Nanotechnology in Cancer


Nanotechnology in cancer cover

In this supplement

As cancer treatment shifts from non-specific cytotoxic molecules towards multifunctional targeted therapies, nanotechnology promises new approaches for earlier detection, diagnosis and prevention. With the impressive and rapid progress made in this area, it is hoped that nanotechnology-based applications will safely translate into the clinic to fight cancer. In this collection, a selection of papers present the opportunities, challenges and progress made in imaging, delivery systems, detection and safety of the new materials and approaches. We believe that you will enjoy this collection of papers originally published in Nature Publishing Group journals.


Current Research

in vivo biodistribution and highly efficient tumour targeting of carbon nanotubes in mice

Zhuang Liu et al.

Nature Nanotechnology 2, 47–52 (2006). doi:10.1038/nnano.2006.170

Rapid and label-free nanomechanical detection of biomarker transcripts in human RNA

J. Zhang et al.

Nature Nanotechnology 1, 214–220 (2006). doi:10.1038/nnano.2006.134

Co-delivery of drugs and DNA from cationic core–shell nanoparticles self-assembled from a biodegradable copolymer

Yong Wang, Shujun Gao, Wen-Hui Ye, Ho Sup Yoon & Yi-Yan Yang

Nature Materials 5, 791–796 (2006). doi:10.1038/nmat1737

Self-illuminating quantum dot conjugates for in vivo imaging

Min-Kyung So, Chenjie Xu, Andreas M Loening, Sanjiv S Gambhir & Jianghong Rao

Nature Biotechnology 24, 339–343 (2006). doi:10.1038/nbt1188

Temporal targeting of tumour cells and neovasculature with a nanoscale delivery system

Shiladitya Sengupta et al.

Nature 436, 568–572 (2005). doi:10.1038/nature03794

Quantum dots spectrally distinguish multiple species within the tumor milieu in vivo

Mark Stroh et al.

Nature Medicine 11, 678–682 (2005). doi:10.1038/nm1247

Cancer nanotechnology: opportunities and challenges

Mauro Ferrari

Nature Reviews Cancer 5, 161–171 (2005). doi:10.1038/nrc1566