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Metabolism

Targeting a fat-accumulation gene

An enzyme that links two metabolic hubs has been found to be upregulated in the fat cells of overweight mice. Inhibition of the gene encoding this enzyme protects mice from diet-induced obesity. See Letter p.258

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Figure 1: Accelerating fat-cell metabolism.

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Correspondence to Charles Brenner.

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Brenner, C. Targeting a fat-accumulation gene. Nature 508, 194–195 (2014). https://doi.org/10.1038/508194a

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