Latest Research

  • Author Correction |

    • Belén Fadrique
    • , Selene Báez
    • , Álvaro Duque
    • , Agustina Malizia
    • , Cecilia Blundo
    • , Julieta Carilla
    • , Oriana Osinaga-Acosta
    • , Lucio Malizia
    • , Miles Silman
    • , William Farfán-Ríos
    • , Yadvinder Malhi
    • , Kenneth R. Young
    • , Cuesta C. Francisco
    • , Jurgen Homeier
    • , Manuel Peralvo
    • , Esteban Pinto
    • , Oswaldo Jadan
    • , Nikolay Aguirre
    • , Zhofre Aguirre
    •  & Kenneth J. Feeley
  • Letter |

    Imaging steady-state negative capacitance in SrTiO3/PbTiO3 superlattices with atomic resolution provides solid microscale support for this phenomenon.

    • Ajay K. Yadav
    • , Kayla X. Nguyen
    • , Zijian Hong
    • , Pablo García-Fernández
    • , Pablo Aguado-Puente
    • , Christopher T. Nelson
    • , Sujit Das
    • , Bhagawati Prasad
    • , Daewoong Kwon
    • , Suraj Cheema
    • , Asif I. Khan
    • , Chenming Hu
    • , Jorge Íñiguez
    • , Javier Junquera
    • , Long-Qing Chen
    • , David A. Muller
    • , Ramamoorthy Ramesh
    •  & Sayeef Salahuddin
  • Letter |

    A ferroelectric thin film that behaves as a single domain is found to exhibit both negative capacitance and the predicted double-well polarization–energy relationship.

    • Michael Hoffmann
    • , Franz P. G. Fengler
    • , Melanie Herzig
    • , Terence Mittmann
    • , Benjamin Max
    • , Uwe Schroeder
    • , Raluca Negrea
    • , Pintilie Lucian
    • , Stefan Slesazeck
    •  & Thomas Mikolajick
  • Letter |

    A three-dimensional photonic topological insulator is presented, made of split-ring resonators with strong magneto-electric coupling, which has an extremely wide topological bandgap, forbidding light propagation.

    • Yihao Yang
    • , Zhen Gao
    • , Haoran Xue
    • , Li Zhang
    • , Mengjia He
    • , Zhaoju Yang
    • , Ranjan Singh
    • , Yidong Chong
    • , Baile Zhang
    •  & Hongsheng Chen
  • Letter |

    • M. Amiri
    • , K. Bandura
    • , M. Bhardwaj
    • , P. Boubel
    • , M. M. Boyce
    • , P. J. Boyle
    • , C. Brar
    • , M. Burhanpurkar
    • , T. Cassanelli
    • , P. Chawla
    • , J. F. Cliche
    • , D. Cubranic
    • , M. Deng
    • , N. Denman
    • , M. Dobbs
    • , M. Fandino
    • , E. Fonseca
    • , B. M. Gaensler
    • , A. J. Gilbert
    • , A. Gill
    • , U. Giri
    • , D. C. Good
    • , M. Halpern
    • , D. S. Hanna
    • , A. S. Hill
    • , G. Hinshaw
    • , C. Höfer
    • , A. Josephy
    • , V. M. Kaspi
    • , T. L. Landecker
    • , D. A. Lang
    • , H.-H. Lin
    • , K. W. Masui
    • , R. Mckinven
    • , J. Mena-Parra
    • , M. Merryfield
    • , D. Michilli
    • , N. Milutinovic
    • , C. Moatti
    • , A. Naidu
    • , L. B. Newburgh
    • , C. Ng
    • , C. Patel
    • , U.-L. Pen
    • , T. Pinsonneault-Marotte
    • , Z. Pleunis
    • , M. Rafiei-Ravandi
    • , M. Rahman
    • , S. M. Ransom
    • , A. Renard
    • , P. Scholz
    • , J. R. Shaw
    • , S. R. Siegel
    • , K. M. Smith
    • , I. H. Stairs
    • , S. P. Tendulkar
    • , I. Tretyakov
    • , K. Vanderlinde
    •  & P. Yadav
  • Letter |

    Photometry and parallax data from the Gaia satellite provide direct observational evidence of a theoretically predicted pile-up in the cooling sequence of white dwarfs, which is associated with core crystallization.

