-1227 PDF
(145K)
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| Correspondence |
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From syntax to semantics p1228 Alain Rappaport doi:10.1038/nbt1197-1228a References | PDF
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Debunking hCG p1228 M. Ram Sairam
& Tony Antakly doi:10.1038/nbt1197-1228b References | PDF
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| In Brief | Top |
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| Business and Regulatory News |
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Business & Regulatory News pp1229 - 1230 doi:10.1038/nbt1197-1229 PDF
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| Research News |
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Research news p1231 doi:10.1038/nbt1197-1231 PDF
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| This Month in Biotechnology |
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This Month in Nature Biotechnology p1232 doi:10.1038/nbt1197-1232 PDF
(229K)
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| Analysis | Top |
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| Business and Regulatory News |
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Farmers say Monsanto's engineered cotton drops bolls p1233 Jeffrey L. Fox doi:10.1038/nbt1197-1233a PDF
(176K)
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Carbohydrates down, but not out pp1233 - 1234 Adam Michael doi:10.1038/nbt1197-1233b PDF
(305K)
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Strugglers may drop through Nasdaq net pp1234 - 1235 Emma Dorey
& John Hodgson doi:10.1038/nbt1197-1234 PDF
(420K)
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US biotechnology patent bids take a plunge p1236 Douglas Steinberg doi:10.1038/nbt1197-1236a PDF
(141K)
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Gene therapy experts ponder readiness for enhancements pp1236 - 1237 Jeffrey L. Fox doi:10.1038/nbt1197-1236b PDF
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Thalidomide checks might have saved Redux pp1238 - 1239 Vicki Brower doi:10.1038/nbt1197-1238 PDF
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Xenotransplant firms get xenophobic p1239 Barbara Nasto doi:10.1038/nbt1197-1239 PDF
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Enbrel's phase III reinforces prospects in RA p1240 Vicki Brower doi:10.1038/nbt1197-1240 PDF
(204K)
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FDA reform moves through Congress p1241 Jeffrey L. Fox doi:10.1038/nbt1197-1241 PDF
(230K)
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New flu treatments only a sniff away p1242 Vicki Glaser doi:10.1038/nbt1197-1242 PDF
(147K)
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| Research News |
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On target with tumor blood vessel markers pp1243 - 1244 Bruce R. Zetter doi:10.1038/nbt1197-1243 References | PDF
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Hormone peptidomimetics: Seeing double pp1244 - 1245 Andrew Braisted doi:10.1038/nbt1197-1244 References | PDF
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Future of farm animals glimpsed in Lake Tahoe? p1246 Philip Bernstein doi:10.1038/nbt1197-1246 References | PDF
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Repelling plant pathogens with ribonuclease p1247 John Hammond doi:10.1038/nbt1197-1247 References | PDF
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Growth hormone technology develops new twist p1248 Terry D. Etherton doi:10.1038/nbt1197-1248 References | PDF
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| Features | Top |
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Getting the right drug into the right patient pp1249 - 1252 Andrew Marshall doi:10.1038/nbt1197-1249 Abstract + references | PDF
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Finding a new language for bioinformatics pp1253 - 1256 Clare Sansom doi:10.1038/nbt1197-1253 Abstract | PDF
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| Research Review | Top |
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The simplicity of complex MACs pp1257 - 1259 Jean-Michel H. Vos doi:10.1038/nbt1197-1257 Abstract + references | PDF
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| Research Articles | Top |
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Increased potency of an erythropoietin peptide mimetic through covalent dimerization pp1261 - 1265 Nicholas C. Wrighton, Palaniappan Balasubramanian, Francis P. Barbone, Arun K. Kashyap, Francis X. Farrell, Linda K. Jolliffe, Ronald W. Barrett
& William J. Dower doi:10.1038/nbt1197-1261 Abstract + references | PDF
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Structure−based design and characterization of exocyclic peptidomimetics that inhibit TNF binding to its receptor pp1266 - 1270 Wataru Takasaki, Yuri Kajino, Kiichi Kajino, Ramachandran Murali
& Mark I. Greene doi:10.1038/nbt1197-1266 Abstract + references | PDF
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Targeting by affinity−matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform pp1271 - 1275 Dario Neri, Barbara Carnemolla, Ahuva Nissim, Alessandra Leprini, Germano Querzè, Enrica Balza, Alessandro Pini, Lorenzo Tarli, Cornelia Halin, Paolo Neri, Luciano Zardi
& Greg Winter doi:10.1038/nbt1197-1271 Abstract + references | PDF
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Creating a bifunctional protein by insertion of -lactamase into the maltodextrin-binding protein pp1276 - 1279 Jean-Michel Betton, Jansen P. Jacob, Maurice Hofnung
& Jenny K. Broome-Smith doi:10.1038/nbt1197-1276 Abstract + references | PDF
(567K)
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A protein particle vaccine containing multiple malaria epitopes pp1280 - 1284 Sarah C. Gilbert, Magdalena Plebanski, Stephen J. Harris, Catherine E.M. Allsopp, Rebecca Thomas, Guy T. Layton
& Adrian V.S. Hill doi:10.1038/nbt1197-1280 Abstract + references | PDF
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Enhanced growth by ectopic expression of growth hormone releasing hormone using an injectable myogenic vector pp1285 - 1289 Ruxandra Draghia-Akli, Xuyang Li
& Robert J. Schwartz doi:10.1038/nbt1197-1285 Abstract + references | PDF
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Transgenic potato expressing a double-stranded RNA-specific ribonuclease is resistant to potato spindle tuber viroid pp1290 - 1294 Teruo Sano, Akihiro Nagayama, Toshiya Ogawa, Isao Ishida
& Yoshimi Okada doi:10.1038/nbt1197-1290 Abstract + references | PDF
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Transformation of wheat with high molecular weight subunit genes results in improved functional properties pp1295 - 1299 Francisco Barro, Leonie Rooke, Frank Békés, Peter Gras, Arthur S. Tatham, Roger Fido, Paul A. Lazzeri, Peter R. Shewry
& Pilar Barceló doi:10.1038/nbt1197-1295 Abstract + references | PDF
(722K)
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Recovery of homogeneous and functional 2-adrenergic receptors from extracellular baculovirus particles pp1300 - 1304 Thomas P. Loisel, Hervé Ansanay, Stéphane St-Onge, Bernard Gay, Pierre Boulanger, A. Donny Strosberg, Stefano Marullo
& Michel Bouvier doi:10.1038/nbt1197-1300 Abstract + references | PDF
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| Resources | Top |
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| Patents |
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Patent prosecution: Be careful what you say pp1305 - 1307 Eugene C. Rzucidlo doi:10.1038/nbt1197-1305 Abstract + references | PDF
(626K)
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Patent applications in the area of electrophoresis p1308 doi:10.1038/nbt1197-1308a PDF
(609K)
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Automated SPE p1308 doi:10.1038/nbt1197-1308b PDF
(607K)
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| WWW Guide |
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Dissecting complex carbohydrates with "virtual" tools p1309 Edward McSweegan doi:10.1038/nbt1197-1309 PDF
(549K)
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| Profile |
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Allen Roses : Rebel with a cause p1310 Vicki Brower doi:10.1038/nbt1197-1310 Abstract | PDF
(189K)
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| People |
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People p1311 doi:10.1038/nbt1197-1311 PDF
(318K)
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| New Products |
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New Products:
Process monitoring & validation p1312 doi:10.1038/nbt1197-1312 PDF
(266K)
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| Industry Trends |
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Catalytic antibodies pp1313 - 1315 Aris Persidis doi:10.1038/nbt1197-1313 Abstract + references | PDF
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