Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Stem cells

Reprogramming in situ

Cellular reprogramming to a stem-cell state has now been achieved in tissues of genetically engineered mice. This work signals a future for regenerative medicine in which tissue fates might be manipulated in living organisms. See Article p.340

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Rent or buy this article

Prices vary by article type

from$1.95

to$39.95

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Pluripotent stem cells and their potential.

Notes

  1. *This article and the paper under discussion1 were published online on 11 September 2013.

References

  1. Abad, M. et al. Nature 502, 340–345 (2013).

    Article  ADS  CAS  Google Scholar 

  2. Macfarlan, T. S. et al. Nature 487, 57–63 (2012).

    Article  ADS  CAS  Google Scholar 

  3. Tesar, P. J. et al. Nature 448, 196–199 (2007).

    Article  ADS  CAS  Google Scholar 

  4. Ng, R. K. et al. Nature Cell Biol. 10, 1280–1290 (2008).

    Article  CAS  Google Scholar 

  5. Leitch, H. G. et al. Nature Struct. Mol. Biol. 20, 311–316 (2013).

    Article  CAS  Google Scholar 

  6. Ficz, G. et al. Cell Stem Cell 13, 351–359 (2013).

    Article  CAS  Google Scholar 

  7. Xu, R. H. et al. Nature Biotechnol. 20, 1261–1264 (2002).

    Article  CAS  Google Scholar 

  8. Bernardo, A. S. et al. Cell Stem Cell 9, 144–155 (2011).

    Article  CAS  Google Scholar 

  9. Warren, L. et al. Cell Stem Cell 7, 618–630 (2010).

    Article  CAS  Google Scholar 

  10. Hou, P. et al. Science 341, 651–654 (2013).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to George Q. Daley.

Rights and permissions

Reprints and permissions

About this article

Cite this article

De Los Angeles, A., Daley, G. Reprogramming in situ. Nature 502, 309–310 (2013). https://doi.org/10.1038/nature12559

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nature12559

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing