<?xml version="1.0" encoding="UTF-8"?>
<job>
  <id type="integer">119498</id>
  <reference-id>188053</reference-id>
  <requisition-number></requisition-number>
  <source>Naturejobs.com - Ecommerce</source>
  <company-url>http://www.chem.unc.edu/people/faculty/desimone/</company-url>
  <employer-url>http://www.chem.unc.edu/people/faculty/desimone/</employer-url>
  <application-email>mnapier@email.unc.edu</application-email>
  <application-url></application-url>
  <employer-name>University of North Carolina at Chapel Hill, Department of Chemistry</employer-name>
  <company-name>University of North Carolina at Chapel Hill, Department of Chemistry</company-name>
  <description>
    <![CDATA[Multiple postdoctoral positions are available in the academic laboratory of Joseph DeSimone at the University of North Carolina at Chapel Hill, http://www.chem.unc.edu/people/faculty/desimone/.  The research in the DeSimone laboratories is focused on using Particle Replication in Non-wetting Templates (PRINT) technology to develop precisely engineered micro- and nanoparticles for the delivery of biological and small molecule therapeutics.  PRINT is an extremely versatile and flexible method for the direct fabrication and harvesting of monodisperse, shape-specific nano-biomaterials.  PRINT particles are presently being designed to reach new understandings and therapies in cancer prevention, diagnosis, and treatment.

We are looking for creative, talented, and motivated individuals to work with us.  This position offers challenge, individual growth opportunities, and continuous variety for a highly motivated individual.  In this role, you will work in a hands-on, dynamic academic laboratory environment engaged in the research and continued development of micro- and nano-particles for delivery of a variety of cargos, including siRNA, chemotherapeutics, proteins, and peptides.  You will design and execute experiments to evaluate particle-based delivery of the particles _in vitro_ and _in vivo_.  Cell culture work may include gene silencing, cell viability, flow cytometry, and confocal microscopy assays to understand the fundamentals of intracellular internalization and trafficking.  _In vivo_ work will likely consist of gene silencing, PK/biodistribution, tumor regression, and imaging experiments using a variety of animal models.

Applicants must possess a PhD in Chemistry, Bioengineering, Biochemistry, Molecular Biology, or other physical sciences related field.  Demonstrated laboratory experimentation skills across a broad spectrum of responsibilities including characterization of particles by AFM, SEM, FTIR, DLS, Zeta Potential, and other techniques is required.  Experience with polymer-based nanoparticle systems for the delivery of therapeutics _in vivo_ is preferred. Candidates must be creative and detail-oriented with strong analytical and communication skills, as well as an ability to thrive in a multidisciplinary team environment.

Please send your CV and the names and contact information for three references to Mary Napier, mnapier@email.unc.edu and Vicki Haithcock, vph@email.unc.edu.]]>
  </description>
  <location>Chapel Hill, NC, 27599</location>
  <title>Postdoctoral Associate, Nanotechnology &amp; Drug Delivery</title>
  <created-on type="datetime">Wed, 04 Nov 2009 12:08:29 -0500</created-on>
  <expires-on type="datetime">Sun, 03 Jan 2010 00:00:00 -0500</expires-on>
  <url>http://www.nature.com/naturejobs/science/jobs/119498-Postdoctoral-Associate-Nanotechnology-Drug-Delivery</url>
  <packages>
    <package>Spotlight</package>
  </packages>
</job>
