Meeting program
Translational Approaches to Cardiovascular Research
Sunday, October 14
- 11:00-16:00 Registration
- 16:45-17:00 Opening remarks
- Session 1. Genetics and Genomics I
- 17:00-17:40 "Size matters: need for large-scale population studies"
- Rory Collins (University of Oxford; Biobank, UK)
- 17:40-18:20 "Role of genetic markers in myocardial infarction"
- Pier Mannucci (University of Milan, Italy)
- 18:20-19:00 "Genome-wide scan in a Sardinian cohort reveals candidate genes associated with quantitative cardiovascular-related traits"
- David Schlessinger (National Institute on Aging; National Institutes of Health, USA)
- 19:30 Welcome cocktail and poster session
Monday, October 15
- Session 2. Genetics and Genomics II
- 8:30-9:10 "An investment in the future of cardiovascular medicine"
- Elizabeth G. Nabel (National Heart, Lung, and Blood Institute; National Institutes of Health, USA)
- 9:10-9:50 "Transforming the practice of cardiovascular medicine using genomics"
- Geoffrey Ginsburg (Duke University, USA)
- 9:50-10:30 "Molecular dissection of cardiac repolarization and sudden cardiac death"
- Aravinda Chakravarti (Johns Hopkins School of Medicine, USA)
- 10:30-11:00 Coffee break
- Session 3. New Tools I (Metabolomics and Proteomics)
- 11:00-11:40 "Proteomic biomarkers in coronary artery disease"
- Anna Dominiczak (University of Glasgow, UK)
- 11:40-12:20 "Towards a metabolomics platform for cardiovascular disease: insights from planned heart attacks"
- Robert Gerszten (Massachusetts General Hospital; Broad Institute, USA)
- 12:20-13:00 "Applications of metabolomics to diabetes, obesity and cardiovascular disease"
- Julian L. Griffin (University of Cambridge, UK)
- 13:00-15:00 Lunch and poster session
- Session 4. New Tools II (Imaging)
- 15:00-15:40 "Multimodality (pet/ct, mr and ct) imaging of the atherosclerotic plaque and novel nanoparticulate drug delivery: implications for cardiovascular drug design and discovery"
- Zahi Fayad (Mount Sinai School of Medicine, USA)
- 15:40-16:20 Peter Libby (Brigham and Women's Hospital, USA)
- 16:20-17:00 "Tracking regression and progression of atherosclerosis with intravascular ultrasound"
- Stephen J. Nicholls (Cleveland Clinic, USA)
- 17:00-17:30 Coffee break
- Session 5. Advances in Cardiovascular Biology I
- 17:30-18:10 "MicroRNA regulation of cardiovascular biology and disease"
- Deepak Srivastava (University of California - San Francisco, USA)
- 18:10-18:50 Joseph Metzger (University of Michigan - Ann Arbor, USA)
- 18:50-19:30 "Postpartum cardiomyopathy: from mice to women"
- Helmut Drexler (Hannover Medical School, Germany)
- 19:30-19:45 "cAMP-dependent neointimal cushion formation in rat ductus arteriosus"
- Susumu Minamisawa (Waseda University, Japan)
- 19:45-20:00 "Akt is a determinant for L-type calcium channel protein stability and cardiac contraction"
- Daniele Catalucci (Fondazione Parco Biomedico San Raffaele, Italy)
Tuesday, October 16
- Session 6. Advances in Cardiovascular Biology II
- 8:30-9:10 "Signaling cardiac hypertrophy - novel tools and mechanisms"
- Stefan Engelhardt (University of Wuerzburg, Germany)
- 9:10-9:50 "HDAC2 and cardiac hypertrophy"
- Jonathan Epstein (University of Pennsylvania, USA)
- 9:50-10:30 "Adipokines, myokines and cardiovascular disease"
- Ken Walsh (Boston University, USA)
- 10:30-11:00 Coffee break
- Session 7. New Therapeutic Strategies I
- 11:00-11:40 "The nitrite-nitric oxide pathway in physiology and therapeutics"
- Mark Gladwin (National Heart, Lung, and Blood Institute; National Institutes of Health, USA)
- 11:40-12:20 "Oxidative enzymopathies in cardiovascular disease"
- Joseph Loscalzo (Brigham and Women's Hospital; Harvard Medical School, USA)
- 12:20-12:35 "Identifying genes which control collateral vessel development in zebrafish embryos"
- Tim Chico (University of Sheffield UK)
- 12:35-12:50 "Trpv4 and Abra: novel factors determine the growth of collateral vessels in response to arterial occlusions (arteriogenesis)"
- Kerstin Troidl (Max-Planck-Institute for Heart and Lung Research, Germany)
- 12:50-15:00 Lunch and poster session
- Session 8. New Therapeutic Strategies II
- 15:00-15:40 "New developments in gene therapy for heart failure"
- Roger Hajjar (Mount Sinai School of Medicine, USA)
- 15:40-16:20 Tullio Pozzan (University of Padova, Italy)
- 16:20-17:00 "Autologous progenitor cell therapy for acute myocardial infarction"
- Andreas M. Zeiher (J.W. Goethe University, Germany)
- 17:00-17:30 Coffee break
- Session 9. Roadblocks to Translational Research in Cardiovascular Disease
- 17:30-19:30 Roundtable



