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We are grateful for the support of our Sponsor The National Institutes of Health. As always, Nature carries sole responsibility for all editorial content.
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Chronic sleep loss has been linked to earlier mortality, metabolic syndrome, diabetes, cardiovascular disease, impaired memory and learning, and other illnesses. Untreated sleep disordered breathing (sleep apnea) has been linked to increased risk for hypertension, coronary artery disease, stroke, and heart failure.
Seventy million Americans are estimated to be affected by sleep problems, at an annual cost of approximately $15 billion in health care expenses and $50 billion in lost productivity. Sleep problems and disorders have major impacts, but have received insufficient attention in basic and clinical research, clinical practice, education, research training, and public health.
NIH funding for basic and clinical research has more than doubled since the National Center on Sleep Disorders Research (www.nhlbi.nih.gov/sleep) was created in 1993. This issue of Nature Insight highlights cutting-edge research that is advancing frontiers of new knowledge regarding functions of sleep, hypothalamic regulation, memory consolidation, sleep disorders, and dreaming. These articles summarize major advances in our knowledge of sleep and circadian neurobiology and sleep disorders, and identify opportunities for translation into improved clinical practice and public health improvement, and for the next generation of sleep-related research.
NIH is pleased to be supporting this Insight; for more information please visit www.nih.gov