    • Pier-Emmanuel Tremblay
    • , Gilles Fontaine
    • , Nicola Pietro Gentile Fusillo
    • , Bart H. Dunlap
    • , Boris T. Gänsicke
    • , Mark A. Hollands
    • , J. J. Hermes
    • , Thomas R. Marsh
    • , Elena Cukanovaite
    •  & Tim Cunningham
  • Letter |

    Radial growth in the roots of Arabidopsis, which is mediated by gene expression activated by the mobile PEAR1 and PEAR2 transcription factors, is initiated around protophloem-sieve-element cell files of procambial tissue.

    • Shunsuke Miyashima
    • , Pawel Roszak
    • , Iris Sevilem
    • , Koichi Toyokura
    • , Bernhard Blob
    • , Jung-ok Heo
    • , Nathan Mellor
    • , Hanna Help-Rinta-Rahko
    • , Sofia Otero
    • , Wouter Smet
    • , Mark Boekschoten
    • , Guido Hooiveld
    • , Kayo Hashimoto
    • , Ondřej Smetana
    • , Riccardo Siligato
    • , Eva-Sophie Wallner
    • , Ari Pekka Mähönen
    • , Yuki Kondo
    • , Charles W. Melnyk
    • , Thomas Greb
    • , Keiji Nakajima
    • , Rosangela Sozzani
    • , Anthony Bishopp
    • , Bert De Rybel
    •  & Ykä Helariutta
  • Letter |

    Specific ablation of mitochondrial complex III subunits in Treg cells in mice results in inflammatory disease, altered Treg gene expression and defective Treg function, indicating a key functional role for mitochondrial complex III in Treg cells.

    • Samuel E. Weinberg
    • , Benjamin D. Singer
    • , Elizabeth M. Steinert
    • , Carlos A. Martinez
    • , Manan M. Mehta
    • , Inmaculada Martínez-Reyes
    • , Peng Gao
    • , Kathryn A. Helmin
    • , Hiam Abdala-Valencia
    • , Laura A. Sena
    • , Paul T. Schumacker
    • , Laurence A. Turka
    •  & Navdeep S. Chandel
  • Letter |

    In the roots of Arabidopsis thaliana, cells with xylem identity and high levels of auxin signalling function as organizer cells that direct neighbouring vascular cambial cells to act as stem cells.

    • Ondřej Smetana
    • , Riikka Mäkilä
    • , Munan Lyu
    • , Ali Amiryousefi
    • , Filomeno Sánchez Rodríguez
    • , Miin-Feng Wu
    • , Anna Solé-Gil
    • , Marina Leal Gavarrón
    • , Riccardo Siligato
    • , Shunsuke Miyashima
    • , Pawel Roszak
    • , Tiina Blomster
    • , Jason W. Reed
    • , Suvi Broholm
    •  & Ari Pekka Mähönen
  • Letter |

    A frequently recurring nova is surrounded by an enormous cavity in space, produced as the nova’s ejecta ‘sweeps up’ the interstellar medium around the star after each eruption.

    • M. J. Darnley
    • , R. Hounsell
    • , T. J. O’Brien
    • , M. Henze
    • , P. Rodríguez-Gil
    • , A. W. Shafter
    • , M. M. Shara
    • , N. M. H. Vaytet
    • , M. F. Bode
    • , R. Ciardullo
    • , B. D. Davis
    • , R. Galera-Rosillo
    • , D. J. Harman
    • , E. J. Harvey
    • , M. W. Healy
    • , J.-U. Ness
    • , V. A. R. M. Ribeiro
    •  & S. C. Williams
  • Letter |

    A new metal–organic framework has several conformational degrees of freedom that can be modified by the external chemical environment to change the structure and trigger the uptake of a guest molecule.

