to Nature home page
home
search






Nature3 October 2002

 Malaria

The malaria genome — and beyond



Plasmodium genomics special issue, 3rd October 2002

plasmodium article
Genome sequence of the human malaria parasite Plasmodium falciparum
MALCOLM J. GARDNER et al.
Nature 419, 498–511 (2002); doi:10.1038/nature01097
| Summary | Full Text (HTML / PDF) |

plasmodium article
Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoelii
JANE M. CARLTON et al.
Nature 419, 512–519 (2002); doi:10.1038/nature01099
| Summary | Full Text (HTML / PDF) |

plasmodium article
A proteomic view of the Plasmodium falciparum life cycle
LAURENCE FLORENS et al.
Nature 419, 520–526 (2002); doi:10.1038/nature01107
| Summary | Full Text (HTML / PDF) |

plasmodium letters
Sequence of Plasmodium falciparum chromosomes 1, 3-9 and 13
N. HALL et al.
Nature 419, 527–531 (2002); doi:10.1038/nature01095
| First Paragraph | Full Text (HTML / PDF) |

plasmodium letters
Sequence of Plasmodium falciparum chromosomes 2, 10, 11 and 14

MALCOLM J. GARDNER et al.
Nature 419, 531–534 (2002); doi:10.1038/nature01094
| First Paragraph | Full Text (HTML / PDF) |

plasmodium letters
Sequence of Plasmodium falciparum chromosome 12
RICHARD W. HYMAN et al.
Nature 419, 534–537 (2002); doi:10.1038/nature01102
| First Paragraph | Full Text (HTML / PDF) |

plasmodium letters
Analysis of the Plasmodium falciparum proteome by high-accuracy mass spectrometry
EDWIN LASONDER et al.
Nature 419, 537–542 (2002); doi:10.1038/nature01111
| First Paragraph | Full Text (HTML / PDF) |

opinion
Time to eradicate malaria
The fight against the disease needs not only money but also coherence.
Nature 419, 417 (2002); doi:10.1038/419417b
| Full Text (HTML / PDF) |

news
Weak leadership threatens anti-malaria drive
DECLAN BUTLER
Nature 419, 422 (2002); doi:10.1038/419422a
| Full Text (HTML / PDF) |

news feature
What difference does a genome make
DECLAN BUTLER
The malaria parasite's genome should provide a wealth of new scientific opportunities. But this may heighten tensions over how best to spend the scant resources allocated to malaria research and control.
Nature 419, 426–428 (2002); doi:10.1038/419426a
| Full Text (HTML / PDF) |

news feature
Mosquitoes minus malaria
TOM CLARKE
If wild populations of the mosquito that transmits malaria were replaced with insects rendered harmless by genetic engineering, the disease could finally be defeated. But that remains a big 'if', as Tom Clarke finds out.
Nature 419, 429–430 (2002); doi:10.1038/419429a
| Full Text (HTML / PDF) |

correspondence
Integrated programme is key to malaria control
Genome publication must not divert attention from basic science and public-health goals.
Nature 419, 431 (2002); doi:10.1038/419431a
| Full Text (HTML / PDF) |

plasmodium commentary
The Plasmodium genome database
JESSICA C. KISSINGER et al.
Designing and mining a eukaryotic genomics resource.
Nature 419, 490–492 (2002); doi:10.1038/419490a
| Full Text (HTML / PDF) |

plasmodium news and views
The parasite genome: The grand assault
RUSSELL F. DOOLITTLE
The complete genome sequence of the parasite responsible for most of the world's human malaria has been determined. The nature of the genome meant that this was a difficult project, requiring considerable ingenuity.
Nature 419, 493–494 (2002); doi:10.1038/419493a
| Full Text (HTML / PDF) |

plasmodium news and views
The parasite genome: Biological revelations
DYANN F. WIRTH
The genome of the malaria parasite was sequenced with the aim of learning more about how the parasite works, and with the hope that this would reveal potential drug targets. Has that hope been realized?
Nature 419, 495–496 (2002); doi:10.1038/419495a
| Full Text (HTML / PDF) |

plasmodium news and views
The mosquito genome: The post-genomic era opens
ENNIO DE GREGORIO & BRUNO LEMAITRE
The mosquito Anopheles gambiae is the main agent in the transmission of human malaria. Its genome sequence will in time help to devise control strategies, but will be a more immediate boon for insect biologists.
Nature 419, 496–497 (2002); doi:10.1038/419496a
| Full Text (HTML / PDF) |

naturejobs special report
Malaria research tools up for the future
DIANE GERSHON
Will the malaria genome open the door to new drugs, vaccines and job opportunities? Di Gershon investigates
NatureJobs 419, 4 (2002); doi:10.1038/nj6906-04a
| Full Text (HTML / PDF) |



NSU Malaria Special


Selected malaria papers from Nature's archive

Insight: Malaria
A specially commissioned set of malaria-related articles featuring in depth analysis from experts in their fields.

brief communication
Malaria: Thermoregulation in a parasite's life cycle
JUN FANG & THOMAS F. MCCUTCHAN
Nature 418, 742 (2002); doi:10.1038/418742a
| First Paragraph | Full Text (HTML / PDF) |

letters to nature
Synthetic GPI as a candidate anti-toxic vaccine in a model of malaria
LOUIS SCHOFIELD et al.
Nature 418, 785–789 (2002); doi:10.1038/nature00937
| First Paragraph | Full Text (HTML / PDF) |

letters to nature
Genetic diversity and chloroquine selective sweeps in Plasmodium falciparum
JOHN C. WOOTTON et al.
Nature 418, 320–323 (2002); doi:10.1038/nature00813
| First Paragraph | Full Text (HTML / PDF) |

letters to nature
Chromosome-wide SNPs reveal an ancient origin for Plasmodium falciparum
JIANBING MU et al.
Nature 418, 323–324 (2002); doi:10.1038/nature00836
| First Paragraph | Full Text (HTML / PDF) |

letters to nature
Climate change and the resurgence of malaria in the East African highlands
SIMON I. HAY et al.
Nature 415, 905–909 (2002); doi:10.1038/415905a
| First Paragraph | Full Text (HTML / PDF) |

news
Earliest malaria DNA found in Roman baby graveyard
ALISON ABBOTT
Nature 412, 847 (30 Aug 2001) doi: 10.1038/35091226
| Full Text (HTML / PDF) |

letters to nature
Frequent ectopic recombination of virulence factor genes in telomeric chromosome clusters of P. falciparum
L�CIO H. FREITAS-JUNIOR et al.
Nature 407, 1018–1022 (2000); doi:10.1038/35039531
| First Paragraph | Full Text (HTML / PDF) |

article
The complete nucleotide sequence of chromosome 3 of Plasmodium falciparum
S. BOWMAN et al.
Nature 400, 532–538 (1999); doi:10.1038/22964
| Summary | Full Text (HTML / PDF) |

news
Malaria meeting charts rocky path ahead
DECLAN BUTLER
Nature 388, 219 (17 Jul 1997); doi:10.1038/40731
| Full Text (HTML / PDF) |


  
  � 2002 Nature Publishing Group