Supplements
RNAi Therapy
In this supplement
Related Links
Brief communication
RNA interference in adult mice -
McCaffrey, A. P. et al.
Nature 418, 38-39 (2002). doi:10.1038/418038a
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Article
Inhibition of hepatitis B virus in mice by RNA interference -
McCaffrey, A. P. et al.
Nature Biotech. 21, 639-644 (2003). doi:10.1038/nbt824
Full Text | PDF | Supplementary Information
RNAi suppresses polyglutamineinduced neurodegeneration in a model of spinocerebellar ataxia -
Xia, H. et al.
Nature Med. 10, 816-820 (2004).doi:10.1038/nm1076
Letter
Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS -
Raoul, C. et al.
Nature Med. 11, 423-428 (2005).doi:10.1038/nm1207
Full Text | PDF | Supplementary Information
Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model -
Ralph, G. S. et al.
Nature Med. 11, 429-433 (2005). doi:10.1038/nm1205
Full Text | PDF | Supplementary Information
Article
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs -
Soutschek, J. et al.
Nature 432, 173-178 (2004).doi:10.1038/nature03121
Full Text | PDF | Supplementary Information
Inhibition of respiratory viruses by nasally administered siRNA -
Bitko, V. et al.
Nature Med. 11, 50-55 (2005). doi:10.1038/nm1164
Letters
Lack of interferon response in animals to naked siRNAs -
Heidel, J. D. et al.
Nature Biotech. 22, 1579-1582 (2004). doi:10.1038/nbt1038
Full Text | PDF | Supplementary Information
Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA -
Judge, D. A. et al.
Nature Biotech. 23, 457-462 (2005). doi:10.1038/nbt1081
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Sequence-specific potent induction of IFN-a by short interfering RNA in plasmacytoid dendritic cells through TLR7 -
Hornung, V. et al.
Nature Med. 11, 263-270 (2005). doi:10.1038/nm1191
Full Text | PDF | Supplementary Information
Archive
News Feature
A crucial test -
Ericka Check
Nature Med. 11, 243-244 (2005). doi:10.1038/nm0305-243
News
New technologies deliver in treating neurological diseases -
E Singer
Nature Med. 10, 1267 (2004). doi:10.1038/nm1204-1267a
Hopes rise for RNA therapy as mouse study hits target. -
E Check
Nature 432, 136 (2004). doi:10.1038/432136b
Firm sets sights on gene silencing to protect vision -
E Check
Nature 430, 819 (2002). doi:10.1038/430819b
Gene regulation: RNA to the rescue? -
E Check
Nature 425, 10-12 (2003). doi:10.1038/425010a
News & Views
Medicine: a cholesterol connection in RNAi -
J J Rossi
Nature 432, 155-156 (2004). doi:10.1038/432155a
RNAi quashes polyQ -
N J Caplen
Nat Med. 8, 775-776 (2004). doi:10.1038/nm0804-775
siRNAs knock down hepatitis -
P D Zamore and N. Aronin
Nat Med. 9, 266-267 (2003). doi:10.1038/nm0303-266
Technology feature
RNA interference: the silent treatment -
J. Clayton
Nature 431, 599-605 (2004). doi:10.1038/431599a
Feature
Unlocking the money-making potential of RNAi -
K Howard
Nat Biotechnol. 12, 1441-1446 (2003). doi:10.1038/nbt1203-1441
Correspondence
Why RNAi makes sense -
S R Hough et al
Nat Biotechnol. 7, 731-732 (2003). doi:10.1038/nbt0703-731b
