<?xml version="1.0" encoding="UTF-8"?>
<job>
  <id type="integer">108961</id>
  <reference-id>184942</reference-id>
  <requisition-number></requisition-number>
  <source>Naturejobs.com - Ecommerce</source>
  <company-url>http://ki.se</company-url>
  <employer-url>http://ki.se</employer-url>
  <application-email>pezaph@ki.se</application-email>
  <application-url></application-url>
  <employer-name>Karolinska Institutet</employer-name>
  <company-name>Karolinska Institutet</company-name>
  <description>
    <![CDATA[*Motivated and enthusiastic* fellows are invited to apply for a postdoctoral position addressing the role of *RNA-based mechanisms* in the control of the *Hedgehog signaling* pathway.

In recent years there has been overwhelming evidence highlighting the significance of novel classes of RNA molecules in biological processes, including *micro RNAs*, *antisense transcripts* and *splice variants*. Moreover, the Hedgehog signal transduction cascade is   implicated not only in developmental processes but its dysregulation has been associated with an increasing spectrum of human tumors, including *medulloblastoma* and *pancreatic cancer*. Our goals center at dissecting key molecular events, relevant to Hedgehog signaling-mediated tumorigenesis, which are mediated through novel RNA-based mechanisms.

Recent publications:
*Oncogene* 26, 4889-4896, 2007 (_www.nature.com/onc/journal/v26/n34/abs/1210301a.html_) 
*J. Biol.Chem.* 283, 14345-14354, 2008 (_www.jbc.org/cgi/content/abstract/283/21/14345_)

Expertise in molecular biology techniques is required. Additionally, the capacity of independent reasoning combined with the willingness to work within a group is essential. The position is for one year but with the possibility of extension. 

Please send CV and letters of recommendations to either Peter Zaphiropoulos (pezaph@ki.se) or Takashi Shimokawa (takshi@ki.se) at the Department of Biosciences and Nutrition, Karolinska Institutet, 141 57 Huddinge, Sweden.  ]]>
  </description>
  <location>Huddinge, Stockholm, Sweden</location>
  <title>Postdoctoral Fellow in Cancer Molecular Biology </title>
  <created-on type="datetime">Mon, 31 Aug 2009 04:01:52 -0400</created-on>
  <expires-on type="datetime">Tue, 15 Dec 2009 00:00:00 -0500</expires-on>
  <url>http://www.nature.com/naturejobs/science/jobs/108961-Postdoctoral-Fellow-in-Cancer-Molecular-Biology</url>
  <packages>
  </packages>
</job>