    • Alexandros P. Katsoulidis
    • , Dmytro Antypov
    • , George F. S. Whitehead
    • , Elliot J. Carrington
    • , Dave J. Adams
    • , Neil G. Berry
    • , George R. Darling
    • , Matthew S. Dyer
    •  & Matthew J. Rosseinsky
  • Letter |

    X-ray observations of the evolution of a black-hole transient suggest a shrinkage of its corona, rather than a change in the inner edge of the accretion disk.

    • E. Kara
    • , J. F. Steiner
    • , A. C. Fabian
    • , E. M. Cackett
    • , P. Uttley
    • , R. A. Remillard
    • , K. C. Gendreau
    • , Z. Arzoumanian
    • , D. Altamirano
    • , S. Eikenberry
    • , T. Enoto
    • , J. Homan
    • , J. Neilsen
    •  & A. L. Stevens
  • Article |

    A hyper-stable de novo protein mimic of interleukin-2 computationally designed to not interact with a regulatory T-cell specific receptor subunit has improved therapeutic activity in mouse models of melanoma and colon cancer.

    • Daniel-Adriano Silva
    • , Shawn Yu
    • , Umut Y. Ulge
    • , Jamie B. Spangler
    • , Kevin M. Jude
    • , Carlos Labão-Almeida
    • , Lestat R. Ali
    • , Alfredo Quijano-Rubio
    • , Mikel Ruterbusch
    • , Isabel Leung
    • , Tamara Biary
    • , Stephanie J. Crowley
    • , Enrique Marcos
    • , Carl D. Walkey
    • , Brian D. Weitzner
    • , Fátima Pardo-Avila
    • , Javier Castellanos
    • , Lauren Carter
    • , Lance Stewart
    • , Stanley R. Riddell
    • , Marion Pepper
    • , Gonçalo J. L. Bernardes
    • , Michael Dougan
    • , K. Christopher Garcia
    •  & David Baker
  • Letter |

    • M. Amiri
    • , K. Bandura
    • , M. Bhardwaj
    • , P. Boubel
    • , M. M. Boyce
    • , P. J. Boyle
    • , C. Brar
    • , M. Burhanpurkar
    • , P. Chawla
    • , J. F. Cliche
    • , D. Cubranic
    • , M. Deng
    • , N. Denman
    • , M. Dobbs
    • , M. Fandino
    • , E. Fonseca
    • , B. M. Gaensler
    • , A. J. Gilbert
    • , U. Giri
    • , D. C. Good
    • , M. Halpern
    • , D. Hanna
    • , A. S. Hill
    • , G. Hinshaw
    • , C. Höfer
    • , A. Josephy
    • , V. M. Kaspi
    • , T. L. Landecker
    • , D. A. Lang
    • , K. W. Masui
    • , R. Mckinven
    • , J. Mena-Parra
    • , M. Merryfield
    • , N. Milutinovic
    • , C. Moatti
    • , A. Naidu
    • , L. B. Newburgh
    • , C. Ng
    • , C. Patel
    • , U. Pen
    • , T. Pinsonneault-Marotte
    • , Z. Pleunis
    • , M. Rafiei-Ravandi
    • , S. M. Ransom
    • , A. Renard
    • , P. Scholz
    • , J. R. Shaw
    • , S. R. Siegel
    • , K. M. Smith
    • , I. H. Stairs
    • , S. P. Tendulkar
    • , I. Tretyakov
    • , K. Vanderlinde
    •  & P. Yadav
  • Letter |

    Cryo-electron microscopy structures of feline calicivirus and its cellular receptor show that twelve copies of the minor capsid protein VP2 form a portal-like assembly arranged about a pore in the capsid shell.

