Table of Contents

Volume 548 Number 7666 pp135-254

10 August 2017

About the cover

The number of pollinators is in decline around the world. Multiple factors have been identified as contributing to this fall, including agricultural intensification and invasive alien species. Artificial light at night has also been suggested as a problem for nocturnal pollinators such as the elephant hawk-moth (Deilephila elpenor) shown on the cover. In this issue, Eva Knop and her colleagues test this idea in a field experiment in Switzerland. They exposed ruderal meadows to artificial light at night, and monitored nocturnal and diurnal plant-pollinator interactions and the resulting pollination service. Pollinator visits to plants fell by 62% in the illuminated plots, and fruit set of a focal plant fell by 13%. They also found that the structure of combined diurnal and nocturnal networks meant that the negative consequences of disrupted nocturnal pollination could negatively affect daytime pollinator communities as well. The findings suggest that artificial light at night, which is spreading at an estimated rate of 6% per year, poses yet another threat to pollinators and the service they provide. Cover image: Malcolm Schuyl/Alamy

This Week

Editorials

Top

World View

Top

Research Highlights

Top

Seven Days

Top

News in Focus

Feature

Top

comment

  • Shake up conferences

    Emojis, smartphone technologies and revamped guidelines would boost transparency at scientific meetings, say Shai D. Silberberg and colleagues.

Books and Arts

Top
  • Evolution: Parallel lives

    Kevin Padian hails a stunning, provocative book probing evolutionary mechanisms.

    • Review of Improbable Destinies: Fate, Chance, and the Future of Evolution
      Jonathan B. Losos
  • Books in brief

    Barbara Kiser reviews five of the week's best science picks.

Correspondence

Top

Careers

Features

Top

Q&As

Top

naturejobs job listings and advertising features

Futures

  • Legale

    Seconds to disaster.

    • Vernor Vinge

research

Brief Communication Arising

Top

Articles

Top
  • The complete connectome of a learning and memory centre in an insect brain

    • Katharina Eichler
    • Feng Li
    • Ashok Litwin-Kumar
    • Youngser Park
    • Ingrid Andrade
    • Casey M. Schneider-Mizell
    • Timo Saumweber
    • Annina Huser
    • Claire Eschbach
    • Bertram Gerber
    • Richard D. Fetter
    • James W. Truman
    • Carey E. Priebe
    • L. F. Abbott
    • Andreas S. Thum
    • Marta Zlatic
    • Albert Cardona

    The complete, synapse-resolution connectome of the Drosophila larval mushroom body.

Letters

Top
  • No large population of unbound or wide-orbit Jupiter-mass planets

    • Przemek Mróz
    • Andrzej Udalski
    • Jan Skowron
    • Radosław Poleski
    • Szymon Kozłowski
    • Michał K. Szymański
    • Igor Soszyński
    • Łukasz Wyrzykowski
    • Paweł Pietrukowicz
    • Krzysztof Ulaczyk
    • Dorota Skowron
    • Michał Pawlak

    In an analysis of a large sample of microlensing events, a few suggest the existence of Earth-mass free-floating planets, but only the expected number of Jupiter-mass free-floating objects were detected.

  • High-temperature crystallization of nanocrystals into three-dimensional superlattices

    • Liheng Wu
    • Joshua J. Willis
    • Ian Salmon McKay
    • Benjamin T. Diroll
    • Jian Qin
    • Matteo Cargnello
    • Christopher J. Tassone

    A bottom-up process to achieve rapid growth of micrometre-sized three-dimensional nanocrystal superlattices during colloidal synthesis at high temperatures is revealed by in situ small-angle X-ray scattering; the process is applicable to several colloidal materials.

  • Global patterns of drought recovery

    • Christopher R. Schwalm
    • William R. L. Anderegg
    • Anna M. Michalak
    • Joshua B. Fisher
    • Franco Biondi
    • George Koch
    • Marcy Litvak
    • Kiona Ogle
    • John D. Shaw
    • Adam Wolf
    • Deborah N. Huntzinger
    • Kevin Schaefer
    • Robert Cook
    • Yaxing Wei
    • Yuanyuan Fang
    • Daniel Hayes
    • Maoyi Huang
    • Atul Jain
    • Hanqin Tian

    A global analysis of gross primary productivity reveals that drought recovery is driven by climate and carbon cycling, with recovery longest in the tropics and high northern latitudes, and with impacts increasing over the twentieth century.

    See also
  • Artificial light at night as a new threat to pollination

    • Eva Knop
    • Leana Zoller
    • Remo Ryser
    • Christopher Gerpe
    • Maurin Hörler
    • Colin Fontaine

    The pollination service provided by nocturnal flower visitors is disrupted near streetlamps, which leads to a reduced reproductive output of the plant that cannot be compensated for by daytime pollinators; in addition, the structure of combined nocturnal and diurnal pollination networks facilitates the spread of the consequences of disrupted night-time pollination to daytime pollinators.

