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Biological techniques

Edit the genome to understand it

Genome editing followed by sequencing has now been used to engineer and analyse every variation of several stretches of human DNA in living cells, providing insight into the function of each constituent nucleotide molecule. See Letter p.120

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Figure 1: The search for meaning.

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Correspondence to Fyodor D. Urnov.

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Urnov, F. Edit the genome to understand it. Nature 513, 40–41 (2014). https://doi.org/10.1038/nature13659

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