Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Developmental biology

Nanotubes in the niche

In fruit flies, protrusions can extend from stem cells in the testes to cells in a regulatory hub, mediating intercellular signalling and stem-cell maintenance. The implications of this finding are presented here from two angles. See Letter p.329

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Maintenance of germline stem cells.

Notes

  1. See all news & views

References

  1. Inaba, M., Buszczak, M. & Yamashita, Y. M. Nature 523, 329–332 (2015).

    Article  ADS  CAS  Google Scholar 

  2. Browne, N. E. J. Exp. Zool. 7, 1–23 (1909).

    Article  Google Scholar 

  3. Spemann, H. & Mangold, H. Wilhelm Roux's Arch. Dev. Biol. 109, 599–638 (1924).

    Google Scholar 

  4. Huang, H. & Kornberg, T. B. eLife 4, e06114 (2015).

    Article  Google Scholar 

  5. Roy, S., Huang, H., Liu, S. & Kornberg, T. B. Science 343, 1244624 (2014).

    Article  Google Scholar 

  6. Bischoff, M. et al. Nature Cell Biol. 15, 1269–1281 (2013).

    Article  CAS  Google Scholar 

  7. Sanders, T. A., Llagostera, E. & Barna, M. Nature 497, 628–632 (2013).

    Article  ADS  CAS  Google Scholar 

  8. Stanganello, E. et al. Nature Commun. 6, 5846 (2015).

    Article  ADS  CAS  Google Scholar 

  9. Kawase, E., Wong, M. D., Ding, B. C. & Xie, T. Development 131, 1365–1375 (2004).

    Article  CAS  Google Scholar 

  10. Zheng, Q., Wang, Y., Vargas, E. & DiNardo, S. Dev. Biol. 357, 202–210 (2011).

    Article  CAS  Google Scholar 

  11. Guo, Z. & Wang, Z. Development 136, 3627–3635 (2009).

    Article  CAS  Google Scholar 

  12. Hayashi, Y., Kobayashi, S. & Nakato, H. J. Cell Biol. 187, 473–480 (2009).

    Article  CAS  Google Scholar 

  13. Leatherman, J. L. & Dinardo, S. Nature Cell Biol. 12, 806–811 (2010).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Thomas B. Kornberg or Lilach Gilboa.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kornberg, T., Gilboa, L. Nanotubes in the niche. Nature 523, 292–293 (2015). https://doi.org/10.1038/nature14631

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature14631

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing