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Inflammation

Vol. 454, No. 7203 pp 427–477

Inflammation Disease cover

Inflammation forms the basis of many physiological and pathological processes. Much is known about how inflammation is initiated, develops and resolves over the short term. But less is known about the causes and consequences of chronic inflammation, which underlies many human diseases. Recent studies have extended our understanding of chronic inflammation and the cross-talk that occurs between inflammatory responses and other physiological and pathological responses.

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Editorial

Inflammation Free access

Ursula Weiss

doi:10.1038/454427a


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Reviews

Origin and physiological roles of inflammation

Ruslan Medzhitov

doi:10.1038/nature07201


Cancer-related inflammation

Alberto Mantovani, Paola Allavena, Antonio Sica & Frances Balkwill

doi:10.1038/nature07205


The development of allergic inflammation

Stephen J. Galli, Mindy Tsai & Adrian M. Piliponsky

doi:10.1038/nature07204


From endoplasmic-reticulum stress to the inflammatory response

Kezhong Zhang & Randal J. Kaufman

doi:10.1038/nature07203


Hypothesis

The role of exercise and PGC1α in inflammation and chronic disease

Christoph Handschin & Bruce M. Spiegelman

doi:10.1038/nature07206


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Review

Integration of metabolism and inflammation by lipid-activated nuclear receptors

Steven J. Bensinger & Peter Tontonoz

doi:10.1038/nature07202