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Focus
 
Focus on Diagnostics
  Contents     Editorials    News  Commentary
Features Research Review Feedback
Clinical diagnostics is a downstream application of a significant fraction of technologies published in Nature Biotechnology. This focus provides an overview of recent progress in biomarker discovery and validation and an assessment of the scientific, business, regulatory, intellectual property, technology transfer and logistical challenges in accelerating the integration of these markers into diagnostic tests for use in guiding treatment selection and dosage.
Editorials Top
Focus on Diagnostics
Lost in validation p869
doi:10.1038/nbt0806-869
Abstract | Full text | PDF (82K)
Focus on Diagnostics
Not for the chicken-hearted p870
doi:10.1038/nbt0806-870
Abstract | Full text | PDF (60K)
News Top
Data Page
Focus on Diagnostics
Diagnostics investors think positive p884
Stacy Lawrence
doi:10.1038/nbt0806-884
Full text | PDF (136K)
News Feature
Focus on Diagnostics
Looking for solid ground along the Critical Path pp885 - 887
Mark Ratner
Published online: 03 August 2006 | doi:10.1038/nbt0806-885
Abstract | Full text | PDF (470K)
Focus on Diagnostics
Genetic profiteering pp888 - 890
Laura De Francesco
Published online: 03 August 2006 | doi:10.1038/nbt0806-888
Abstract | Full text | PDF (964K)  | Supplementary Information
Focus on Diagnostics
Moving diagnostics from the bench to the bedside pp891 - 893
Jim Kling
Published online: 03 August 2006 | doi:10.1038/nbt0806-891
Abstract | Full text | PDF (374K)
Opinion and Comment Top
Commentary
Focus on Diagnostics
Cancer biomarkers: a systems approach pp905 - 908
Lee Hartwell, David Mankoff, Amanda Paulovich, Scott Ramsey & Elizabeth Swisher
doi:10.1038/nbt0806-905
Abstract | Full text | PDF (141K)
Focus on Diagnostics
Translating in vivo diagnostics into clinical reality pp909 - 913
John V Frangioni
doi:10.1038/nbt0806-909
Abstract | Full text | PDF (1,488K)
Focus on Diagnostics
What brown cannot do for you pp914 - 916
David L Rimm
doi:10.1038/nbt0806-914
Abstract | Full text | PDF (444K)
Focus on Diagnostics
Three barriers to innovative diagnostics pp917 - 918
Paul R Billings
doi:10.1038/nbt0806-917
Abstract | Full text | PDF (923K)
Focus on Diagnostics
Partnering for better microbial diagnostics pp919 - 921
Mark D Perkins & Peter M Small
doi:10.1038/nbt0806-919
Abstract | Full text | PDF (295K)
Focus on Diagnostics
A change in the market—investing in diagnostics pp922 - 926
Keith Batchelder & Peter Miller
doi:10.1038/nbt0806-922
Abstract | Full text | PDF (342K)
Focus on Diagnostics
A regulatory perspective on in vitro diagnostics pp927 - 929
Scott Gottlieb & Janet Woodcock
doi:10.1038/nbt0806-927
Abstract | Full text | PDF (678K)
Investor's Lab
Focus on Diagnostics
Any diamonds in the diagnostic coal? p930
Tom Jacobs
doi:10.1038/nbt0806-930
Full text | PDF (69K)
Features Top
Focus on Diagnostics
New-wave diagnostics pp931 - 938
Monya Baker
doi:10.1038/nbt0806-931
Abstract | Full text | PDF (2,215K)
Patents
Focus on Diagnostics
Emerging patent issues in genomic diagnostics pp939 - 941
John H Barton
doi:10.1038/nbt0806-939
Abstract | Full text | PDF (596K)
Focus on Diagnostics
Shifting emphasis from pharmacogenomics to theragnostics pp942 - 946
Vural Ozdemir, Bryn Williams-Jones, Stephen J Glatt, Ming T Tsuang, James B Lohr & Christopher Reist
doi:10.1038/nbt0806-942
Abstract | Full text | PDF (133K)
Focus on Diagnostics
Recent patent applications in molecular diagnostics p947
doi:10.1038/nbt0806-947
Full text | PDF (41K)
Research Top
Perspective
Focus on Diagnostics
Protein biomarker discovery and validation: the long and uncertain path to clinical utility pp971 - 983
Nader Rifai, Michael A Gillette & Steven A Carr
Published online: 09 August 2006 | doi:10.1038/nbt1235
Abstract | Full text | PDF (384K)
Review
Focus on Diagnostics
The role of companion diagnostics in the development and use of mutation-targeted cancer therapies pp985 - 995
Nickolas Papadopoulos, Kenneth W Kinzler & Bert Vogelstein
Published online: 09 August 2006 | doi:10.1038/nbt1234
Abstract | Full text | PDF (1,341K)
  Top
 
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Nature Biotechnology
ISSN: 1087-0156
EISSN: 1546-1696
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