Meeting programRoche - Nature Medicine Translational Neuroscience Symposium 2009: Autism and Other Developmental Brain Disorders

Scientific Sessions

  • Session I. Synapse: Molecular Architecture and Function
  • Session II. Tuberous Sclerosis
  • Session III. Fragile X
  • Session IV. Rett Syndrome
  • Session V. Autism
  • Session VI. Plenary Lecture and Roche Awards Ceremony
Thursday, April 16  
18:30 - 21:30

Welcome Hospitality & Registration
Roche Forum Buonas
Friday, April 17  
8:30 - 8:45

Welcome
Luca Santarelli
Roche CNS Disease Biology Leadership Team

Juan Carlos Lopez
Chief Editor, Nature Medicine

8:45 - 9:15

Introduction
Autism: What we know? What we need?
Thomas Insel
Director, National Institute of Mental Health
National Institutes of Health

Session I

Synapse: Molecular Architecture & Function
Chaired by Morgan Sheng

9:15 - 10:00

Synaptic proteins, synapse maturation and autism spectrum disorders
Morgan Sheng
Genentech

10:00 - 10:30

Coffee

10:30 - 11:15

Synaptic function
Roberto Malinow
University of California, San Diego

11:15 - 12:00

Neurexins and neuroligins: From synapses to autism
Thomas Sudhof
Stanford University

12:00 - 13:00

Lunch

Session II

Tuberous Sclerosis
Chaired by Alcino Silva
13:00 - 13:45

Molecular and cellular mechanisms underlying the learning disabilities associated with disruptions of Ras/MAPK signaling: from the lab to the clinic
Alcino Silva
University of California, Los Angeles

13:45 - 14:30

Can we reverse the physical and neurodevelopmental deficits of Tuberous Sclerosis?
Petrus De Vries
University of Cambridge

14:30 - 15:00

Coffee

Session III

Fragile X
Chaired by Randi Hagerman
15:00 - 15:45

The pathophysiology of Fragile X syndrome
Stephen Warren
Department of Human Genetics, Emory University

15:45 - 16:30

Fragile X: Translation in action
Mark Bear
The Picower Center for Learning and Memory, MIT

16:30 - 17:15

Involvement in permutation carriers both young and old
Randi Hagerman
M.I.N.D Institute, UC Davis

17:15 - 17:30

Introduction to poster session
17:30 - 18:45

Poster presentations and cocktails
18:45

Dinner at Buonas

21:00 - 22:00

Bus transfers available to hotels in Lucerne (22:00 latest departure)

DAY ONE ENDS  
 
Saturday, April 18  
Session IV

Rett Syndrome
Chaired by Jeffery L. Neul
8:30 - 9:15

Genetics of Rett and Rett-like syndromes
Jamel Chelly
Institut Cochin

9:15 - 10:00

Rett syndrome and MECP2-related disorders: pathological insights from the clinic and the laboratory
Jeffery L. Neul
Baylor College of Medicine

10:00 - 10:30

Coffee

Session V

Autism
Chaired by Chris Walsh
10:30 - 11:15

New approaches to early detection and intervention in autism
Geraldine Dawson
Autism Speaks and Former Director, University of Washington Autism Center

11:15 - 12:00

Clinical presentation of autism
Anthony Bailey
University of Oxford & Autism Research

12:00 - 13:00

Lunch

13:00 - 13:45

Abnormal synaptic homeostasis in autism spectrum disorders
Thomas Bourgeron
Institute Pasteur, Paris

13:45 - 14:30

Worldwide, and genome-wide, searches for autism genes
Chris Walsh
Children's Hospital Boston, Harvard University

14:30 - 15:15

Assessing rare structural and sequence variations in autism spectrum disorders
Matthew State
Yale School of Medicine

15:15 - 15:45

Coffee

Session VI

Plenary Lecture & Prize Ceremony
15:45 - 16:30

Key learnings & future directions
Thomas Insel
National Institute of Mental Health, National Institutes of Health

16:30 - 17:30

Prize ceremony and closing remarks
Juan Carlos Lopez, Luca Santarelli and Christer Nordstedt

17:30 - 18:00

Bus transfers available to the Grand Hotel Europe in Lucerne, Lucerne Main Station and Roche Basel

PROGRAM ENDS