The enzyme co-substrate SAM has long been known to have two chemically distinct roles. A study of the CmoA enzyme suggests that SAM has a third trick up its sleeve — it forms species known as ylides. See Letter p.123
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Notes
*This article and the paper under discussion3 were published online on 15 May 2013.
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Landgraf, B., Booker, S. The ylide has landed. Nature 498, 45–47 (2013). https://doi.org/10.1038/nature12247
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DOI: https://doi.org/10.1038/nature12247