Gene editing: CRISPR book review — Doudna responds

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Nathaniel Comfort suggests that the purpose of our book A Crack in Creation is to show that I am “the true hero of CRISPR” (Nature 546, 3031; 2017). On the contrary, the book offers my personal reflections as CRISPR–Cas gene editing took off, viewed from the perspective of my research team at the University of California, Berkeley.

My aim in writing this book with my former student Sam Sternberg was to demonstrate the importance of basic research and the value of collaboration in developing this groundbreaking technology. It describes the crucial scientific contributions and insights of our collaborators Emmanuelle Charpentier and her student Krzysztof Chylinski, for example.

The success of our approach has now been abundantly confirmed by the rapid application of CRISPR–Cas gene editing in virtually all types of cells and settings.

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  1. University of California, Berkeley, USA.

    • Jennifer Doudna

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  1. Report this comment #70341

    john crance said:

    I'm 1/3rd through this book and I don't see anything like what NC is promoting. I suspect there is a jealous element at play here!

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