15
May 2003
Aetiology: SARS virus confirmed
Experimental infections of cynomolgus macaques with the newly discovered SARS-associated coronavirus (SCV) confirm beyond reasonable doubt that it is indeed the aetiological agent of SARS (severe acute respiratory syndrome). This does not exclude the possibility that other respiratory pathogens, including human metapneumovirus and Chlamydia pneumoniae, may have exacerbated the disease in some cases. But the agents are not found consistently in SARS patients, and do not usually cause the lesions associated with SARS.
Aetiology: Koch's postulates fulfilled for SARS virus
RON A. M. FOUCHIER, THIJS KUIKEN, MARTIN SCHUTTEN, GEERT VAN
AMERONGEN, GERARD J. J. VAN DOORNUM, BERNADETTE G. VAN DEN HOOGEN, MALIK PEIRIS,
WILINA LIM, KLAUS STÖHR & ALBERT D. M. E. OSTERHAUS
Nature 423,
240 (2003); doi:10.1038/423240a
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