Article source: Nature

Nature 445, 948 (February 2007) | doi:10.1038/nj7130-948b

Torn between two ladders

Alexander Griekspoor1

  1. Alexander Griekspoor is a Marie Curie postdoctoral fellow at the EMBL European Bioinformatics Institute.

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Jumping to a new discipline brings both anxiety and satisfaction.

Much has been said about the pyramidal structure in academic science. But what if budding scientists discover halfway into their PhD that they're climbing the wrong career ladder? I was fortunate enough to find a way to change the focus of my career without having to compromise.

I believe that established scientists generally share a passion for science. Like Archimedes making his most famous discovery while bathing, their research questions stay with them even outside the lab. Near the end of my master's studies I worked in the cell-biology lab of one such scientist. His endless enthusiasm fostered a great lab environment. I accepted an offer to stay for my PhD. I don't regret this decision; my PhD was exciting and successful. But towards the end I struggled with what to do next.

Up to that point, I hadn't had moments of crisis like many PhD students who fear they'll never publish. From the start we formed exciting, successful collaborations. Still, I did not have the passion for cell biology that I saw in my supervisor on a daily basis. Then I started to develop an interest in programming. Along with a friend and fellow PhD student, I developed several scientific applications to help molecular biologists analyse and construct DNA sequences. It became my passion. Outside the lab, I stopped thinking about cell biology and started thinking about my programs.

What to do next? I considered a hybrid subject, such as electron microscopy, but had difficulty devising a grant proposal. My rescue came in the form of the annual postdoc retreat organized by the Netherlands Cancer Institute. A break from the lab bench and stimulating lectures helped me think about my options. A talk about community-based software that might lead to a more open discussion and valuation of scientific articles sparked lots of research ideas.

Two months ago, I started at the text mining group at the European BioInformatics Institute in Hinxton near Cambridge, UK. I already feel right at home in this completely different field. I now realize that pursuing some 'hybrid' postdoc would have been a mistake. My creativity and passion lie with computers and bioinformatics. If I'd compromised rather than making the leap to a new field, I would have been unhappy and less enthusiastic. When I discovered I was climbing the wrong ladder I had to make the jump to one that suited me more.

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