  • Genetic origins of the Minoans and Mycenaeans

    • Iosif Lazaridis
    • Alissa Mittnik
    • Nick Patterson
    • Swapan Mallick
    • Nadin Rohland
    • Saskia Pfrengle
    • Anja Furtwängler
    • Alexander Peltzer
    • Cosimo Posth
    • Andonis Vasilakis
    • P. J. P. McGeorge
    • Eleni Konsolaki-Yannopoulou
    • George Korres
    • Holley Martlew
    • Manolis Michalodimitrakis
    • Mehmet Özsait
    • Nesrin Özsait
    • Anastasia Papathanasiou
    • Michael Richards
    • Songül Alpaslan Roodenberg
    • Yannis Tzedakis
    • Robert Arnott
    • Daniel M. Fernandes
    • Jeffery R. Hughey
    • Dimitra M. Lotakis
    • Patrick A. Navas
    • Yannis Maniatis
    • John A. Stamatoyannopoulos
    • Kristin Stewardson
    • Philipp Stockhammer
    • Ron Pinhasi
    • David Reich
    • Johannes Krause
    • George Stamatoyannopoulos

    New genome-wide data for ancient, Bronze Age individuals, including Minoans, Mycenaeans, and southwestern Anatolians, show that Minoans and Mycenaeans were genetically very similar yet distinct, supporting the idea of continuity but not isolation in the history of populations of the Aegean.

  • Prolonged Mek1/2 suppression impairs the developmental potential of embryonic stem cells

    • Jiho Choi
    • Aaron J. Huebner
    • Kendell Clement
    • Ryan M. Walsh
    • Andrej Savol
    • Kaixuan Lin
    • Hongcang Gu
    • Bruno Di Stefano
    • Justin Brumbaugh
    • Sang-Yong Kim
    • Jafar Sharif
    • Christopher M. Rose
    • Arman Mohammad
    • Junko Odajima
    • Jean Charron
    • Toshi Shioda
    • Andreas Gnirke
    • Steven Gygi
    • Haruhiko Koseki
    • Ruslan I. Sadreyev
    • Andrew Xiao
    • Alexander Meissner
    • Konrad Hochedlinger

    Long-term culture of male embryonic stem cells in naive conditions containing Mek1/2 and Gsk3a/b inhibitors leads to irreversible changes in epigenetic and genomic stability that compromise their in vivo developmental potential.

    See also
    See also
  • Metabolic control of TH17 and induced Treg cell balance by an epigenetic mechanism

    • Tao Xu
    • Kelly M. Stewart
    • Xiaohu Wang
    • Kai Liu
    • Min Xie
    • Jae Kyu Ryu
    • Ke Li
    • Tianhua Ma
    • Haixia Wang
    • Lu Ni
    • Saiyong Zhu
    • Nan Cao
    • Dongwei Zhu
    • Yu Zhang
    • Katerina Akassoglou
    • Chen Dong
    • Edward M. Driggers
    • Sheng Ding

    Metabolic changes in T cells can affect the genomic methylation status of key transcription factors and regulate the fate decision between induced regulatory T cells and T helper 17 cells.

  • Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS

    • Zhan Yao
    • Rona Yaeger
    • Vanessa S. Rodrik-Outmezguine
    • Anthony Tao
    • Neilawattie M. Torres
    • Matthew T. Chang
    • Matthias Drosten
    • Huiyong Zhao
    • Fabiola Cecchi
    • Todd Hembrough
    • Judith Michels
    • Hervé Baumert
    • Linde Miles
    • Naomi M. Campbell
    • Elisa de Stanchina
    • David B. Solit
    • Mariano Barbacid
    • Barry S. Taylor
    • Neal Rosen

    Hypoactive BRAF mutants bind more tightly than wild type to the upstream regulator RAS, thus amplifying ERK signalling; tumours expressing these mutants require coexistent mechanisms for RAS activation to grow and are sensitive to their inhibition.

  • A Braf kinase-inactive mutant induces lung adenocarcinoma

    • Patricia Nieto
    • Chiara Ambrogio
    • Laura Esteban-Burgos
    • Gonzalo Gómez-López
    • María Teresa Blasco
    • Zhan Yao
    • Richard Marais
    • Neal Rosen
    • Roberto Chiarle
    • David G. Pisano
    • Mariano Barbacid
    • David Santamaría

    Kinase-inactive Braf mutants can initiate the development of lung adenocarcinoma in mice; co-expression of activated Kras enhances tumour initiation and progression, and wild-type Braf is required to sustain tumorigenesis.

  • Proteins evolve on the edge of supramolecular self-assembly

    • Hector Garcia-Seisdedos
    • Charly Empereur-Mot
    • Nadav Elad
    • Emmanuel D. Levy

    Introducing a single ‘sticky’ (hydrophobic) amino acid by point mutation into symmetric protein complexes frequently triggers their association into higher-order assemblies, without affecting their native fold and structure.