Supplements
Nature Insight: Glycochemistry & Glycobiology
Vol. 446, No. 7139 pp 999-1051
The importance of carbohydrates in biological processes has long been underappreciated. Armed with new tools for synthesizing, modifying and studying oligosaccharides and glycoconjugates, our understanding of these biomolecules is rapidly improving. This knowledge is also yielding promising candidates for carbohydrate-based diagnostics, drugs and vaccines.
In this supplement
Editorial
Glycochemistry & Glycobiology Free access
Joshua Finkelstein
doi:10.1038/446999a
Top of page
Reviews
Chemical glycosylation in the synthesis of glycoconjugate antitumour vaccines Free access
Danica P. Galoni
& David Y. Gin
doi:10.1038/nature05813
Abstract | Full Text | PDF (460KB)
Unusual sugar biosynthesis and natural product glycodiversification Free access
Christopher J. Thibodeaux, Charles E. Melançon & Hung-wen Liu
doi:10.1038/nature05814
Abstract | Full Text | PDF (704KB)
Cycling of O-linked β-N-acetylglucosamine on nucleocytoplasmic proteins Free access
Gerald W. Hart, Michael P. Housley & Chad Slawson
doi:10.1038/nature05815
Abstract | Full Text | PDF (566KB)
Glycan-based interactions involving vertebrate sialic-acid-recognizing proteins Free access
Ajit Varki
doi:10.1038/nature05816
Abstract | Full Text | PDF (781KB)
Heparan sulphate proteoglycans fine-tune mammalian physiology Free access
Joseph R. Bishop, Manuela Schuksz & Jeffrey D. Esko
doi:10.1038/nature05817
Abstract | Full Text | PDF (3,116KB)
Exploiting the defensive sugars of HIV-1 for drug and vaccine design Free access
Christopher N. Scanlan, John Offer, Nicole Zitzmann & Raymond A. Dwek
doi:10.1038/nature05818
Abstract | Full Text | PDF (1,800KB)
Synthesis and medical applications of oligosaccharides Free access
Peter H. Seeberger & Daniel B. Werz
doi:10.1038/nature05819
Abstract | Full Text | PDF (277KB)
