Many enzymes form 'assembly lines' containing a series of catalytic modules. Visualization of how the structure of a module shifts during catalysis provides a clearer idea of how such enzymes work. See Article p.512 & Letter p.560
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Leadlay, P. Enzyme assembly line pictured. Nature 510, 482–483 (2014). https://doi.org/10.1038/nature13505
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DOI: https://doi.org/10.1038/nature13505