Supplements

Metalloproteins

Vol. 460, No. 7257 pp 813–862

The metalloproteins system cover

In this supplement

Metalloproteins — proteins containing metal atoms or clusters — are involved in a wide range of important biological processes. Recent advances in our understanding of metalloproteins include how enzymes containing complex metal clusters metabolize small gaseous molecules, how proteins containing iron–sulphur clusters are assembled, and how enzymes containing a single metal ion catalyse the halogenation of small organic molecules.

This Nature Insight is accompanied by a special podcast on metalloproteins, which features interviews with several of the authors.

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Editorial

Metalloproteins free access

Joshua Finkelstein

doi:10.1038/460813a


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Reviews

Structure–function relationships of anaerobic gas-processing metalloenzymes

Juan C. Fontecilla-Camps, Patricia Amara, Christine Cavazza, Yvain Nicolet & Anne Volbeda

doi:10.1038/nature08299


Metalloproteins and metal sensing

Kevin J. Waldron, Julian C. Rutherford, Dianne Ford & Nigel J. Robinson

doi:10.1038/nature08300


Function and biogenesis of iron–sulphur proteins

Roland Lill

doi:10.1038/nature08301


Molybdenum cofactors, enzymes and pathways

Günter Schwarz, Ralf R. Mendel & Markus W. Ribbe

doi:10.1038/nature08302


Mechanistic considerations of halogenating enzymes

Alison Butler & Moriah Sandy

doi:10.1038/nature08303


Design of functional metalloproteins

Yi Lu, Natasha Yeung, Nathan Sieracki & Nicholas M. Marshall

doi:10.1038/nature08304