<?xml version="1.0" encoding="UTF-8"?>
<job>
  <id type="integer">114230</id>
  <reference-id>185911a</reference-id>
  <requisition-number></requisition-number>
  <source>Naturejobs.com - Ecommerce</source>
  <company-url>http://www.syngeneintl.com/</company-url>
  <employer-url>http://www.syngeneintl.com/</employer-url>
  <application-email>satya.kumar@syngeneintl.com</application-email>
  <application-url></application-url>
  <employer-name>Syngene International</employer-name>
  <company-name>Syngene International</company-name>
  <description>
    <![CDATA[
Syngene is an internationally reputed contract research and manufacturing organisation with multidisciplinary skills in chemistry and biology services. From early stage discovery and process development through to cGMP manufacturing, we provide customised services to pharmaceutical and biotechnology majors, on a strong platform of confidentiality and intellectual property protection.

*Position: Sr. Scientific Manager/ Chief Scientific Manager- Discovery Metabolism and Pharmacokinetics (MAP)*

*Qualification:* PhD/ PDF in pharmaceutical sciences (e.g. pharmacokinetics, drug metabolism) or any related discipline.

*Experience:* Minimum of 7 years of professional (industry) experience.

*Role:*
• The major responsibility of the selected candidate will be to lead the Metabolism and Pharmacokinetics group, focused on non clinical pharmacokinetic and metabolism of new chemical entities, in support of various drug discovery programs.
• He/she will represent the department at all discovery working group meetings, suggest and implement strategies and tactics to address PK/PD/ADME related issues and ultimately enable program decision-making in the selection and advancement of high-quality drug candidates from discovery into development.
• The incumbent will collaborate with a broad group of scientists in the various PCO department, as well as scientists across various disciplines in the Discovery organization. The individual will play a major role in setting group strategy, vision, and take a lead in key scientific initiatives.

*Skill set:* Hands-on experience and in-depth training in the areas of non clinical pharmacokinetics (PK), pharmacodynamics (PD) and/or drug metabolism are required. These include, but not limited to, PK and PK/PD study design and data analysis, drug metabolism concepts and assays, enzyme kinetics, etc. Hands-on experience in conducting in vitro and in vivo studies to assess the ADME of discovery compounds (cell culture, metabolic stability models, CYP inhibition etc.) required. Demonstrated experience supporting lead optimization programs, and preclinical candidate characterization to enable studies towards regulatory submissions like IND is necessary.

Strong problem solving and leadership skills are required. In addition, excellent interpersonal and communication skills (written and spoken) are mandatory in order to perform in a matrix team environment. The incumbent should be a strong scientist and be able to manage a group of Ph.D., M.S. and B.S. staff.

*Location:* Bangalore
]]>
  </description>
  <location>Bangalore, Karnataka 560099 India</location>
  <title>Sr. Scientific Manager / Chief Scientific Manager- Discovery Metabolism and Pharmacokinetics (MAP)</title>
  <created-on type="datetime">Thu, 01 Oct 2009 04:00:00 -0400</created-on>
  <expires-on type="datetime">Thu, 26 Nov 2009 05:00:00 -0500</expires-on>
  <url>http://www.nature.com/naturejobs/science/jobs/114230-Sr-Scientific-Manager-Chief-Scientific-Manager-Discovery-Metabolism-and-Pharmacokinetics-MAP</url>
  <packages>
    <package>Job Match</package>
  </packages>
</job>
