Editorials

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  • The scientific integrity of US government agencies is under attack from the Trump administration. Agency senior executives and industry leaders need to continue pushing back.

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  • The pandemic has highlighted long-standing, deep-rooted challenges to the sharing of biological samples. Greater attention is needed to mechanisms for incentivizing materials transfer.

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  • As preliminary research findings are shared more widely and at an increasing pace, action is needed to counter the spread of misinformation.

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  • As CRISPR–Cas9 enters human testing, the blistering pace of progress in preclinical research is offering a bewildering array of options for therapeutic gene editing.

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  • A slew of national COVID-19 exposure apps have failed because of poor public engagement and acceptance. Apps from the workplace may offer a partial solution if privacy can be guaranteed.

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  • Insufficient SARS-CoV-2 testing has left many nations flying blind as they reopen their economies. Without adequate testing, new infections could outrun control measures.

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  • COVID-19 has reinforced the importance of preprints as an indispensable means for rapid research dissemination.

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  • In the onslaught of the COVID-19 pandemic, the open sharing of materials, information and data is gaining increasing importance in biotech.

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  • In the post-Brexit era, Britain must rapidly harmonize national and European law, secure unfettered access to global talent and address funding shortfalls to ensure continued leadership in the life sciences.

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  • The US Food and Drug Administration is sticking to its plan to carry out mandatory premarket review of all gene-edited livestock, irrespective of trait risk. It should rethink.

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  • Was the public re-release of data excerpts from an unpublished manuscript on human germline gene editing ethically justified?

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  • 150 years after its founding, Nature has not only published some of biotech’s seminal papers, but also profoundly influenced the sector’s impact on society.

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  • China is set to challenge the pre-eminence of the US drug market. If it can address gaps in its R&D ecosystem and clinical infrastructure, it may even become a home for biotech innovators.

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  • To capitalize on progress in neuromodulation, funders and clinicians should promote not only translational research, but also data sharing.

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  • Heavy-handed targeting of ethnic Chinese researchers, students and investors by US funding, intelligence and immigration agencies poses a threat to the American life-sciences sector.

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  • Sky-high-priced gene therapies face slow uptake and market failure unless healthcare payers and drug makers can find common ground in ‘pay-for-performance’ reimbursement.

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  • Nature Biotechnology’s peer review trial with Code Ocean highlights the importance of ‘containers’ in enhancing software usability, reproducibility and code-writing in academia.

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  • The outgoing FDA commissioner’s comments on the slow integration of data from mobile platforms into clinical research highlight the challenges facing real-world applications of wearables.

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