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Stem Cells

A unifying theory for the crypt

A long-standing ambiguity has been whether quiescent cells located in intestinal crypt structures are stem cells. The answer seems to be yes and no, depending on how one defines the term stem cell. See Article p.65

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Figure 1: Complexities of intestinal stem cells.

Notes

  1. *This article and the paper under discussion1 were published online on 27 February 2013.

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Correspondence to Hans Clevers.

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Clevers, H. A unifying theory for the crypt. Nature 495, 53–54 (2013). https://doi.org/10.1038/nature11958

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