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Asymmetric synthesis

Relay catalysis at a boron centre

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A boron complex catalyses the addition of allyl groups — hydrocarbon motifs — to 'activated imines' in a relay-like process, generating synthetically useful compounds as single mirror-image isomers. See Letter p.216

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Figure 1: An asymmetric allyl-transfer reaction.
Figure 2: Catalytic cycle.

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Correspondence to Glenn C. Micalizio.

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Jeso, V., Micalizio, G. Relay catalysis at a boron centre. Nature 494, 179–181 (2013). https://doi.org/10.1038/494179a

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