    • Michaela J. Conley
    • , Marion McElwee
    • , Liyana Azmi
    • , Mads Gabrielsen
    • , Olwyn Byron
    • , Ian G. Goodfellow
    •  & David Bhella
  • Letter |

    The thermal neutron capture cross-section of 88Zr is measured to be 861,000 ± 69,000 barns, the second-largest neutron capture cross-section ever measured.

    • Jennifer A. Shusterman
    • , Nicholas D. Scielzo
    • , Keenan J. Thomas
    • , Eric B. Norman
    • , Suzanne E. Lapi
    • , C. Shaun Loveless
    • , Nickie J. Peters
    • , J. David Robertson
    • , Dawn A. Shaughnessy
    •  & Anton P. Tonchev
  • Letter |

    Wind from the most massive star in the Trapezium cluster in Orion has carved out a large and expanding cavity around the cluster, bounded by a thin, 2,600-solar-mass shell.

    • C. Pabst
    • , R. Higgins
    • , J. R. Goicoechea
    • , D. Teyssier
    • , O. Berne
    • , E. Chambers
    • , M. Wolfire
    • , S. T. Suri
    • , R. Guesten
    • , J. Stutzki
    • , U. U. Graf
    • , C. Risacher
    •  & A. G. G. M. Tielens
  • Letter |

    Allele-specific single-cell RNA sequencing provides insights into transcription kinetics, with data indicating that core promoter sequences affect burst size, whereas enhancers mainly affect burst frequency.

    • Anton J. M. Larsson
    • , Per Johnsson
    • , Michael Hagemann-Jensen
    • , Leonard Hartmanis
    • , Omid R. Faridani
    • , Björn Reinius
    • , Åsa Segerstolpe
    • , Chloe M. Rivera
    • , Bing Ren
    •  & Rickard Sandberg
  • Letter |

    In a mouse model of ischaemic stroke, regulatory T cells infiltrate the injured brain in response to the chemokines CCL1 and CCL20 and suppress excessive astrogliosis via the production of amphiregulin.

    • Minako Ito
    • , Kyoko Komai
    • , Setsuko Mise-Omata
    • , Mana Iizuka-Koga
    • , Yoshiko Noguchi
    • , Taisuke Kondo
    • , Ryota Sakai
    • , Kazuhiko Matsuo
    • , Takashi Nakayama
    • , Osamu Yoshie
    • , Hiroko Nakatsukasa
    • , Shunsuke Chikuma
    • , Takashi Shichita
    •  & Akihiko Yoshimura
  • Article |

    In physiologically normal epithelia, age-related expansion of clones that carry mutations in NOTCH1 and other driver genes is accelerated by risk factors for developing oesophageal squamous cell carcinoma, such as alcohol consumption or smoking.

    • Akira Yokoyama
    • , Nobuyuki Kakiuchi
    • , Tetsuichi Yoshizato
    • , Yasuhito Nannya
    • , Hiromichi Suzuki
    • , Yasuhide Takeuchi
    • , Yusuke Shiozawa
    • , Yusuke Sato
    • , Kosuke Aoki
    • , Soo Ki Kim
    • , Yoichi Fujii
    • , Kenichi Yoshida
    • , Keisuke Kataoka
    • , Masahiro M. Nakagawa
    • , Yoshikage Inoue
    • , Tomonori Hirano
    • , Yuichi Shiraishi
    • , Kenichi Chiba
    • , Hiroko Tanaka
    • , Masashi Sanada
    • , Yoshitaka Nishikawa
    • , Yusuke Amanuma
    • , Shinya Ohashi
    • , Ikuo Aoyama
    • , Takahiro Horimatsu
    • , Shin’ichi Miyamoto
    • , Shigeru Tsunoda
    • , Yoshiharu Sakai
    • , Maiko Narahara
    • , J. B. Brown
    • , Yoshitaka Sato
    • , Genta Sawada
    • , Koshi Mimori
    • , Sachiko Minamiguchi
    • , Hironori Haga
    • , Hiroshi Seno
    • , Satoru Miyano
    • , Hideki Makishima
    • , Manabu Muto
    •  & Seishi Ogawa
  • Letter |

    Femtosecond time-resolved X-ray diffraction reveals that in the ultrafast demagnitization of ferromagnetic iron, about 80% of the angular momentum lost from the spins is transferred to the lattice on a sub-picosecond timescale.

