Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Cancer

Tumour stem-cell surprises

Nature volume 543, pages 626–627 (2017)Cite this article

Subjects

Stem-cell divisions are thought to be essential to tumour growth. Targeted removal of a specific stem-cell population reveals its role in tumour development and in the growth of tumours formed by cell migration to distant sites. See Article p.676

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Tumour stem cells.

Notes

  1. See all news & views

References

  1. Nassar, D. & Blanpain, C. Annu. Rev. Pathol. 11, 47–76 (2016).

    Article  CAS  Google Scholar 

  2. Visvader, J. E. & Clevers, H. Nature Cell Biol. 18, 349–355 (2016).

    Article  CAS  Google Scholar 

  3. Barker, N. et al. Nature 457, 608–611 (2009).

    Article  CAS  ADS  Google Scholar 

  4. de Sousa e Melo, F. et al. Nature 543, 676–680 (2017).

    Article  CAS  ADS  Google Scholar 

  5. Buczacki, S. J. A. et al. Nature 495, 65–69 (2013).

    Article  CAS  ADS  Google Scholar 

  6. Tetteh, P. W. et al. Cell Stem Cell 18, 203–213 (2016).

    Article  CAS  Google Scholar 

  7. Tian, H. et al. Nature 478, 255–259 (2011).

    Article  CAS  ADS  Google Scholar 

  8. Tetteh, P. W., Farin, H. F. & Clevers, H. Trends Cell Biol. 25, 100–108 (2015).

    Article  CAS  Google Scholar 

  9. Schwitalla, S. et al. Cell 152, 25–38 (2013).

    Article  CAS  Google Scholar 

  10. Davis, H. et al. Nature Med. 21, 62–70 (2015).

    Article  CAS  ADS  Google Scholar 

  11. Schepers, A. G. et al. Science 337, 730–735 (2012).

    Article  CAS  ADS  Google Scholar 

  12. Shimokawa, M. et al. Nature http://dx.doi.org/10.1038/nature22081 (2017).

  13. Junttila, M. R. et al. Sci. Transl. Med. 7, 314ra186 (2015).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Florian R. Greten is at the Institute for Tumour Biology and Experimental Therapy, Georg-Speyer-Haus, 60596 Frankfurt, Germany.,

    Florian R. Greten

Authors
  1. Florian R. Greten
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Florian R. Greten.

Related links

Related links

Related links in Nature Research

Cancer: A targeted treatment with off-target risks

Cancer: Double trouble for tumours

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Greten, F. Tumour stem-cell surprises. Nature 543, 626–627 (2017). https://doi.org/10.1038/543626a

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/543626a

This article is cited by

Search

Advanced search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer