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Cancer

Persistence of leukaemic ancestors

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The early development of acute leukaemias is assumed for the most part to be clinically silent and transient. But it now seems that ancestral precancerous cells are identifiable and persistent. See Article p.328

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Figure 1: Different routes to acute myeloid leukaemia.

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Correspondence to Nicola E. Potter or Mel Greaves.

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Potter, N., Greaves, M. Persistence of leukaemic ancestors. Nature 506, 300–301 (2014). https://doi.org/10.1038/nature13056

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