    • C. Dornes
    • , Y. Acremann
    • , M. Savoini
    • , M. Kubli
    • , M. J. Neugebauer
    • , E. Abreu
    • , L. Huber
    • , G. Lantz
    • , C. A. F. Vaz
    • , H. Lemke
    • , E. M. Bothschafter
    • , M. Porer
    • , V. Esposito
    • , L. Rettig
    • , M. Buzzi
    • , A. Alberca
    • , Y. W. Windsor
    • , P. Beaud
    • , U. Staub
    • , Diling Zhu
    • , Sanghoon Song
    • , J. M. Glownia
    •  & S. L. Johnson
  • Letter |

    Isolates of the Vibrio cholerae O1 serotype Ogawa from Yemen are from a single sublineage of the seventh pandemic El Tor (7PET) lineage and are susceptible to several commonly used antibiotics as well as to polymyxins.

    • François-Xavier Weill
    • , Daryl Domman
    • , Elisabeth Njamkepo
    • , Abdullrahman A. Almesbahi
    • , Mona Naji
    • , Samar Saeed Nasher
    • , Ankur Rakesh
    • , Abdullah M. Assiri
    • , Naresh Chand Sharma
    • , Samuel Kariuki
    • , Mohammad Reza Pourshafie
    • , Jean Rauzier
    • , Abdinasir Abubakar
    • , Jane Y. Carter
    • , Joseph F. Wamala
    • , Caroline Seguin
    • , Christiane Bouchier
    • , Thérèse Malliavin
    • , Bita Bakhshi
    • , Hayder H. N. Abulmaali
    • , Dhirendra Kumar
    • , Samuel M. Njoroge
    • , Mamunur Rahman Malik
    • , John Kiiru
    • , Francisco J. Luquero
    • , Andrew S. Azman
    • , Thandavarayan Ramamurthy
    • , Nicholas R. Thomson
    •  & Marie-Laure Quilici
  • Letter |

    Subglacially produced methane of microbial origin is flushed to the ice margin of the Greenland ice sheet by meltwater, contributing to a previously unaccounted for methane flux to the atmosphere.

    • Guillaume Lamarche-Gagnon
    • , Jemma L. Wadham
    • , Barbara Sherwood Lollar
    • , Sandra Arndt
    • , Peer Fietzek
    • , Alexander D. Beaton
    • , Andrew J. Tedstone
    • , Jon Telling
    • , Elizabeth A. Bagshaw
    • , Jon R. Hawkings
    • , Tyler J. Kohler
    • , Jakub D. Zarsky
    • , Matthew C. Mowlem
    • , Alexandre M. Anesio
    •  & Marek Stibal
  • Article |

    Cryo-electron microscopy structures are reported in which the full-length human α1β3γ2L GABAA receptor in lipid nanodiscs is bound to the channel-blocker picrotoxin, the competitive antagonist bicuculline, the agonist GABA, and the benzodiazepines alprazolam and diazepam.

    • Simonas Masiulis
    • , Rooma Desai
    • , Tomasz Uchański
    • , Itziar Serna Martin
    • , Duncan Laverty
    • , Dimple Karia
    • , Tomas Malinauskas
    • , Jasenko Zivanov
    • , Els Pardon
    • , Abhay Kotecha
    • , Jan Steyaert
    • , Keith W. Miller
    •  & A. Radu Aricescu
  • Letter |

    Terahertz light pulses induce transitions between a topological and a trivial phase in the Weyl semimetal WTe2 through an interlayer shear strain.

