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Nature 483, 531 - 533 (7391)
Published online: 2012-03-29; | doi:10.1038/483531a

Article: Drug development: Raise standards for preclinical cancer research

  1. #40854
    2012-04-02 03:39:00 PM
    Greg M said:

    The claims presented here are pretty outlandish. Particularly relevant to "Hematology and Oncology" we now know that mice housed under different conditions with different microflora can have vastly different outcomes in any model, not just cancer. To suggest academic incompetence or outright unethical behavior is offensive, and is a particularly narrow view of why experiments are difficult to reproduce. Further, as indicated in Table 1, the entire definition of not-reproducible hinges on a priori profit motive of "robust" differences (whatever that means). There is always room for improvement in science, but this entire article is disingenuous and belittling to those of us who are on the front lines.

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