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Molecular biology

Salvaging the genome

Nature volume 524, pages 40–41 (2015)Cite this article

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Overexpression of the enzyme cytidine deaminase allows the incorporation of abnormally modified nucleotides into DNA, leading to cell death. This discovery might point the way to treating some cancers. See Letter p.114

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Figure 1: Salvage for cell death.

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Authors and Affiliations

  1. Sharanya Sivanand and Kathryn E. Wellen are in the Department of Cancer Biology, Abramson Family Cancer Research Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.,

    Sharanya Sivanand & Kathryn E. Wellen

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  1. Sharanya Sivanand
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  2. Kathryn E. Wellen
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Correspondence to Kathryn E. Wellen.

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Sivanand, S., Wellen, K. Salvaging the genome. Nature 524, 40–41 (2015). https://doi.org/10.1038/nature14638

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