    • Edbert J. Sie
    • , Clara M. Nyby
    • , C. D. Pemmaraju
    • , Su Ji Park
    • , Xiaozhe Shen
    • , Jie Yang
    • , Matthias C. Hoffmann
    • , B. K. Ofori-Okai
    • , Renkai Li
    • , Alexander H. Reid
    • , Stephen Weathersby
    • , Ehren Mannebach
    • , Nathan Finney
    • , Daniel Rhodes
    • , Daniel Chenet
    • , Abhinandan Antony
    • , Luis Balicas
    • , James Hone
    • , Thomas P. Devereaux
    • , Tony F. Heinz
    • , Xijie Wang
    •  & Aaron M. Lindenberg
  • Letter |

    A closed-loop implantable bioelectronic device that can modulate peripheral neuronal activity is used to improve bladder function in a rat model of cystitis.

    • Aaron D. Mickle
    • , Sang Min Won
    • , Kyung Nim Noh
    • , Jangyeol Yoon
    • , Kathleen W. Meacham
    • , Yeguang Xue
    • , Lisa A. McIlvried
    • , Bryan A. Copits
    • , Vijay K. Samineni
    • , Kaitlyn E. Crawford
    • , Do Hoon Kim
    • , Paulome Srivastava
    • , Bong Hoon Kim
    • , Seunghwan Min
    • , Young Shiuan
    • , Yeojeong Yun
    • , Maria A. Payne
    • , Jianpeng Zhang
    • , Hokyung Jang
    • , Yuhang Li
    • , H. Henry Lai
    • , Yonggang Huang
    • , Sung-Il Park
    • , Robert W. Gereau IV
    •  & John A. Rogers
  • Letter |

    A high-resolution cryo-electron microscopy structure is reported for the full-length human α1β3γ2L GABAA receptor, functionally reconstituted in lipid nanodiscs.

    • Duncan Laverty
    • , Rooma Desai
    • , Tomasz Uchański
    • , Simonas Masiulis
    • , Wojciech J. Stec
    • , Tomas Malinauskas
    • , Jasenko Zivanov
    • , Els Pardon
    • , Jan Steyaert
    • , Keith W. Miller
    •  & A. Radu Aricescu
  • Letter |

    A transplantable mouse model of persistent cutaneous melanoma shows that immune-mediated tumour suppression can result in a state of melanoma–immune equilibrium, and that tissue-resident memory T cells are essential drivers of this equilibrium state.

    • Simone L. Park
    • , Anthony Buzzai
    • , Jai Rautela
    • , Jyh Liang Hor
    • , Katharina Hochheiser
    • , Maike Effern
    • , Nathan McBain
    • , Teagan Wagner
    • , Jarem Edwards
    • , Robyn McConville
    • , James S. Wilmott
    • , Richard A. Scolyer
    • , Thomas Tüting
    • , Umaimainthan Palendria
    • , David Gyorki
    • , Scott N. Mueller
    • , Nicholas D. Huntington
    • , Sammy Bedoui
    • , Michael Hölzel
    • , Laura K. Mackay
    • , Jason Waithman
    •  & Thomas Gebhardt
  • Article |

    The cryo-electron microscopy structure of human γ-secretase in complex with its substrate Notch reveals pronounced structural rearrangements compared to the apo enzyme, including formation of a β-sheet involving residues from both enzyme and substrate.

    • Guanghui Yang
    • , Rui Zhou
    • , Qiang Zhou
    • , Xuefei Guo
    • , Chuangye Yan
    • , Meng Ke
    • , Jianlin Lei
    •  & Yigong Shi
  • Letter |

    Observations at millimetre wavelengths reveal a young protostar surrounded by a disk with two differently tilted regions.

    • Nami Sakai
    • , Tomoyuki Hanawa
    • , Yichen Zhang
    • , Aya E. Higuchi
    • , Satoshi Ohashi
    • , Yoko Oya
    •  & Satoshi Yamamoto
  • Article |

    The mouse develops a developmentally and functionally distinct, non-canonical beige fat cell type as an adaptation to cold ambient temperature.

