Supplements

Malaria

In this supplement

The world is on the verge of making major inroads against malaria — a deadly disease that still claims the lives of more than 1 million people annually, mostly children less than 5 years of age. Over the past decade, scientists, large pharmaceutical companies and small biotechnology firms, governments and philanthropic organizations have come together to mount a full frontal attack on malaria, and there is now even talk of the 'E word' — that is, eradication. This collection highlights advances in the deployment of existing tools, and in the basic science of malaria — particularly those flowing from sequencing of the malaria parasite genomes — that will underpin the next generation of malaria-control tools, which will be needed if the scourge of malaria is to be eradicated.


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Editorial

Editorial

On the verge

Declan Butler and Claudia Lupp


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News and Opinion

News Feature

Malaria: The end of the beginning

After decades of work, a pioneering malaria vaccine may soon reach the final phase of clinical trials. In the first of two features on efforts against malaria, Brendan Maher reports on a vaccine that is far from perfect — but which may provide new direction and save thousands of lives.

Brendan Maher

Naturenews 451, 1042—1046 (2008)

doi:10.1038/4511042a


News

Malaria vaccine gets shot in the arm from tests

Promising results pave the way for a vaccine candidate to undergo full-blown trials across Africa.

Brendan Maher

Naturenews 456, 680—681 (2008)

doi:10.1038/456680a


News Feature

Malaria: The big push

Zambia, with help from partners around the world, is stepping up its battle against malaria. Michael Hopkin reports from the rural front line.

Michael Hopkin

Naturenews 451, 1047—1049 (2008)

doi:10.1038/4511047a


Commentary

The billion-dollar malaria moment

For years the global malaria effort has been asking for more resources. Now the field needs to figure out a systematic strategy for spending the money effectively, says Mark Grabowsky.

Mark Grabowsky

Nature 451, 1051—1052 (28 February 2008)

doi:10.1038/4511051a


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Research

Review

Malaria research in the post-genomic era

Elizabeth A. Winzele

Nature 455, 751—756 (9 October 2008) doi:10.1038/nature07361


Article

Comparative genomics of the neglected human malaria parasite Plasmodium vivax

Jane M. Carlton et al.

Nature 455, 757—763 (9 October 2008) doi:10.1038/nature07327


Article

Genome sequence of the human malaria parasite Plasmodium falciparum

Malcolm J. Gardner et al.

Nature 419, 498—511 (3 October 2002) doi:10.1038/nature01097


Article

Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii

Jane M. Carlton et al.

Nature 419, 512—519 (3 October 2002) doi:10.1038/nature01099


Letter

The genome of the simian and human malaria parasite Plasmodium knowlesi

A. Pain et al.

Nature 455, 799—803 (9 October 2008) doi:10.1038/nature07306


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Sponsor:

Special Programme for Research and Training in Tropical Diseases (TDR) Medicines for Malaria Venture (MMV) GlaxoSmithKline

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