Meeting program - Nature Chemical Biology Symposium 2009: Chemical Biology in Drug Discovery
Meeting Program
| Saturday, September 19 | ||
|---|---|---|
| Introduction | ||
| 7:00 a.m. | Registration | |
| 8:30 a.m. | Joanne Kotz Nature Chemical Biology, USA |
|
| 8:40 a.m. | What does chemical biology have to offer and what does drug development need? Paul Workman Cancer Research UK Centre for Cancer Therapeutics at The Institute of Cancer Research, UK |
|
| Session 1 - Cell-based screening and target deconvolution | ||
| 9:10 a.m. | Introduction Chair: Gerard Drewes Cellzome, Germany |
|
| 9:20 a.m. | The gap between scientists' aspirations and society's expectations Stuart Schreiber Broad Institute, USA |
|
| 10:00 a.m. | A combined chemical genetic/RNAi approach: New tools to study cell division Ulrike Eggert Dana Farber Cancer Institute, USA |
|
| 10:40 a.m. | Coffee Break | |
| 11:10 a.m. | Knowledge-based triaging of chemical biology screens Jeremy Jenkins Novartis, USA |
|
| 11:50 a.m. | Chemical genomic tools to understand drug action and gene function Guri Giaever University of Toronto, Canada |
|
| 12:30 p.m. | Lunch | |
| Session 2 - Targeting pathways and systems | ||
| 1:30 p.m. | Introduction Chair: Carolyn Cho Pfizer, USA |
|
| 1:40 p.m. | Chemical proteomics and the mechanism of action of kinase inhibitors Giulio Superti-Furga Center for Molecular Medicine, Austrian Academy of Sciences, Austria |
|
| 2:20 p.m. | Systems biology from drug combinations Joseph Lehar CombinatoRx, USA |
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| 3:00 p.m. | The chemical biology of behavior and psychiatric disease Randall Peterson Massachusetts General Hospital, USA |
|
| 3:40 p.m. | Coffee Break | |
| 4:10 p.m. | A systems biology approach to the discovery of novel pathways Cristiano Migliorini Roche, Switzerland |
|
| 4:50 p.m. | Genomic information in drug discovery Todd Golub Broad Institute, USA |
|
| 5:30 p.m. | Reception and Poster Session | |
| Sunday, September 20 | ||
| Session 3 - Expanding druggable chemical space | ||
| 8:30 a.m. | Introduction Chair: Michael Hann GlaxoSmithKline, UK |
|
| 8:40 a.m. | Exploration of chemical space for drug discovery by database generation Jean-Louis Reymond University of Berne, Switzerland |
|
| 9:20 a.m. | Thinking the undruggable: Peptides, peptidomimetics, and natural products Peter Wipf University of Pittsburgh, USA |
|
| 10:00 a.m. | Alkaloid biosynthesis in periwinkle Sarah O'Connor Massachusetts Institute of Technology, USA |
|
| 10:40 a.m. | Coffee Break | |
| 11:10 a.m. | Natural product-based libraries for chemical biology and drug discovery Derek Tan Memorial Sloan Kettering Cancer Center, USA |
|
| 11:50 a.m. | Figments, fragments, and the gobsmacking emptiness of chemical space Brian Shoichet University of California, San Francisco, USA |
|
| 12:30 p.m. | Lunch | |
| Session 4 - Expanding druggable targets | ||
| 1:30 p.m. | Introduction Chair: Stephen Fesik Vanderbilt University, USA |
|
| 1:40 p.m. | Chemical genetic dissection of protein and lipid kinase regulatory networks Kevan Shokat University of California, San Francisco, USA |
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| 2:20 p.m. | Oxygenase mediated epigenetic modifications - emerging targets for drug discovery Christopher Schofield University of Oxford, UK |
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| 3:00 p.m. | Targeting cancer pathways with small molecule kinase inhibitors Nathanael Gray Dana Farber Cancer Institute, USA |
|
| 3:40 p.m. | Coffee Break | |
| 4:10 p.m. | Drug discovery harnessing RNA interference Muthiah Manoharan Alnylam, USA |
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| 4:50 p.m. | Drugging the "undruggable" Gregory Verdine Harvard University, USA |
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| 5:30 p.m. | Closing remarks Terry Sheppard Nature Chemical Biology, USA |
|
All presentations will be in English.