    • Yong Chen
    • , Kenji Ikeda
    • , Takeshi Yoneshiro
    • , Annarita Scaramozza
    • , Kazuki Tajima
    • , Qiang Wang
    • , Kyeongkyu Kim
    • , Kosaku Shinoda
    • , Carlos Henrique Sponton
    • , Zachary Brown
    • , Andrew Brack
    •  & Shingo Kajimura
  • Brief Communications Arising |

    • Judd D. Bowman
    • , Alan E. E. Rogers
    • , Raul A. Monsalve
    • , Thomas J. Mozdzen
    •  & Nivedita Mahesh
  • Letter |

    Analyses of over 700,000 satellite images to map the global extent of tidal flats over the past thirty years, and enable assessments of the status and likely future trajectories of these coastal ecosystems.

    • Nicholas J. Murray
    • , Stuart R. Phinn
    • , Michael DeWitt
    • , Renata Ferrari
    • , Renee Johnston
    • , Mitchell B. Lyons
    • , Nicholas Clinton
    • , David Thau
    •  & Richard A. Fuller
  • Letter |

    Neoantigen-targeting vaccines are a feasible therapy for tumours with a low mutation burden and immunologically ‘cold’ tumour microenvironment, as neoantigen-specific T cells from the peripheral blood migrate into intracranial glioblastoma, thereby altering the immune milieu of the glioblastoma.

    • Derin B. Keskin
    • , Annabelle J. Anandappa
    • , Jing Sun
    • , Itay Tirosh
    • , Nathan D. Mathewson
    • , Shuqiang Li
    • , Giacomo Oliveira
    • , Anita Giobbie-Hurder
    • , Kristen Felt
    • , Evisa Gjini
    • , Sachet A. Shukla
    • , Zhuting Hu
    • , Letitia Li
    • , Phuong M. Le
    • , Rosa L. Allesøe
    • , Alyssa R. Richman
    • , Monika S. Kowalczyk
    • , Sara Abdelrahman
    • , Jack E. Geduldig
    • , Sarah Charbonneau
    • , Kristine Pelton
    • , J. Bryan Iorgulescu
    • , Liudmila Elagina
    • , Wandi Zhang
    • , Oriol Olive
    • , Christine McCluskey
    • , Lars R. Olsen
    • , Jonathan Stevens
    • , William J. Lane
    • , Andres M. Salazar
    • , Heather Daley
    • , Patrick Y. Wen
    • , E. Antonio Chiocca
    • , Maegan Harden
    • , Niall J. Lennon
    • , Stacey Gabriel
    • , Gad Getz
    • , Eric S. Lander
    • , Aviv Regev
    • , Jerome Ritz
    • , Donna Neuberg
    • , Scott J. Rodig
    • , Keith L. Ligon
    • , Mario L. Suvà
    • , Kai W. Wucherpfennig
    • , Nir Hacohen
    • , Edward F. Fritsch
    • , Kenneth J. Livak
    • , Patrick A. Ott
    • , Catherine J. Wu
    •  & David A. Reardon
  • Letter |

    Computational design incorporating modular buried hydrogen networks produces highly orthogonal protein heterodimers.

    • Zibo Chen
    • , Scott E. Boyken
    • , Mengxuan Jia
    • , Florian Busch
    • , David Flores-Solis
    • , Matthew J. Bick
    • , Peilong Lu
    • , Zachary L. VanAernum
    • , Aniruddha Sahasrabuddhe
    • , Robert A. Langan
    • , Sherry Bermeo
    • , T. J. Brunette
    • , Vikram Khipple Mulligan
    • , Lauren P. Carter
    • , Frank DiMaio
    • , Nikolaos G. Sgourakis
    • , Vicki H. Wysocki
    •  & David Baker
  • Brief Communications Arising |

    • A. Kurnosov
    • , H. Marquardt
    • , D. J. Frost
    • , T. Boffa Ballaran
    •  & L. Ziberna