Meeting program

Translational Approaches to Cardiovascular Research

Sunday, October 14

  • 11:00-16:00   Registration
  • 16:45-17:00   Opening remarks
  • Session 1.    Genetics and Genomics I
  • 17:00-17:40   "Size matters: need for large-scale population studies"
  •                      Rory Collins (University of Oxford; Biobank, UK)
  • 17:40-18:20   "Role of genetic markers in myocardial infarction"
  •                      Pier Mannucci (University of Milan, Italy)
  • 18:20-19:00   "Genome-wide scan in a Sardinian cohort reveals candidate genes associated with quantitative cardiovascular-related traits"
  •                      David Schlessinger (National Institute on Aging; National Institutes of Health, USA)

  • 19:30            Welcome cocktail and poster session

Monday, October 15

  • Session 2.    Genetics and Genomics II

  • 8:30-9:10      "An investment in the future of cardiovascular medicine"
  •                      Elizabeth G. Nabel (National Heart, Lung, and Blood Institute; National Institutes of Health, USA)
  • 9:10-9:50      "Transforming the practice of cardiovascular medicine using genomics"
  •                      Geoffrey Ginsburg (Duke University, USA)
  • 9:50-10:30    "Molecular dissection of cardiac repolarization and sudden cardiac death"
  •                      Aravinda Chakravarti (Johns Hopkins School of Medicine, USA)

  • 10:30-11:00   Coffee break

  • Session 3.    New Tools I (Metabolomics and Proteomics)

  • 11:00-11:40   "Proteomic biomarkers in coronary artery disease"
  •                      Anna Dominiczak (University of Glasgow, UK)
  • 11:40-12:20    "Towards a metabolomics platform for cardiovascular disease: insights from planned heart attacks"
  •                      Robert Gerszten (Massachusetts General Hospital; Broad Institute, USA)
  • 12:20-13:00   "Applications of metabolomics to diabetes, obesity and cardiovascular disease"
  •                      Julian L. Griffin (University of Cambridge, UK)
  • 13:00-15:00   Lunch and poster session

  • Session 4.    New Tools II (Imaging)

  • 15:00-15:40   "Multimodality (pet/ct, mr and ct) imaging of the atherosclerotic plaque and novel nanoparticulate drug delivery: implications for cardiovascular drug design and discovery"
  •                      Zahi Fayad (Mount Sinai School of Medicine, USA)
  • 15:40-16:20   Peter Libby (Brigham and Women's Hospital, USA)
  • 16:20-17:00   "Tracking regression and progression of atherosclerosis with intravascular ultrasound"
  •                      Stephen J. Nicholls (Cleveland Clinic, USA)

  • 17:00-17:30   Coffee break

  • Session 5.    Advances in Cardiovascular Biology I

  • 17:30-18:10   "MicroRNA regulation of cardiovascular biology and disease"
  •                      Deepak Srivastava (University of California - San Francisco, USA)
  • 18:10-18:50   Joseph Metzger (University of Michigan - Ann Arbor, USA)
  • 18:50-19:30   "Postpartum cardiomyopathy: from mice to women"
  •                      Helmut Drexler (Hannover Medical School, Germany)
  • 19:30-19:45   "cAMP-dependent neointimal cushion formation in rat ductus arteriosus"
  •                      Susumu Minamisawa (Waseda University, Japan)
  • 19:45-20:00   "Akt is a determinant for L-type calcium channel protein stability and cardiac contraction"
  •                      Daniele Catalucci (Fondazione Parco Biomedico San Raffaele, Italy)

Tuesday, October 16

  • Session 6.    Advances in Cardiovascular Biology II

  • 8:30-9:10      "Signaling cardiac hypertrophy - novel tools and mechanisms"
  •                      Stefan Engelhardt (University of Wuerzburg, Germany)
  • 9:10-9:50      "HDAC2 and cardiac hypertrophy"
  •                      Jonathan Epstein (University of Pennsylvania, USA)
  • 9:50-10:30    "Adipokines, myokines and cardiovascular disease"
  •                      Ken Walsh (Boston University, USA)

  • 10:30-11:00   Coffee break

  • Session 7.    New Therapeutic Strategies I

  • 11:00-11:40   "The nitrite-nitric oxide pathway in physiology and therapeutics"
  •                      Mark Gladwin (National Heart, Lung, and Blood Institute; National Institutes of Health, USA)
  • 11:40-12:20   "Oxidative enzymopathies in cardiovascular disease"
  •                      Joseph Loscalzo (Brigham and Women's Hospital; Harvard Medical School, USA)
  • 12:20-12:35   "Identifying genes which control collateral vessel development in zebrafish embryos"
  •                      Tim Chico (University of Sheffield UK)
  • 12:35-12:50   "Trpv4 and Abra: novel factors determine the growth of collateral vessels in response to arterial occlusions (arteriogenesis)"
  •                      Kerstin Troidl (Max-Planck-Institute for Heart and Lung Research, Germany)

  • 12:50-15:00   Lunch and poster session

  • Session 8.    New Therapeutic Strategies II

  • 15:00-15:40   "New developments in gene therapy for heart failure"
  •                      Roger Hajjar (Mount Sinai School of Medicine, USA)
  • 15:40-16:20   Tullio Pozzan (University of Padova, Italy)
  • 16:20-17:00   "Autologous progenitor cell therapy for acute myocardial infarction"
  •                      Andreas M. Zeiher (J.W. Goethe University, Germany)

  • 17:00-17:30   Coffee break

  • Session 9.    Roadblocks to Translational Research in Cardiovascular Disease

  • 17:30-19:30   Roundtable

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