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Focus
 
Systems Biology
Contents Editorial News Commentary Feature
Historical Perspective Perspective Reviews Feedback
This issue focuses on the potential applications of systems biology to biotechnology. Although at this stage, most models of biological systems are rather rudimentary, the proliferation of high-throughput technologies for gathering data on a large scale is spurring efforts to describe and predict the functioning of entire systems applicable to drug discovery, industrial biotechnology and other sectors.
Editorial Top
End of the interlude? p1191
doi:10.1038/nbt1004-1191
Full text | PDF (52K)
News Top
Profile: Fritjof Capra p1201
Laura DeFrancesco
doi:10.1038/nbt1004-1201
Abstract | Full text | PDF (102K)
Opinion and Comment Top
Commentary
A partnership between biology and engineering pp1211 - 1214
Roger Brent
doi:10.1038/nbt1004-1211
Full text | PDF (104K)
The impact of systems approaches on biological problems in drug discovery pp1215 - 1217
Leroy Hood & Roger M Perlmutter
doi:10.1038/nbt1004-1215
Full text | PDF (182K)
Two-dimensional annotation of genomes pp1218 - 1219
Bernhard Palsson
doi:10.1038/nbt1004-1218
Full text | PDF (111K)
Feature Top
Can complexity be commercialized? pp1223 - 1229
George S Mack
doi:10.1038/nbt1004-1223
Abstract | Full text | PDF (620K)
Historical Perspective Top
The evolution of molecular biology into systems biology pp1249 - 1252
Hans V Westerhoff & Bernhard O Palsson
Published online: 06 October 2004 | doi:10.1038/nbt1020
Abstract | Full text | PDF (110K)
Research Top
Perspective
Systems biology in drug discovery pp1253 - 1259
Eugene C Butcher, Ellen L Berg & Eric J Kunkel
Published online: 06 October 2004 | doi:10.1038/nbt1017
Abstract | Full text | PDF (438K)
Reviews
Exploiting biological complexity for strain improvement through systems biology pp1261 - 1267
Gregory Stephanopoulos, Hal Alper & Joel Moxley
Published online: 06 October 2004 | doi:10.1038/nbt1016
Abstract | Full text | PDF (511K)
The challenges of modeling mammalian biocomplexity pp1268 - 1274
Jeremy K Nicholson, Elaine Holmes, John C Lindon & Ian D Wilson
Published online: 06 October 2004 | doi:10.1038/nbt1015
Abstract | Full text | PDF (464K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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