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More than one billion people — one-sixth of the world's population — suffer from neglected tropical diseases. With the drug 'pipeline' for these diseases almost dry, there is an urgent need to develop and deliver new and effective therapies.

This Outlook looks at the continuing challenges that hinder scientific innovation from reaching the clinic, despite the scientific community's concerted research activities.

Nature is pleased to acknowledge that Nature Outlook Neglected Diseases was produced with support from

Principal Sponsors

Bill & Melinda Gates Foundation  Foundation for the National Institutes of Health  the Wellcome Trust

Academic Sponsors

Burroughs Wellcome Fund  McLaughlin-Rotman Centre for Global Health (MRC)  Special Programme for Research and Training in Tropical Diseases (TDR)

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