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Chemical biology

Protein modification in a trice

Organometallic reagents have been developed that chemically modify proteins and peptides specifically at cysteine amino-acid residues — potentially offering a general route to making therapeutically useful compounds. See Letter p.687

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Figure 1: Site-selective reactions with proteins.

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Correspondence to Heather Maynard.

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Maynard, H. Protein modification in a trice. Nature 526, 646–647 (2015). https://doi.org/10.1038/526646b

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